A5101978424- Mercury impact and mitigation studies
- Heavy metals in environment
- Environmental Toxicology and Ecotoxicology
- Microbial bioremediation and biosurfactants
- Chromium effects and bioremediation
- Toxic Organic Pollutants Impact
- Cellular transport and secretion
- Heavy Metal Exposure and Toxicity
- Pesticide and Herbicide Environmental Studies
- Nanoparticle-Based Drug Delivery
- Analytical chemistry methods development
- Advanced Glycation End Products research
- Mesoporous Materials and Catalysis
- Nanoparticles: synthesis and applications
- Dendrimers and Hyperbranched Polymers
- Per- and polyfluoroalkyl substances research
- Pharmaceutical and Antibiotic Environmental Impacts
- Microplastics and Plastic Pollution
- Effects and risks of endocrine disrupting chemicals
- Erythrocyte Function and Pathophysiology
- Connexins and lens biology
- Mass Spectrometry Techniques and Applications
- Lipid Membrane Structure and Behavior
- Phytochemicals and Medicinal Plants
- Catalytic Processes in Materials Science
University of Newcastle Australia
2015-2023
Cooperative Research Centre for Contamination Assessment and Remediation of the Environment
2015-2020
University of South Australia
2014-2015
University of New England
2009
Centre for Cellular and Molecular Biology
2005-2007
Summary Parabens are used as antimicrobial preservative agent in many commercial products including cosmetics and pharmaceuticals. Weak oestrogenic antiandrogenic activities have been attributed to parabens vitro vivo studies. In this study, human spermatozoa were exposed different concentrations of an equimolar paraben mixture containing methyl, ethyl, propyl butylparaben well methylparaben alone at a concentration that is typical commercially available vaginal lubricants. The induction...
Benzo[a]pyrene (BaP), a polycyclic aromatic hydrocarbon (PAH), is one of the major environmental pollutants that causes mutagenesis and cancer. BaP has been shown to accumulate in phytoplankton zooplankton. We have studied localization aggregation Chlorella sp., microalga primary producers food chain, using fluorescence confocal microscopy lifetime imaging with phasor approach characterize location cell. Our results show accumulates lipid bodies sp. there Förster resonance energy transfer...
Abstract Core-shell mesoporous silica nanoparticles (MSN) have recently emerged as a promising drug delivery system that can be used for loading large quantities of different types drugs or creating stimuli responsive system. However, achieving this unique core-shell morphology with smaller size, high specific surface area, and pore volume is highly challenging. In study, we report the synthesis MSN using triple surfactant assisted soft-templating approach. We show morphological textural...
A Gram-positive bacterium, Microbacterium esteraromaticum MM1 able to degrade organophosphorus pesticides such as fenamiphos and malathion, also possessed the ability high molecular weight polycyclic aromatic hydrocarbon (PAH), pyrene (Pyr) benzo[a]pyrene (BaP). The strain degraded 98.7% of initially spiked 100 mg L−1 within 15 days from M9 mineral salts medium (pH 7.0) with 0.1% glucose. At optimal pH 7.0, 57.81% (100 L−1) was sole carbon source. In order determine influence sources...
Mesoporous silica-based nanoparticles (MSNs) have gained rapid interest as a drug delivery system (DDS) and demonstrated their versatility in delivering drugs for the treatment of various cancers. However, loading efficiency MSNs is low usually improved by improving textural properties through complicated synthesis methods or post modification surface that can result loss area modify its release properties. In this study, we report direct single-step with unique egg-yolk core-shell...
Neuronal calcium sensor-1 (NCS-1), a Ca(2+)-binding protein of the sensor family, modulates various functions in intracellular signaling pathways. The N-terminal glycine this is myristoylated, which presumably necessary for its physiological functions. In order to understand structural role myristoylation and on conformational stability, we have investigated equilibrium unfolding refolding myristoylated non-myristoylated NCS-1. these two forms NCS-1 presence best characterized by five-state...
This study aimed to identify arsenic resistant mechanisms in As‐resistant purple nonsulfur bacteria (PNSB) by screening them for presence of As‐resistance genes and related enzymes. Resistance As(III) As(V) four PNSB determined terms median inhibition concentration (IC 50 values) were the order strains Rhodopseudomonas palustris C1 > R. AB3 Rubrivivax benzoatilyticus C31 L28 which corresponded these bacteria. The strain showed all As‐marker genes; ars C, M, aio A, acr 3, while A was not...