Xiaofang Hu

ORCID: 0000-0003-2859-2629
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About
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Research Areas
  • Immunotherapy and Immune Responses
  • Occupational Health and Safety Research
  • Immune Cell Function and Interaction
  • Phytochemicals and Antioxidant Activities
  • Phytochemistry and Biological Activities
  • Plant-based Medicinal Research
  • Infrastructure Resilience and Vulnerability Analysis
  • MicroRNA in disease regulation
  • Occupational exposure and asthma
  • Epigenetics and DNA Methylation
  • Endoplasmic Reticulum Stress and Disease
  • Essential Oils and Antimicrobial Activity
  • Dermatology and Skin Diseases
  • Immune cells in cancer
  • Risk and Safety Analysis
  • Bioactive Natural Diterpenoids Research
  • Supply Chain Resilience and Risk Management
  • Environmental and Social Impact Assessments
  • T-cell and B-cell Immunology
  • GDF15 and Related Biomarkers
  • Circular RNAs in diseases
  • Monoclonal and Polyclonal Antibodies Research
  • Advanced Biosensing Techniques and Applications
  • Allergic Rhinitis and Sensitization
  • Tea Polyphenols and Effects

Zhongda Hospital Southeast University
2025

Institute of Disaster Prevention
2024

Southern Medical University
2019

Zunyi Medical University
2018-2019

General Hospital of Shenyang Military Region
2012-2018

Shenyang 242 Hospital
2011

10.1016/j.trd.2024.104587 article EN Transportation Research Part D Transport and Environment 2025-01-01

To explore the effect of microRNA-132 heart failure and provide theoretical guidance for clinical treatment (HF).Peripheral blood was collected from HF patients. RT-qPCR used to determine expression. Mouse models were established. Color Doppler ultrasound utilized measure changes cardiac function. HE Masson staining applied observe pathological myocardium. After H9C2 cells transfected with microRNA-132, MTT assay employed detect stability cells. ELISA levels oxidative stress factors. Western...

10.1155/2018/3452748 article EN cc-by BioMed Research International 2018-01-01

ABSTRACT Osteosarcoma (OS) is the most common malignant tumor of bone. This paper aimed to explore mechanism macrophage polarization and glycolysis in OS. Gene expression microarray GSE42572 for OS was downloaded from GEO database validated TCGA‐SARC. CDKN2A cell lines normal human bone osteoblasts detected. Saos2 cells were transfected with siRNA‐CDKN2A, U2OS pcDNA3.4‐CDKN2A knock down or upregulate role behaviors. Extracellular acidification rate, oxygen consumption glycolysis‐related...

10.1096/fj.202401343rrr article EN The FASEB Journal 2025-04-07

The aim of present research is to analyze the detailed changes dendritic cells (DCs) induced by pidotimod(PTD). These impacts on DCs both bone marrow derived and established DC2.4 cell line were assessed with use conventional scanning electron microscopy (SEM), flow cytometry (FCM), transmission (TEM), cytochemistry assay FITC-dextran, bio-assay enzyme linked immunosorbent (ELISA). We demonstrated ability PTD induce DC phynotypic functional maturation as evidenced higher expression key...

10.4161/hv.20579 article EN Human Vaccines & Immunotherapeutics 2012-08-03

Abstract Flower teas are widely consumed across the world because of their beneficial health effects. The antioxidant activities methanol extracts from ten common flower in China were evaluated using four assays. total phenolic (TPCs) and flavonoid contents (TFCs) also investigated. Most these exhibited potent effects, which rosae rugosae flos exerted strongest effects Rosae highest TPC, while fragrans showed TFC. Correction analysis indicated that phenolics play a key role effect teas,...

10.1515/chem-2019-0091 article EN cc-by Open Chemistry 2019-10-16

IL-2 is a pleiotropic cytokine produced by T cell after antigen activation of and it so called growth factor. A large number documents suggest that Il-2 plays pivotal roles in the immune response now an approved drug being used for various kinds diseases such as cancer dermatitis. (1) The aim present exploration was to look at effect on structural, phenotypic functional maturation murine BMDCs. structural BMDCs under influence were evaluated light microscope flow cytometry (FCM). confirmed...

10.1080/21645515.2015.1009336 article EN cc-by Human Vaccines & Immunotherapeutics 2015-01-26

In the construction of prefabricated buildings, safety issues occur frequently, posing challenges to project progress and personnel safety. As a new trend in industry, complexity environment demands an update traditional management concepts. This study introduces concept resilience analyze develops WSR-4Rs framework for systematic evaluation The first combines WSR (Wuli-Shili-Renli) methodology with 4R theory construct index system Then, it uses Analytic Hierarchy Process (AHP) entropy...

10.3390/buildings14113459 article EN cc-by Buildings 2024-10-30

To address the uncertainty of influencing factors in measuring resilience subway stations to flood disasters, this study introduces Unascertained Measurement Theory assess against disasters. Initially, research involves a thorough examination and analysis past disaster incidents, which elucidates system its processes, thereby facilitating construction framework specific stations. Subsequently, measurement index is developed evaluate drawing upon relevant literature, levels are categorized...

10.3390/app142310930 article EN cc-by Applied Sciences 2024-11-25
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