Sen Xu

ORCID: 0000-0003-2851-4284
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About
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Research Areas
  • Cryptographic Implementations and Security
  • Chaos-based Image/Signal Encryption
  • Physical Unclonable Functions (PUFs) and Hardware Security
  • Treatment of Major Depression
  • Cryptography and Data Security
  • Cryptography and Residue Arithmetic
  • Intracerebral and Subarachnoid Hemorrhage Research
  • Coding theory and cryptography
  • Advanced Computational Techniques and Applications
  • Neurosurgical Procedures and Complications
  • Security and Verification in Computing
  • Nicotinic Acetylcholine Receptors Study
  • Spinal Hematomas and Complications
  • Forest ecology and management
  • Anesthesia and Sedative Agents
  • Remote Sensing and LiDAR Applications
  • Diabetes and associated disorders
  • Computational and Text Analysis Methods
  • Angiogenesis and VEGF in Cancer
  • Fibromyalgia and Chronic Fatigue Syndrome Research
  • Network Packet Processing and Optimization
  • Genetic factors in colorectal cancer
  • Energetic Materials and Combustion
  • Musculoskeletal Disorders and Rehabilitation
  • Heme Oxygenase-1 and Carbon Monoxide

Zhejiang Chinese Medical University
2023-2025

Binzhou University
2025

Xinjiang New Energy Research Institute (China)
2025

Hangzhou Medical College
2024-2025

Zhejiang Provincial People's Hospital
2024-2025

Binzhou Medical University
2025

Fudan University
2025

Zhongshan Hospital
2025

Shanghai Research Institute of Chemical Industry
2025

Tongji Hospital
2023-2024

Homologous recombination deficiency (HRD) is prevalent in cancer, sensitizing tumor cells to poly (ADP-ribose) polymerase (PARP) inhibition. However, the impact of HRD and related therapies on microenvironment (TME) remains elusive. Our study generates single-cell gene expression T cell receptor profiles, along with validatory multimodal datasets from >100 high-grade serous ovarian cancer (HGSOC) samples, primarily a phase II clinical trial (NCT04507841). Neoadjuvant monotherapy PARP...

10.1016/j.cell.2024.06.013 article EN cc-by Cell 2024-07-05

Natural broadleaf forests (NBFs) are the most abundant zonal vegetation type in subtropical regions. Understanding mechanisms influencing stand productivity NBFs is important for developing “nature-based” solutions climate change mitigation. However, minimal research has captured effects of nonlinearities and feature interactions that often have nonlinear impacts on factors. To address this gap, we used continuous forest inventory data, a machine learning model was constructed. Subsequently,...

10.3390/f16010095 article EN Forests 2025-01-08

In order for active distribution network operators to carry out power business such as load forecasting without meter reading rights, the author proposes a research on data analysis and privacy protection based federated learning. The learning framework industry user by selecting weather time factors correlation of load. On this basis, constructed an dataset established model Long Short Term Time Series Network (LSTNet). At same time, FedML was used establish sub results indicate that:...

10.12694/scpe.v26i2.3893 article EN Scalable Computing Practice and Experience 2025-02-10

Background Acetaminophen (APAP) can be used for pain relief and fever alleviation, the overdose of which, however, may lead to accumulation N-acetyl-p-benzoquinone imine (NAPQI), inducing oxidative stress liver damage. The natural compound SMND-309 has been shown have hepatoprotective effects potential antioxidant activity. However, its ability alleviate acetaminophen-induced acute injury (AILI) not elucidated. Objective To explore protective effect against AILI mechanism. Methods model was...

10.1371/journal.pone.0310879 article EN cc-by PLoS ONE 2025-03-31

Cardiac surgery often results in significant postoperative pain, which can lead to complications and prolonged recovery. Pain depression are closely linked, with effective pain management potentially reducing the risk of depression. Combining sufentanil, an opioid, esketamine, a medication both analgesic antidepressant effects, may improve control mood patients. While promising other surgeries, their effects cardiac remain unclear. This study explores how sufentanil esketamine work together...

10.21037/cdt-24-312 article EN Cardiovascular Diagnosis and Therapy 2025-04-01

Based on the continuous inventory data of forest resources in Zhejiang Province 2019 and 2021, we used statistical methods such as polynomial regression to analyze impacts topography spatial structure average annual diameter at breast height (DBH) growth main pioneer tree species natural broad-leaved mixed forests. The results showed that DBH

10.13287/j.1001-9332.202402.036 article EN PubMed 2024-02-01

Abstract It is well established that sevoflurane exposure leads to widespread neuronal cell death in the developing brain. Adenosine deaminase acting on RNA-1 (ADAR1) dependent adenosine-to-inosine (A-to-I) RNA editing dynamically regulated throughout brain development. The current investigation designed interrogate contributed role of ADAR1 developmental neurotoxicity. Herein, we provide evidence show priming triggers pyroptosis, apoptosis and necroptosis (PANoptosis), elicits release...

10.1007/s10565-024-09905-1 article EN cc-by Cell Biology and Toxicology 2024-07-25

The aim is to investigate the relationship between serum coagulation parameters (PT, APTT, D-D and FDP) before hospitalization recurrence of chronic subdural hematoma (CSDH). 236 patients with CSDH who were diagnosed for first time had complete medical records followed up at least 90 days. Fifty (21.2%) relapsed. Univariate analysis was conducted including general data, imaging data test results. Serum detected all patients. study identified several factors that exhibited a significant...

10.1007/s11010-024-05019-8 article EN cc-by Molecular and Cellular Biochemistry 2024-05-14

Power analysis against elliptic curve digital signature algorithm (ECDSA) has been researched for many years. Nowadays traditional methods like simple power (SPA) or differential (DPA) are no longer effective secure ECDSA implementations. In this situation, Howgrave-Graham and Smart introduced a new lattice-based attack to recover the secret key of Digital Signature Algorithm (DSA) even if only several bits nonce revealed. Later Nguyen Shparlinski extended ECDSA. paper, we further extend SM2...

10.1109/cis.2017.00061 article EN 2021 17th International Conference on Computational Intelligence and Security (CIS) 2017-12-01

Semaphorins constitute a diverse family of widely expressed transmembrane, diffusible, and GPI-linked proteins with versatile physiologic functions in orchestrating nerve system development, immune homeostasis, angiogenesis, cell metabolism. Accumulating evidence highlights semaphorins as essential regulators tumorigenesis by coordinating the cell-cell communications tumor microenvironment. Semaphorin 4C (SEMA4C) is member fourth class high affinity to Plexin-B2 its interplay cancer has long...

10.1051/vcm/2023002 article EN cc-by Visualized Cancer Medicine 2023-01-01

Chosen-message pair Simple Power Analysis (SPA) attacks were proposed by Boer, Yen and Homma, are attack methods based on searches for collisions of modular multiplication. However, searching is difficult in real environments. To circumvent this problem, we propose the Clustering Attack (SPCA), which can automatically identify multiplication collision. The insignificant effects collision validated an Application Specific Integrated Circuit (ASIC) environment. After treatment with SPCA,...

10.1109/cc.2013.6520943 article EN China Communications 2013-05-01

Power analysis is a non-invasive attack against cryptographic hardware, which effectively exploits runtime power consumption characteristics of circuits. This paper proposes new model combines Hamming Distance and the based on template value in combinational logic circuit. The can describe sequential circuits those as well. be used to improve existing methods detect information leakage consumption. Experimental results show that, compared CPA(Correlation Analysis) method, our proposed adopt...

10.1109/cc.2015.7084387 article EN China Communications 2015-01-01

As an important operation, modular inversion is crucial for high-performance public key cryptosystems (PKC), especially in Elliptic curve-based schemes over prime fields. Both security and efficiency must be considered a specific implementation. Straightforward implementation leaks side channel information which can used breaking curve signature algorithm (ECDSA) through combination attack. Modular also the most time-consuming operation has impact on performance. Therefore, efficient...

10.1109/cis.2017.00122 article EN 2021 17th International Conference on Computational Intelligence and Security (CIS) 2017-12-01

In order to clarify the combustion-supporting mechanism of fluoropolymers, this work focuses on atomic details oxidation Al nanoparticles with fluoropolymers and O 2 , using reactive dynamics simulations.

10.1039/d3nj02819d article EN New Journal of Chemistry 2023-01-01

Background: Intracerebral hemorrhage (ICH) comprises primary and secondary injuries, the latter of which induces increased inflammation apoptosis is more severe. Activating transcription factor 6 (ATF6) a type-II transmembrane protein in endoplasmic reticulum (ER). ATF6 target genes could improve ER homeostasis, contributes to cryoprotection. Hence, we predict that will have protective effect on brain tissue after ICH. Method: The ICH rat model was generated through autologous blood...

10.18632/aging.205737 article EN cc-by Aging 2024-04-10

Background The causality of autoimmune diseases with frailty has not been firmly established. We conducted this Mendelian randomization (MR) study to unveil the causal associations between frailty. Methods A MR analyses were performed explore relationships disease and frailty, using summary genome-wide association statistics. Results Through a comprehensive meticulous screening process, we incorporated 46, 7, 12, 20, 5, 53 single nucleotide polymorphisms (SNPs) as instrumental variables...

10.3389/fendo.2024.1364368 article EN cc-by Frontiers in Endocrinology 2024-08-27
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