A5102823881- Folate and B Vitamins Research
- Nutritional Studies and Diet
- Pregnancy and preeclampsia studies
- Blood Pressure and Hypertension Studies
- Liver Disease Diagnosis and Treatment
- Cardiovascular Health and Risk Factors
- Esophageal and GI Pathology
- Gastroesophageal reflux and treatments
- Obesity, Physical Activity, Diet
- RNA modifications and cancer
- Nutrition and Health in Aging
- Birth, Development, and Health
- Prostate Cancer Treatment and Research
- Gestational Diabetes Research and Management
- Cancer, Lipids, and Metabolism
- Cancer-related molecular mechanisms research
- Sulfur Compounds in Biology
- Lipoproteins and Cardiovascular Health
- Cardiovascular Disease and Adiposity
- Cancer Risks and Factors
- Vitamin D Research Studies
Hunan Normal University
2019-2024
Hunan Provincial People's Hospital
2019-2024
Objective: Recently, ribosome binding protein 1 (RRBP1) is reported to be involved in tumorigenesis. However, the expression and clinical significance of RRBP1 prostate cancer (PCa) remains unknown. This study aimed investigate PCa. Materials methods: was firstly detected 6 cases PCa matched adjacent non-cancerous tissues by reverse transcription-quantitative PCR (RT-qPCR) Western blot. Then, further 127 40 immunohistochemistry (IHC). The relationship with clinical-pathological characters...
Objectives Hyperhomocysteinemia is an independent risk factor for cardiovascular diseases. We aimed to investigate the prevalence and factors hyperhomocysteinemia, especially modifiable lifestyle factors, such as smoking behaviour dietary factors. Design Population-based cross-sectional study. Setting Hunan Province, China Participants A total of 4012 participants completed study, between July 2013 March 2014. The median age 55 (interquartile range: 45–63) years, with 1644 males (41%) 2368...
Associated with reduced hydrogen sulfide (H2 S) production in Hcy metabolic disorders, Plasma accumulation can bring about vascular dysfunction. Nevertheless, recently proposed therapies for damage by estrogen could contribute to promoting endogenous production. This study explores whether come into play protection hyperhomocysteinemia and hypertensive patients at a population level, then analyses the specific mechanism of homocysteine (Hcy)-treated human umbilical vein endothelial cells...
Objective To assess whether cumulative exposure of unhealthy lifestyles is associated with HTH in Chinese adults and to explore the combination lifestyles. Methods This study combined a community-based cross-sectional 1:1 matched case–control using propensity scores among six randomly selected districts from Hunan Province, China. We recruited 5,258 people, whom 4,012 met criteria. Lifestyles personal characteristics were collected by questionnaire. Lifestyle score was calculated cigarette...
Aims To explore the effect of plasma homocysteine (Hcy) on cardiometabolic multimorbidity (CMM) among Chinses adults. Methods This study combined a community-based cross-sectional with 1:1 matched case–control using propensity score method adults aged over 30 years in six districts randomly selected from Hunan Province, China. We recruited 5,258 people, whom 4,012 met criteria were enrolled. CMM was defined as coexistence two or more diseases, including diabetes, hypertension, coronary heart...
Previous studies have explored the relationship between body fat percentage (BFP) and hypertension or homocysteine. However, evidence on constancy of association remains inconclusive in postmenopausal women. The aim this study was to investigate BFP H-type This cross-sectional included 1,597 eligible female patients with hypertension. Homocysteine levels ≥10 mmol/L were defined as calculated by measuring patients' physical parameters. Subjects divided into 4 groups according quartiles (Q1:...
Background Increasing evidence suggests that hyperhomocysteinemia (HHcy) and hyperlipidemia have been recognized as two independent risks for cardiovascular disease. However, the association between HHcy in hypertensive patients has not systemically elucidated. The aim of this study was to investigate relation very low-density lipoprotein (VLDL) patients.Methods From July 2013 March 2014, a large cross-sectional performed using 4012 participants from urban rural communities Hunan province,...
Recent studies have reported better predictive performance of triglyceride glucose (TyG) index for cardiovascular events in women, however, whether this association persists postmenopausal women is inconclusive. We investigated the between TyG and H-type hypertension (HHT) women. 1,301 eligible with were included cross-sectional study. Concomitant homocysteine levels >10 μmol/L defined as hypertension. The was calculated ln [triglycerides (mg/dl) × fasting (mg/dl)/2]. Multivariable logistic...
Background: We aim to examine the relationship between age at menarche and hyperhomocysteinemia in women Hunan Province. Methods: Participants were required complete a questionnaire that included menarche, lifestyle habits, other baseline information, blood biochemical parameters cross-sectional study. The association was examined by Multivariable adjusted logistic regression. Results: A cohort of 2008 with mean 60.11 years (aged from 18.0 88.0 years) this After adjustment for confounding...
Objective By investigating the obesity of adult population in Hunan, we explored relationship between body mass index (BMI) [including waist circumference (WC), waist-to-hip ratio (WHR), waist-to-body (WHtR) and H-type hypertension] predicting hypertension. Methods A multi-stage random sampling method was used to conduct a questionnaire survey, physical examination laboratory testing on 4 012 adults >30 years old 6 districts Hunan Province. The receiver operator characteristic (ROC)...