Jean‐Charles Leblanc

ORCID: 0000-0003-2872-3414
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About
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Research Areas
  • Agricultural safety and regulations
  • Effects and risks of endocrine disrupting chemicals
  • Pesticide Residue Analysis and Safety
  • Nutritional Studies and Diet
  • Carcinogens and Genotoxicity Assessment
  • Toxic Organic Pollutants Impact
  • Consumer Attitudes and Food Labeling
  • Heavy metals in environment
  • Mercury impact and mitigation studies
  • Heavy Metal Exposure and Toxicity
  • Pesticide Exposure and Toxicity
  • Fatty Acid Research and Health
  • Meat and Animal Product Quality
  • Mycotoxins in Agriculture and Food
  • Occupational exposure and asthma
  • Environmental Toxicology and Ecotoxicology
  • Animal Nutrition and Physiology
  • Food Safety and Hygiene
  • Dye analysis and toxicity
  • Potato Plant Research
  • Trace Elements in Health
  • Aluminum toxicity and tolerance in plants and animals
  • Heavy Metals in Plants
  • Salmonella and Campylobacter epidemiology
  • Air Quality and Health Impacts

Agence Nationale de Sécurité Sanitaire de l’Alimentation, de l’Environnement et du Travail
2014-2025

Laboratoire de Biotechnologie et Chimie Marines
2024

Agence Nationale des Fréquences
2005-2022

Food and Agriculture Organization of the United Nations
2017-2019

Advanced Network and Services (United States)
2013

Université Claude Bernard Lyon 1
2000-2006

Centre Hospitalier Universitaire d'Angers
2006

Institut National de la Recherche Agronomique
2005-2006

Ministère de l'Agriculture
2005

AgroParisTech
2004

This report represents the conclusions of a Joint FAO/WHO Expert Committee convened to evaluate safety various food additives, including flavouring agents, with view recommending acceptable daily intakes (ADIs) and preparing specifications for identity purity. The also evaluated risk posed by two contaminants, aim advising on management options purpose public health protection. first part contains general discussion principles governing toxicological evaluation assessment intake additives...

10.4103/ijmr.ijmr_85_17 article EN The Indian Journal of Medical Research 2018-08-01

The EFSA ANS Panel was asked to provide a scientific opinion on the safety of green tea catechins from dietary sources including preparations such as food supplements and infusions.Green is produced leaves Camellia sinensis (L.) Kuntze, without fermentation, which prevents oxidation polyphenolic components.Most polyphenols in are catechins.The considered possible association between consumption (-)-epigallocatechin-3-gallate (EGCG), most relevant catechin tea, hepatotoxicity.This based...

10.2903/j.efsa.2018.5239 article EN cc-by-nd EFSA Journal 2018-04-01

The EFSA Panel on Food Additives and Nutrient Sources added to (ANS) provides a scientific opinion re-evaluating the safety of silicon dioxide (E 551) when used as food additive. forms synthetic amorphous silica (SAS) E 551 include fumed hydrated (precipitated silica, gel hydrous silica). Scientific Committee (SCF) established group acceptable daily intake (ADI) 'not specified' for silicates. SAS materials in available biological toxicological studies were different their physicochemical...

10.2903/j.efsa.2018.5088 article EN cc-by-nd EFSA Journal 2018-01-01

To estimate the dietary exposure of main minerals and trace elements from retail food typically consumed by French population, samples were purchased then prepared cooked prior to analysis. A total 1080 individual composites collected analysed for 18 (arsenic, lead, cadmium, aluminium, mercury, antimony, chrome, calcium, manganese, magnesium, nickel, copper, zinc, lithium, sodium, molybdenum, cobalt selenium). Intakes calculated different consumption patterns found in France average high...

10.1080/02652030500135367 article EN Food Additives & Contaminants 2005-07-01

This study reports estimates on dietary exposure from the first French Total Diet Study (FTDS) and compares these with both existing tolerable daily intakes for toxins calculated during previous studies. To estimate of population to principal mycotoxins in diet (as consumed), 456 composite samples were prepared 2280 individual analysed aflatoxins, ochratoxin A, trichothecenes, zearalenone, fumonisins patulin. Average high percentile taking account different eating patterns adults, children...

10.1080/02652030500159938 article EN Food Additives & Contaminants 2005-07-01

The present opinion deals with the re-evaluation of safety food-grade carrageenan (E 407) and processes Eucheuma seaweed 407a) used as food additives. Because structural similarities, Panel concluded that processed can be included in evaluation carrageenan. Poligeenan (average molecular weight 10-20 kDa) has not been authorised a additive is any applications. In its 407a), noted ADME database was sufficient to conclude absorbed intact; subchronic toxicity study performed almost complying EU...

10.2903/j.efsa.2018.5238 article EN cc-by-nd EFSA Journal 2018-04-01

In the frame of second French Total Diet Study (TDS), 15+1 EU priority polycyclic aromatics hydrocarbons (PAHs) were analyzed in 725 foodstuffs habitually consumed by population, using gas chromatography coupled to tandem mass spectrometry, after pressurized liquid extraction and purification on PS-DVB stationary phase. The highest PAH concentrations recovered corresponded following contributors: chrysene (25.7%), benzo[b]fluoranthene (15.0%) benz[a]anthracene (9.0%) whereas lowest those...

10.1016/j.envint.2012.12.011 article EN cc-by-nc-nd Environment International 2013-01-31

The Panel on Food Additives and Nutrient Sources added to (ANS) provided a scientific opinion re-evaluating the safety of sodium nitrate (E 251) potassium 252) when used as food additives. current acceptable daily intakes (ADIs) for 3.7 mg/kg body weight (bw) per day were established by SCF (1997) JECFA (2002). available data did not indicate genotoxic potential nitrate. carcinogenicity studies in mice rats negative. considered derivation an ADI based formation methaemoglobin, following...

10.2903/j.efsa.2017.4787 article EN cc-by-nd EFSA Journal 2017-06-01

A total diet study (TDS) was undertaken to estimate the chronic dietary exposure pesticide residues and health risks for French infants young children below 3 years old. As a whole, 516 pesticides metabolites were analysed in 309 food composite samples including 219 manufactured baby foods 90 common foods, which cover 97% of children's diet. These prepared using 5,484 products purchased during all seasons from 2011 2012 processed as consumed. Pesticide detected 67% quantified 27% 60% foods....

10.1016/j.envint.2020.105529 article EN cc-by Environment International 2020-02-08

The present scientific opinion deals with the evaluation of safety nisin (E 234) in light new toxicological data and proposed extension use unripened cheese heat-treated meat products. Nisin is currently an authorised food additive EU under Annex II Regulation (EC) 1333/2008 for several categories. as a has been evaluated 2006 by EFSA Panel on Food Additives, Flavourings, Processing Aids Materials Contact Food, where acceptable daily intake (ADI) 0.13 mg/kg body weight (bw) was confirmed...

10.2903/j.efsa.2017.5063 article EN cc-by-nd EFSA Journal 2017-12-01

An estimation of the dietary exposure French consumers to 21 essential and non-essential mineral elements using duplicate meals (breakfast lunch) purchased from catering establishments was investigated after digestion by a closed vessel microwave procedure quantification ICP-MS. Daily estimates for metals minerals were compared with Provisional Tolerable Weekly Intakes (PTWI), Intake (TDI) or Acceptable (ADI), as established FAO/WHO estimate risk toxicity, US Recommended Allowances (US RDA)...

10.1080/0265203021000031573 article EN Food Additives & Contaminants 2003-01-01

The effects of exercise training and food restriction on the regulation lipolysis were studied comparatively in adipocytes isolated from male female rats. Exercise inhibited cell proliferation parametrial, but not epididymal adipose tissue, whereas it significantly reduced adipocyte size both fat depots. Adipocyte capacity for responding lipolytically to epinephrine (10 microns) or ACTH (1 micron) was markedly increased by training. Enhanced also observed when cells exercise-trained animals...

10.1152/ajpendo.1980.239.6.e422 article EN AJP Endocrinology and Metabolism 1980-12-01

As first described in the 1980s, core food intake model allows a precise assessment of dietary nutrient and exposure to contaminants insofar as it reflects eating habits target population covers most important foods terms consumption, selected contaminant contribution. This has been used set up sampling strategy second French Total Diet Study (TDS) with aim obtaining realistic panorama intakes for whole population, useful quantitative risk assessment. Data on consumption trends from...

10.1080/02652030802695506 article EN Food Additives & Contaminants Part A 2009-05-01
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