A5019056298- Pancreatic and Hepatic Oncology Research
- Pancreatitis Pathology and Treatment
- Gallbladder and Bile Duct Disorders
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Renal cell carcinoma treatment
- Cancer Genomics and Diagnostics
- RNA modifications and cancer
- Neuroendocrine Tumor Research Advances
- Reconstructive Facial Surgery Techniques
- Reconstructive Surgery and Microvascular Techniques
- Particle physics theoretical and experimental studies
- MicroRNA in disease regulation
- Facial Nerve Paralysis Treatment and Research
- Cancer Immunotherapy and Biomarkers
- High-Energy Particle Collisions Research
- Cancer-related molecular mechanisms research
- Quantum Chromodynamics and Particle Interactions
- Gastric Cancer Management and Outcomes
- Immune cells in cancer
- Ferroptosis and cancer prognosis
- Nanoplatforms for cancer theranostics
- Pediatric Hepatobiliary Diseases and Treatments
- Colorectal Cancer Screening and Detection
- Enhanced Recovery After Surgery
- Thermodynamic and Exergetic Analyses of Power and Cooling Systems
Shanghai Jiao Tong University
2009-2025
Ruijin Hospital
2013-2025
State Key Laboratory of Oncogene and Related Genes
2020-2024
China University of Petroleum, Beijing
2024
Fujian University of Traditional Chinese Medicine
2024
Minjiang University
2024
University of Pennsylvania
2018
Medical University of South Carolina
2013
Deutsches Herzzentrum der Charité
2010-2012
Tsinghua University
2009
Robot-assisted pancreaticoduodenectomy (RPD) has been reported to be safe and feasible. As a new technique, RPD learning curve similar that of other types minimally invasive pancreatic surgery such as laparoscopic pancreaticoduodenectomy. To our knowledge, no reports exist on the outcomes open (OPD) after curve.To analyze evaluate actual advantages RPD.Between May 2010 December 2018, 450 patients underwent in Shanghai Ruijin Hospital affiliated with Jiaotong University Shanghai, China,...
We aimed to describe our experience and the learning curve of 450 cases robot-assisted pancreaticoduodenectomy (RPD) optimize surgical process so that findings can be useful for surgeons starting perform RPD.Robotic systems were first introduced 20 years ago. Pancreaticoduodenectomy (PD) is a challenging surgery because its technical difficulty. RPD may overcome some these difficulties.The medical records patients who underwent between May 2010 December 2018 at Shanghai Ruijin Hospital...
Objective: To evaluate the effect of perioperative dexamethasone on postoperative complications after pancreaticoduodenectomy. Background: The glucocorticoid has been shown to improve outcomes in surgical patients, but its effects pancreaticoduodenectomy are unclear. Methods: This multicenter, double-blind, randomized controlled trial was conducted four Chinese high-volume pancreatic centers. Adults undergoing elective were receive either 0.2 mg/kg or a saline placebo as an intravenous bolus...
Pancreatic cancer (PC) is one of the most aggressive cancers presenting with high rates invasion and metastasis, unfavorable prognoses. The current study aims to investigate whether EZH2/miR-139-5p axis affects epithelial-mesenchymal transition (EMT) lymph node metastasis (LNM) in PC, mechanism how EZH2 regulates miR-139-5p. Human PC adjacent normal tissues were collected determine expression miR-139-5p, their relationship clinicopathological features PC. cell line was selected, treated...
This article describes and evaluates an organic Rankine cycle (ORC) for a waste heat recovery system by both theoretical experimental studies. Theoretical analysis of several working fluids shows that efficiency is very sensitive to evaporating pressure, but insensitive expander inlet temperature. Second law was carried out using R600a as fluid flow hot air source, which not isothermal, along the evaporator. The result discloses evaporator's internal external entropy generation main source...
Abstract Background Robotic-assisted minimally invasive surgery is associated with worse oncologic outcomes for some but not other types of cancers. We conducted a propensity score-matched analysis to compare robotic-assisted laparoscopic (RPD) vs. open pancreatoduodenectomy (OPD) pancreatic ductal adenocarcinoma (PDAC). Methods Treatment-naïve PDAC patients undergoing either RPD or OPD at our hospital between January 2013 and December 2017 were included. Propensity score matching was ratio...
Objective: To assess short-term and long-term outcomes following robotic enucleation (REn) of tumors in the proximal pancreas. Background: Despite advantages preserving function via pancreatic enucleation, controversies persist, since this can be associated with severe complications, such as clinically relevant postoperative fistula, especially when performed near main duct. The safety efficacy REn context remain largely unknown. Methods: A retrospective analysis was all patients who...
Abstract Background Immunotherapy has emerged as a potent clinical approach for cancer treatment, but only subsets of patients can benefit from it. Targeting lactate metabolism (LM) in tumor cells method to potentiate anti-tumor immune responses represents promising therapeutic strategy. Methods Public single-cell RNA-Seq (scRNA-seq) cohorts collected who received immunotherapy were systematically gathered and scrutinized delineate the association between LM response. A novel LM-related...
Recent studies have acknowledged the critical roles played by long non-coding RNAs (lncRNAs) in development and progression of pancreatic cancer. Therefore, present study aimed to elucidate mechanism underlying on how LINC01133 regulates Wnt signaling pathway A microarray-based gene expression analysis was performed identify differentially expressed lncRNAs In addition, ectopic assays, knockdown experiments reporter assays were conducted clarify role cancer understand interaction between...
Objective: This study aimed to characterize postpancreatectomy acute pancreatitis (PPAP) after pancreaticoduodenectomy (PD) in a high-volume center. Background: The International Study Group for Pancreatic Surgery (ISGPS) has recently proposed new definition and grading scale of PPAP, but specific studies are lacking. Methods: Patients who underwent PD from 2020 2021 were retrospectively reviewed. PPAP was defined based on the definition: sustained elevation serum amylase levels least first...
Abstract Although Knight’s (J Stud High Educ 8(1):5–31, 2004) definition of internationalization is widely cited, it often criticized as western-centered and may not be suitable for non-western contexts. This study explores the perspectives critical reflections on concept Chinese graduate students at a Hong Kong university. Findings highlight differences in ideas practices higher education between western countries, well challenges brought about by COVID- 19 pandemic changing geopolitics....
This study aimed to compare the short-term outcomes of open and robotic-assisted distal pancreatectomy (ODP RDP) for benign low-grade malignant tumors.The patients who underwent RDP ODP or pancreatic tumors at our center were included. After PSM a 1:1 ratio, perioperative variations in two cohorts compared.After PSM, 219 cases recorded. The cohort showed advantages operative duration [120 (90-150) min vs 175 (130-210) min, P < 0.001], estimated blood loss [50 (30-175) ml 200 (100-300) ml,...
This study aimed to investigate the clinical significance and risk factors of postoperative pancreatic fistula (POPF) after post-pancreatectomy acute pancreatitis (PPAP) in patients who underwent pancreaticoduodenectomy (PD).
Abstract Objective To identify factors associated with increased gingival inflammation in adults systemic sclerosis ( SS c, scleroderma). Methods In this cross‐sectional study, forty‐eight c received assessment of using Löe and Silness index LSGI ), measurement oral aperture evaluation manual dexterity to perform hygiene the Toothbrushing Ability Test, as well completion an health‐related questionnaire. Results Three explanatory variables final multiple predictor models for outcome were...
Epithelial-to-mesenchymal transition (EMT) is tightly associated with the invasion and metastasis of pancreatic cancer rapid progression poor prognosis. Notably, gene alternative splicing (AS) event plays a critical role in regulating cancer. Therefore, this study aims to identify EMT-related AS cancer.The sets, transcriptomes, matched clinical data were obtained from MSigDB, The Cancer Genome Atlas (TCGA), International Consortium (ICGC), Gene Expression Omnibus (GEO) databases. Key events...