Wei He

ORCID: 0000-0003-2812-4331
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About
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Research Areas
  • Genomics and Phylogenetic Studies
  • Microbial Community Ecology and Physiology
  • Potato Plant Research
  • Polyamine Metabolism and Applications
  • Plant Pathogens and Resistance
  • Aquaculture disease management and microbiota
  • Amino Acid Enzymes and Metabolism
  • Probiotics and Fermented Foods
  • Rice Cultivation and Yield Improvement
  • Plant Molecular Biology Research
  • Protist diversity and phylogeny
  • Crop Yield and Soil Fertility
  • Plant nutrient uptake and metabolism
  • Plant Physiology and Cultivation Studies
  • Vibrio bacteria research studies
  • Legume Nitrogen Fixing Symbiosis
  • Plant Water Relations and Carbon Dynamics
  • Circular RNAs in diseases
  • Agronomic Practices and Intercropping Systems
  • Polar Research and Ecology
  • Protein Hydrolysis and Bioactive Peptides
  • Microbial Natural Products and Biosynthesis
  • MicroRNA in disease regulation
  • Identification and Quantification in Food
  • Microbial Metabolism and Applications

The Affiliated Yongchuan Hospital of Chongqing Medical University
2025

Chongqing Medical University
2025

Ningbo University
2025

Hohai University
2021-2024

Anhui Agricultural University
2022-2024

Sichuan Academy of Agricultural Sciences
2016-2024

Beijing Union University
2024

Sichuan Agricultural University
2020-2024

Children's Hospital of Fudan University
2024

China Agricultural University
2014-2023

Genome-scale phylogenetic analysis based on core gene sets is routinely used in microbiological research. However, the techniques are still not approachable for individuals with little bioinformatics experience. Here, we present EasyCGTree, a user-friendly and cross-platform pipeline to reconstruct genome-scale maximum-likehood (ML) tree using supermatrix (SM) supertree (ST) approaches.EasyCGTree was implemented Perl programming languages built collection of published reputable programs. All...

10.1186/s12859-023-05527-2 article EN cc-by BMC Bioinformatics 2023-10-14

Increasing evidence indicates that gut microbiota may play a key role in vaccination immunity. Here, we investigate whether the human and metabolic function correlate with BBIBP-CorV vaccine response. A total of 207 participants who received are enrolled. The microbiome functions investigated using metagenomic sequencing metabolomic assays. We find is accompanied by altered composition functional pathways, its profiles levels short-chain fatty acids (SCFAs) much higher high antibody response...

10.1016/j.xcrm.2022.100752 article EN cc-by-nc-nd Cell Reports Medicine 2022-09-13

The families Paracoccaceae and Roseobacteraceae comprise metabolically, phenotypically genotypically diverse members, their descriptions rely heavily on 16S rRNA gene analysis. Hundreds of genera have been reported within the two misclassifications a reoccurring problem, even when taxonomies established based genome-scale phylogenetic reconstructions. In this study, we conducted comprehensive phylotaxonomic assessment four ubiquitous sets, bac120 (120 genes in Bacteria), rhodo268 (268 ‘...

10.1099/ijsem.0.006156 article EN INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY 2023-11-16

Background Tephritid fruit flies in the genus Bactrocera are of major economic significance agriculture causing considerable loss to and vegetable industry. Currently, there is no ideal control program. Molecular means an effective method for pest at present, but genomic or transcriptomic data members this remains limited. To facilitate molecular research into reproduction development mechanisms, finally on these pests, extensive transcriptome oriental fly dorsalis was produced using Roche...

10.1371/journal.pone.0036463 article EN cc-by PLoS ONE 2012-05-03

Summary African cultivated rice ( Oryza glaberrima Steud.) was domesticated from its wild progenitor species barthii ) about 3000 years ago. Seed shattering is one of the main constraints on grain production in rice, which causes severe losses during harvest. By contrast, Asian sativa displays greater resistance to seed shattering, allowing higher production. A better understanding regulation would help improve harvesting efficiency rice. Here, we report map‐based cloning and...

10.1111/pbi.14004 article EN cc-by-nc-nd Plant Biotechnology Journal 2023-01-07

During farm-to-consumer transport, a live supply chain can aid in maintaining the quality of whiteleg shrimp (Penaeus vannamei). However, changes muscle and gut microbiota their interactions are poorly understood. Here, we investigated dynamics cumulative survival, quality, key phases chain: post-harvest, post-transport, post-respite, simulated sales [ambient temperature (AT; 29 °C ± 0.3 °C); low (LT; 23 °C)]. The results suggest that among various stages, highest mortality (12%) occurred...

10.3390/ani15101431 article EN cc-by Animals 2025-05-15

Our aim was to demonstrate the significance of miRNA, lncRNA, and circRNA in transformation human bronchial epithelial cells induced by benzo(a)pyrene (BaP), investigate their regulatory networks. Hierarchical clustering, gene ontology (GO) analysis, Kyoto Encyclopedia Genes Genomes (KEGG) analysis network regulation were used analyze high-throughput sequencing results cell line BEAS-2B BaP-transformed (BEAS-2B-T). 76,191,786 3,431differentially-expressed mRNA detected, respectively; 43 48...

10.2131/jts.43.281 article EN The Journal of Toxicological Sciences 2018-01-01

Vibrio parahaemolyticus causes serious seafood-borne gastroenteritis and death in humans. Raw seafood is often subjected to post-harvest processing low-temperature storage. To date, very little information available regarding the biological functions of cold shock proteins (CSPs) survival bacterium. In this study, we determined complete genome sequence V. CHN25 (serotype: O5:KUT). The two main CSP-encoding genes (VpacspA VpacspD) were deleted from bacterial genome, comparative transcriptomic...

10.1186/s12864-017-3784-5 article EN cc-by BMC Genomics 2017-06-05

The aim of this study was to explore the effects different density treatments on potato spatial distribution and yield in spring fall. Plant influenced composition, horizontal vertical distances between tubers, position tuber weights. results indicated that: (1) Spring had a convex quadratic curve relationship with density, highest value observed at 15.75 × 104 tubers per hectare. However, fall potatoes showed linear plant 18 hectare; (2) Density greater influence weight fruit number single...

10.3389/fpls.2016.00365 article EN cc-by Frontiers in Plant Science 2016-04-08

Hepatitis B virus (HBV) infection is the main trigger of hepatocellular carcinoma (HCC). Circular RNA plays an indispensable role in cancer development, and this study aimed to disclose function mechanism circ_0027089 HBV-related HCC. The expression levels circ_0027089, miR-136-5p nucleus accumbens associated protein 1 (NACC1) mRNA were measured by quantitative real-time PCR, level NACC1 was detected western blot. For functional analyses, cell proliferation assessed counting kit-8 assay...

10.1097/cad.0000000000001211 article EN Anti-Cancer Drugs 2021-08-19
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