A5058157524- Traumatic Brain Injury Research
- Cardiac Arrest and Resuscitation
- Traumatic Brain Injury and Neurovascular Disturbances
- Cardiovascular Effects of Exercise
- Advanced Neuroimaging Techniques and Applications
- Resilience and Mental Health
- Sports injuries and prevention
- Injury Epidemiology and Prevention
- Functional Brain Connectivity Studies
- Trauma and Emergency Care Studies
- Meta-analysis and systematic reviews
- Diverse Approaches in Healthcare and Education Studies
- Radiation Dose and Imaging
- Musculoskeletal pain and rehabilitation
- Dementia and Cognitive Impairment Research
- Advanced MRI Techniques and Applications
- Health, Environment, Cognitive Aging
- COVID-19 and Mental Health
- Sport Psychology and Performance
- Gender Roles and Identity Studies
- Health disparities and outcomes
- Neonatal and fetal brain pathology
- Delphi Technique in Research
- Sports Performance and Training
- Cognitive Functions and Memory
Medical College of Wisconsin
2018-2025
University of Missouri
2024
University of Missouri–Kansas City
2024
United States University
2023
University of California, San Diego
2023
Harvard University
2023
University of Pittsburgh Medical Center
2023
The Ohio State University Wexner Medical Center
2023
University of California, San Francisco
2023
Seattle University
2023
Abstract Sex or gender differences in the risk of Alzheimer's disease and related dementias (ADRD) differ by world region, suggesting that there are potentially modifiable factors for intervention. However, few epidemiological clinical ADRD studies examine sex differences; even fewer evaluate context risk. The goals this perspective to: (1) provide definitions gender, biologic sex, sexual orientation. limitations examining these as binary variables; (2) an overview what is known with regard...
Many level I trauma center patients experience clinical sequelae at 1 year following traumatic brain injury (TBI). Longer-term outcome data are needed to develop better monitoring and rehabilitation services.To examine functional recovery, TBI-related symptoms, quality of life from 5 years postinjury.This cohort study enrolled across 18 US centers between 2014 2018. Eligible participants were within 24 hours followed up postinjury. Data analyzed January 2023.Mild TBI (mTBI), moderate-severe...
Traumatic brain injury (TBI) may be a chronic condition carrying risk of future sequelae; few prospective studies examine long-term postinjury outcomes. We examined the prevalence functional, cognitive, and psychiatric change outcomes from 1 to 7 years postinjury.
Objectives To examine the relationships among self-reported sport-related concussion (SRC) history and current health-promoting behaviours (exercise frequency, diet quality sleep duration) with measures of brain health (cognitive function, symptoms depression anxiety emotional–behavioural dyscontrol) in former NFL players. Methods In this cross-sectional study, a questionnaire was sent to Respondents reported SRC (categorical: 0; 1–2; 3–5; 6–9; 10+ concussions), number moderate-to-vigorous...
Although some studies have observed a relationship between age of first exposure (AFE) to American football and long-term outcomes, recent findings in collegiate athletes did not observe AFE more intermediate outcomes at early adulthood. This, however, requires independent replication.
OBJECTIVE Sport-related concussion (SRC) has become a major public health concern. Prolonged recovery after SRC, named postconcussion syndrome (PCS), been associated with several biopsychosocial factors, yet the role of both family and personal psychiatric histories requires investigation. In cohort concussed high school athletes, authors examined role(s) in risk developing PCS. METHODS A retrospective study 154 athletes complete documentation symptom resolution or persistence at 6 weeks was...
The empirical identification of risk factors associated with sport-related concussion (SRC) may improve the management student-athletes. current study attempted to identify and quantify bio-cognitive sustaining a SRC.Cross-sectional ambispective study; level evidence, 3. Neurocognitive testing 12,320 middle school, high school collegiate athletes was completed at preseason baseline post-SRC. Univariate multivariable logistic regressions were used determine which pre-injury variables...
<h3>Importance</h3> Heterogeneity across patients with traumatic brain injury (TBI) presents challenges for clinical care and intervention design. Identifying distinct phenotypes of TBI soon after may inform patient selection precision medicine trials. <h3>Objective</h3> To investigate whether neurobehavioral can be identified 2 weeks to characterize the degree which early are associated 6-month outcomes. <h3>Design, Setting, Participants</h3> This prospective cohort study included...
ABSTRACT Purpose This study aimed to estimate prevalence of mild cognitive impairment (MCI) and dementia diagnoses in former National Football League (NFL) players ≥50 yr old examine the relationships among these an array predictors long-term brain health. Methods A cross section NFL ( n = 922; mean ± SD age, 64.8 8.9 yr) completed a questionnaire. Prevalence self-reported medical MCI was reported alongside U.S. population estimates across 5-yr age intervals (e.g., 60–64 yr). ratios (PR)...
To identify subgroups of former National Football League (NFL) players using latent profile analysis (LPA) and examine their associations with total years participation (TYP) self-reported lifetime sport-related concussion history (SR-CHx).Former NFL (N=686) aged 50-70 years, an average 18.0 TYP (±4.5) completed a questionnaire. SR-CHx distributions included: low (0-3; n=221); intermediate (4-8; n=209) high (9+; n=256). LPA measures Quality Life in Neurological Disorders Emotional-Behavioral...
Studies have demonstrated associations between cumulative concussion and repetitive head impact exposure (RHI) via contact sports with white matter (WM) alterations later in life. The course of WM changes associated earlier the lifespan are unclear. This study investigated (WM hyperintensity [WMH] volume microstructural changes) RHI from adolescence to early midlife, as well interaction age-cohort (i.e., adolescent/young adult compared midlife athlete cohorts) on outcomes. Participating...
The ImPACT (Immediate Post-Concussion Assessment and Cognitive Testing) neurocognitive testing battery is a widely used tool for the assessment management of sports-related concussion. Research on stability in high school athletes at 1- 2-year intervals have been inconsistent, requiring further investigation. We documented 1-, 2-, 3-year test-retest reliability repeated baseline assessments sample athletes, using multiple statistical methods examining stability.A total 1,510 completed...
There is concern that previous concussion and contact-sport exposure may have negative effects on brain structure function. Accurately quantifying complicated by the fact multiple definitions exist, with recent allowing for diagnosis based presence of symptoms alone (Concussion in Sport Group criteria; CISG) rather than acute injury characteristics such as alterations mental status (American Congress Rehabilitation Medicine ACRM). The goals current work were to determine gray matter clinical...
Repetitive head impact (RHI) exposure has been associated with differences in brain structure among younger active athletes, most often within the hippocampus. Studies of former athletes at early-midlife are limited. We investigated association between RHI and gray matter (GM) structure, as well moderating factors, early-midlife. Former collegiate football players (n = 55; age 37.9 + 1.5 years) completed magnetic resonance imaging to quantify GM morphometry extensive structured interviews...
Abstract Objective Characterize the levels of various metrics repetitive head impacts (RHI) in contact (CS) and non-contact (NCS) sport athletes determine extent to which they are associated with fluid cognition. Methods Collegiate-aged (n = 176) completed semi-structured interviews about participation sport. RHI was operationalized based on current (CS/NCS), cumulative number years participation, age at first exposure (AFE), recently proposed traumatic encephalopathy syndrome (TES)...