A5085592374- Bone and Joint Diseases
- Oceanographic and Atmospheric Processes
- Magnesium Alloys: Properties and Applications
- RNA modifications and cancer
- Orthopaedic implants and arthroplasty
- Bone Tissue Engineering Materials
- Crystallization and Solubility Studies
- Cancer Cells and Metastasis
- Tropical and Extratropical Cyclones Research
- X-ray Diffraction in Crystallography
- Extracellular vesicles in disease
- Osteoarthritis Treatment and Mechanisms
- Plant Stress Responses and Tolerance
- Aluminum Alloys Composites Properties
- Bone health and treatments
- GABA and Rice Research
- Ocean Waves and Remote Sensing
- Higher Education and Teaching Methods
- Cancer-related molecular mechanisms research
- Advanced Computational Techniques and Applications
- Corrosion Behavior and Inhibition
- Hip disorders and treatments
- Crop Yield and Soil Fertility
- Heavy Metal Exposure and Toxicity
- Biofuel production and bioconversion
Nanyang Medical College
2020-2025
National Center for Climate Change Strategy and International Cooperation
1997-2024
Affiliated Zhongshan Hospital of Dalian University
2015-2024
China Meteorological Administration
2016-2024
Zhengzhou University
2020-2024
University of Jinan
2014-2023
Central South University
2006-2023
Northwest A&F University
2019-2022
Hebei General Hospital
2016-2022
Xuzhou Medical College
2022
N6 -methyladenosine (m6 A) reader protein plays an important role in trichome morphology, developmental timing and morphogenesis Arabidopsis. However, the function of m6 A readers plant-microbe interaction remains unclear. Here, a Malus YTH-domain family MhYTP2 was initially characterized as reader. overexpression increased mRNA modification level translation efficiency. The exon regions appeared to destabilize mRNAs, whereas untranslated positively correlated with associated abundance....
Visceral adiposity index (VAI) is a novel sex-specific for visceral adipose function; however the association between VAI and hyperuricemia in China unknown. We aimed to investigate this association, also whether it was independent of metabolic health obesity phenotypes. 7632 adult subjects from Health Nutrition Survey 2009 were retained. Subjects categorized into four phenotypes based on cross-classification BMI status by two representative criteria. best predictors irrespective phenotypes,...
Transforming growth factor β1 (TGF‑β1) has been suggested to be a candidate cytokine in the field of bone tissue engineering. Cytokines serve important roles engineering, particularly repair damage; however, underlying molecular mechanisms remain unclear. In present study, effects TGF‑β1 on osteogenesis and motility hFOB1.19 human osteoblasts were demonstrated via phenotype gene expression cells. Additionally, role phosphatidylinositol 3‑kinase/protein kinase B/mammalian target rapamycin/S6...
Arid and semiarid apple producing areas suffer from severe alkalinity of soil, which strongly affects the yield quality apples. Dopamine (DA) is involved in metabolic activities response to abiotic stress plants. To detect effects exogenous DA application on adaption (Malus hupehensis) seedlings alkali as a protection oxidative stress, 0.1 mM was identified most suitable concentration by hydroponic culture. Further experimentation showed that growth photosynthesis were significantly...
Regeneration of long-bone segmental defects remains a challenge for orthopedic surgery. Current treatment options often require several revision procedures to maintain acceptable alignment and achieve osseous healing. A novel hollow tubular system utilizing magnesium-strontium (Mg-Sr) alloy with autogenous morselized bone filled inside repair was developed. To improve the corrosion biocompatible properties, two coatings, Ca-P Sr-P were prepared on surface implants. Feasibility applying these...
Drought seriously affects the yield and quality of apples. γ-aminobutyric acid (GABA) plays an important role in responses plants to various stresses. However, possible mechanism GABA drought response apple seedlings remain unknown. To explore effect on under stress, Malus hupehensis were treated with seven concentrations GABA, 15-day stress was observed. The results showed that 0.5 mM most effective at relieving stress. Treatment reduced relative electrical conductivity MDA content leaves...
BACKGROUND Knee osteoarthritis (KOA) is a common orthopedic condition with an uncertain etiology, possibly involving genetics and biomechanics. Factors like changes in chondrocyte microenvironment, oxidative stress, inflammation, immune responses affect KOA development. Early-stage treatment options primarily target symptom relief. Mesenchymal stem cells (MSCs) show promise for treatment, despite challenges. Recent research highlights microRNAs (miRNAs) within MSC-released extracellular...
Autoantibodies against tumor antigens are promising means for cancer diagnosis and prognosis. In this study, we applied a proteomic approach to identify proteins that commonly elicit humoral response in lung squamous carcinoma (LSC). Sera from 20 newly diagnosed patients with LSC matched healthy individuals were analyzed antibody-based reactivity separated by two-dimensional electrophoresis. triosephosphate isomerase (Tim) superoxide dismutase [Mn] (MnSOD) detected sera over 20% but none the...
Avascular necrosis of femoral head and nonunion is a major complication after the treatment displaced neck fracture in young adults. The purpose this study was to introduce new technique using biodegradable magnesium screws vascularised iliac grafting for Totally 19 patients with treated were retrospectively reviewed. steps included harvesting vascularized graft, fixing combined implantation. All followed an average 16 months (range: 8–24 months). Clinical radiological outcomes evaluated. In...
Porous tantalum metal with low elastic modulus is similar to cancellous bone. Reticulated vitreous carbon (RVC) can provide three-dimensional pore structure and serves as the ideal scaffold of coating. In this study, biocompatibility domestic porous was first successfully tested bone marrow stromal stem cells (BMSCs) in vitro for tissue repair vivo. We evaluated cytotoxicity RVC coating using BMSCs. The morphology, adhesion, proliferation BMSCs were observed via laser scanning confocal...
Nontraumatic osteonecrosis of the femoral head (NONFH) is a highly disabling orthopedic disease in young individuals. Plasminogen activator inhibitor 1 (PAI-1) has been reported to be positively associated with NONFH. We aimed investigate dysregulating PAI-1 bone marrow mesenchymal stem cells (BMMSCs) and vascular rabbit steroid-induced NONFH.To verify hypothesis that BMMSCs could promote thrombus formation paracrine manner, we collected exosomes from glucocorticoid-treated (GB-Exo)...
Hexavalent chromium [Cr(VI)] is an occupational carcinogen that accumulates in the lungs and causes lung injury even cancer. 36 SD male rats received inhalable intratracheal instillation of Cr(VI) (0.05, 0.25 mg Cr/kg) or same volume (3 ml/kg) normal saline weekly for 28 days (total 5 times). After exposure, half each group were sacrificed investigation, rest stopped exposure began to be self-repaired two weeks. Histopathology analyses revealed induced slight dilatation hemorrhage...
There is currently substantial interest in the identification of human tumor antigens for diagnosis and immunotherapy cancer. In our previous study, secretion character up‐regulation triosephosphate isomerase were observed lung squamous cell carcinoma, autoantibodies against peroxiredoxin 6 detected sera from over 25% patients, but none healthy controls. this was also found at higher levels patients. Up‐regulated further validated by enzyme‐linked immunosorbent assay an additional 61...