A5078901092- Antibiotic Resistance in Bacteria
- Vibrio bacteria research studies
- Bacterial biofilms and quorum sensing
- Infections and bacterial resistance
- Pharmaceutical and Antibiotic Environmental Impacts
- Hepatitis B Virus Studies
- Plant Pathogenic Bacteria Studies
- Antibiotic Use and Resistance
- Enterobacteriaceae and Cronobacter Research
- Antibiotics Pharmacokinetics and Efficacy
- Hepatitis C virus research
- Salmonella and Campylobacter epidemiology
- Probiotics and Fermented Foods
- Pneumonia and Respiratory Infections
- Hepatitis Viruses Studies and Epidemiology
- Cystic Fibrosis Research Advances
- Antimicrobial Resistance in Staphylococcus
- Tracheal and airway disorders
- Molecular Biology Techniques and Applications
- Escherichia coli research studies
- Suicide and Self-Harm Studies
- Bacterial Identification and Susceptibility Testing
- Risk Perception and Management
- Advancements in Transdermal Drug Delivery
- Restraint-Related Deaths
Universidad Internacional De La Rioja
2024-2025
University of the Basque Country
2013-2024
Hospital Clínico San Carlos
2011-2023
Spanish National Cancer Research Centre
2022
Institute of Medical Ethics
2021
Centro de Investigación Biomédica en Red de Salud Mental
2011-2012
Instituto de Investigación Sanitaria del Hospital Clínico San Carlos
2012
Carbapenem resistant Acinetobacter baumannii is a major global concern, especially in countries of the Middle East and North Africa, where antibiotic resistance rates are on rise. The aim this study was to genomic characteristics antimicrobial susceptibility profile thirty-six multidrug A. clinical isolates obtained hospitals from Alexandria, Egypt. Antibiotic were estimated by determination Minimum Inhibitory Concentrations. Carbapenemase genes, other genes virulence factors then screened...
Eighty-two carbapenem-resistant isolates of Acinetobacter baumannii from a single hospital in Bilbao were typed into two major clusters and several subclusters. Disk synergy tests PCR indicated the production zinc-independent OXA-class carbapenemase. Sequencing identified this enzyme, OXA-40, as variant OXA-24-OXA-25-OXA-26 cluster.
Objective: The main objectives of this study were to assess the clonal relatedness Acinetobacter baumannii carbapenem-resistant isolates recovered from Iberian Peninsula and investigate production carbapenemases.
A collection of 70 clinical isolates Acinetobacter baumannii from Bilbao in northern Spain was examined by PCR for the presence class 1 integron structures. The organisms comprised 21 distinct RAPD genotypes, with 10 antibiogram patterns. Four different structures were detected a total 59 (84%) isolates, two predominant found 20 and 30 each. No clear differences could be correlated or absence structures, but sequence analysis internal regions indicated homology genes encoding ANT(2″)...
In this study we describe the clinical and molecular characteristics of an outbreak due to carbapenem-resistant Klebsiella pneumoniae (CR-KP) producing CTX-M-15 OXA-48 carbapenemase. Isogenic strains, carbapenem-susceptible K. (CS-KP) CTX-M-15, were also involved in outbreak. From October 2010 December 2012 a total 62 CR-KP 23 CS-KP isolated from samples 42 patients (22 had resistant isolates, 14 susceptible 6 both CR CS isolates). All underlying diseases 17 them (14 with 3 CS-KP) received...
Using a combination of short- and long-read DNA sequencing, we have investigated the location antibiotic resistance genes characterized mobile genetic elements (MGEs) in three clinical multi-drug resistant Acinetobacter baumannii. The isolates, collected Bolivia, clustered separately with different international clonal lineages. We found diverse array transposons, plasmids islands related to insertion sequence (IS) elements, which were located both chromosome plasmids, conferred multiple...
Abstract Suicide remains a frequent cause of death in adults, often overlooked despite known risk factors like mental disorders, older age, and chronic illness. Emergency department visits offer critical opportunities to identify suicidal ideation provide preventive care. This study reviewed deaths within 30 days discharge from the emergency major public hospital Alicante, Spain, focusing on by suicide. Over five years, 529,312 were recorded, with 453,599 patients (85.7%) discharged home. Of...
The objective of this study was the phenotypic and genotypic characterization a carbapenem resistant Acinetobacter baumannii (CRAB) isolate. isolate, recovered in Northern Spain 2019, identified by MALDI-TOF to species level. Antimicrobial susceptibility testing performed using Phoenix BD NMIC-502 Panel, E-test, broth microdilution methods. presence metallo-β-lactamase (MBL) verified PCR immunochromatographic assays. genetic location MBL confirmed S1-PFGE followed Southern blot...
Infections caused by carbapenem-resistant Acinetobacter baumannii are a global threat causing high number of fatal infections. This microorganism can also easily acquire antibiotic resistance determinants, making the treatment infections big challenge, and has ability to persist in hospital environment under wide range conditions. The objective this work was study molecular epidemiology genetic characteristics two blaOXA24/40Acinetobacter outbreaks (2009 2020-21) at tertiary Northern Spain....
Acinetobacter baumannii is an emerging multidrug-resistant pathogen and very little information available regarding its imipenem resistance in Latin American countries such as Bolivia. This study investigated the antimicrobial profile of 46 clinical strains from different hospitals Cochabamba, Bolivia, March 2008 to July 2009, presence carbapenemases a mechanism imipenem. Isolates were obtained patients (one isolate per patient; 30 males,16 females) with age range 1 day 84 years, collected...
Acinetobacter baumannii causes serious hospital-acquired infections and has been positioned as a priority organism by the World Health Organization. This study includes 36 A. isolates from children hospital recovered between March 2014 May 2015 in Cochabamba. The majority of were blood cultures (n = 10, 31.3%) respiratory samples 11, 34.4%); 53% patients younger than 1 month old. Most these 30, 80.6%) extremely drug resistant 8.3% multidrug resistant. circulation 2 predominant clones...
Acinetobacter baumannii is opportunistic in debilitated hospitalised patients. Because information from some South American countries was previously lacking, this study examined the emergence of multi-resistant A. three hospitals Cochabamba, Bolivia, 2008 to 2009.Multiplex PCR used identify main resistance genes 15 isolates. RT-PCR measure gene expression. The genetic environment these also analysed by amplification and sequencing. Minimum inhibitory concentrations were determined for key...
Acinetobacter seifertii is a recently described species that belongs to the calcoaceticus-Acinetobacter baumannii complex. It has been recovered from clinical samples and sometimes associated with antimicrobial resistance determinants. We present here case of three A. isolates which were initially identified as sp. by phenotypic methods but no identification at level was achieved using semi-automated methods. The further analysed whole genome sequencing seifertii. Due fact isolated serious...
The increasing rates of antimicrobial resistance among carbapenem-resistant Acinetobacter baumannii in the Middle East and North Africa are one major concerns for healthcare settings. We characterised first A. isolate harbouring five β-lactamases identified Egypt. Ale25 was obtained from an ICU patient a hospital Alexandria. phenotypically genotypically screened carbapenemase genes. resistant to carbapenems, aminoglycosides, fluoroquinolones cefiderocol. Whole-Genome Sequencing β-lactamase...
ABSTRACT PCR fingerprinting was used for the epidemiological investigation of 64 Pseudomonas aeruginosa isolates collected from 16 chronic bronchiectasis patients without cystic fibrosis: 56% harbored one clone, 12.5% carried a single major type with minor variants, and 31.5% two clones. Only minority acquisitions antibiotic resistance related to acquisition exogenous strains. Mucoid nonmucoid sets did not display any consistent differences in their patterns. The genetic similarity among...