About
Contact & Profiles
A5102825739
Research Areas
- Lymphatic System and Diseases
- Cerebrospinal fluid and hydrocephalus
- Neuroinflammation and Neurodegeneration Mechanisms
Yale University
2024
Meningeal lymphatic vessels (MLVs) promote tissue clearance and immune surveillance in the central nervous system (CNS). Vascular endothelial growth factor-C (VEGF-C) regulates MLV development maintenance has therapeutic potential for treating neurological disorders. Herein, we investigated effects of VEGF-C overexpression on brain fluid drainage ischemic stroke outcomes mice. Intracerebrospinal administration an adeno-associated virus expressing mouse full-length (AAV-mVEGF-C) increased CSF...
10.1084/jem.20221983
article
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The Journal of Experimental Medicine
2024-03-05
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