A5100433718- Hepatocellular Carcinoma Treatment and Prognosis
- Cancer, Lipids, and Metabolism
- Liver Disease Diagnosis and Treatment
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Pancreatic and Hepatic Oncology Research
- Liver Disease and Transplantation
- Radiomics and Machine Learning in Medical Imaging
- Renal cell carcinoma treatment
- Cytokine Signaling Pathways and Interactions
- Healthcare Systems and Public Health
- Lung Cancer Research Studies
- Gastrointestinal Bleeding Diagnosis and Treatment
- Ferroptosis and cancer prognosis
- Gastric Cancer Management and Outcomes
- Medical Research and Treatments
- MRI in cancer diagnosis
- Ovarian cancer diagnosis and treatment
- Cancer Immunotherapy and Biomarkers
- Colorectal Cancer Treatments and Studies
- Gastrointestinal Tumor Research and Treatment
- NF-κB Signaling Pathways
- interferon and immune responses
- Proteoglycans and glycosaminoglycans research
- Cancer, Hypoxia, and Metabolism
- Gastrointestinal disorders and treatments
University of Electronic Science and Technology of China
2022-2024
Shaanxi Provincial People's Hospital
2023
Fourth People's Hospital of Sichuan Province
2020-2023
University of Science and Technology of China
2023
Qingdao University
2023
Affiliated Hospital of Qingdao University
2023
Southeast University
2021-2022
Second Affiliated Hospital of Nanjing Medical University
2022
Sun Yat-sen University
2018-2021
Sun Yat-sen University Cancer Center
2018-2021
To construct a predictive model of short-term response and overall survival for transcatheter arterial chemoembolization (TACE) treatment in hepatocellular carcinoma (HCC) patients based on non-contrast computed tomography (NC-CT) radiomics clinical features.Ninety-four HCC who underwent CT scanning 1 week before the first TACE were retrospectively recruited divided randomly into training group (n = 47) validation 47). NC-CT data extracted using MaZda software, compound was calculated from...
Hepatocellular carcinoma (HCC) recurrence is a clinical challenge. An accurate prediction system for patients with HCC needed, since the choice of treatment strategies very important.A total 804 who underwent curative resection at Sun Yat-sen University Cancer Center were included in this study. Demographics, clinicopathological data, and follow-up information collected.A logistic regression analysis was conducted to investigate relationships between features recurrence. Tumor size...
To evaluate and compare the predictive performance of different deep learning models using gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid (Gd-EOB-DTPA)-enhanced MRI in predicting microvascular invasion (MVI) hepatocellular carcinoma.The data 233 patients with pathologically confirmed carcinoma (HCC) treated at our hospital from June 2016 to 2021 were retrospectively analyzed. Three constructed based on three delineate methods region interest (ROI) Darwin Scientific Research...
As one of the most common malignant tumors in clinical practice, hepatocellular carcinoma (HCC) is a major threat to human health, where alpha-fetoprotein (AFP) widely used for early screening and diagnoses. However, level AFP would not elevate about 30-40% HCC patients, which clinically referred as AFP-negative HCC, with small at an stage atypical imaging features, making it difficult distinguish benign from by alone.A total 798 majority being HBV-positive, were enrolled study randomized...
Abstract There is a lack of effective programmed cell death protein 1 (PD-1)‐targeted immunotherapy with good tolerability in patients advanced hepatocellular carcinoma (HCC) and severely compromised liver function. We assessed patient outcomes after combined camrelizumab molecular targeted therapy multicenter cohort study China. The included 99 HCC (58 Child-Pugh A 41 B), 84 them received from January 10, 2019, to March 31, 2021. Overall survival (OS), progression-free (PFS), objective...
Optimal treatment of hepatocellular carcinoma (HCC) involving portal vein tumor thrombus (PVTT) remains controversial. A total 627 HCC patients with PVTT after initial one the following at Affiliated Tumor Hospital Guangxi Medical University: liver resection (LR, n = 225), transarterial chemoembolization (TACE, 298) or sorafenib (n 104) were recruited and randomly divided into training cohort 314) internal validation 313). Survival analysis repeated stratifying by Cheng type. Resection led...
Hepatocellular carcinoma (HCC) is a kind of tumor with high invasiveness, and patients advanced HCC have higher risk early death. The aim the present study was to identify factors death in establish predictive nomograms.Death that occurred within 3 months initial diagnosis defined as Patients diagnosed stage IV between 2010 2015 were collected from Surveillance, Epidemiology, End Results database for model establishment verification. Univariable multivariable logistic regression analyses...
Early identification of patients at risk for surgical complications enables surgeons to make better treatment decisions and optimize resource utilization. We propose develop a nomogram predicting the moderate-to-severe liver surgery-specific after hepatectomy in hepatocellular carcinoma (HCC) patients.
To establish a prediction model of acute upper gastrointestinal rebleeding (AUGIRB) for elderly patients by combining and applying multiple indicators.A retrospective observational study was conducted. The clinical data 161 (age ≥ 65 years old) who suffered from bleeding (AUGIB) were hospitalized in Shanghai General Hospital July 2018 to December 2020 recorded. divided into the group (31 cases) non-rebleeding (130 according whether occurred. Univariate analysis adopted screen AUGIRB-related...
Inadequate volume of future liver remnant (FLR) is a major challenge for hepatobiliary surgeons treating large or multiple tumors. As an alternative to associating partition and portal vein ligation (ALPPS) staged hepatectomy venous deprivation (LVD) using stage 1 interventional radiology vascular embolization combined with 2 open resection have been used.A novel modified LVD technique was performed in patient pancreatic neuroendocrine tumor metastases by laparoscopic the right hepatic vein,...
Objective To evaluate the prognostic significance of preoperative serum gamma glutamyl transpeptidase (GGT) level in patients with hepatocellular carcinoma (HCC) after liver resection. Methods A total 432 undergoing hepatectomy for HCC were divided into normal GGT group (175 GGT≤50 U/L) and high (257 GGT>50 U/L). After balancing baseline characteristics by propensity score analysis, disease-free survival (DFS) overall (OS) compared between two groups. Independent risk factors...
Abstract Background Hepatocellular carcinoma (HCC) is a kind of tumor with insidious early symptoms and high invasiveness, it often in the advanced stage when clinically discovered. Patients HCC have higher risk death (survival time ≤ 3 months). This study aims to identify factors patients establish predictive nomograms. Methods diagnosed IV between 2010 2015 were collected from Surveillance, Epidemiology, End Results (SEER) database for model establishment verification. The univariate...
Abstract Background/purpose : Lenvatinib was found to be non-inferior sorafenib in a Phase 3 REFLECT trial on advanced hepatocellular carcinoma. However, patients with liver tumor volume of greater than 50% total or main portal vein thrombus, which often occurs clinical practice, were excluded from the trial. This study aimed examine safety and efficacy lenvatinib beyond indications real-world setting. Method retrospective, single-center observational focused unresectable carcinoma (u-HCC)...
Abstract Background To analyze associations between the strength of expression 5-hydroxymethylcytosine (5hmC) and survival outcomes Chinese hepatoblastoma patients. Methods We collected analyzed clinical data patients aged <15 years treated at Sun Yat-Sen University Cancer Center or First Affiliated Hospital Yat-sen from Feb 2010 to Sept 2018. Patients were according Children's Oncology Group protocol. Specimens for pathology by biopsy surgical resection before initiation chemotherapy....