Daniela Magalhães Nolasco

ORCID: 0000-0003-2901-3107
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About
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Research Areas
  • Cystic Fibrosis Research Advances
  • Neonatal Respiratory Health Research
  • Metabolism and Genetic Disorders
  • Infant Development and Preterm Care
  • Neonatal Health and Biochemistry
  • Advanced biosensing and bioanalysis techniques
  • Plant Pathogens and Fungal Diseases
  • Metabolomics and Mass Spectrometry Studies
  • Chemical Safety and Risk Management
  • Antifungal resistance and susceptibility
  • Microfluidic and Bio-sensing Technologies
  • Biotin and Related Studies
  • Carcinogens and Genotoxicity Assessment
  • Folate and B Vitamins Research
  • Photovoltaic Systems and Sustainability
  • Pesticide Residue Analysis and Safety
  • Click Chemistry and Applications
  • Antibiotics Pharmacokinetics and Efficacy
  • Fungal Infections and Studies
  • Pesticide Exposure and Toxicity

Universidade Federal de Minas Gerais
2019-2023

Newborn Screening Ontario
2023

Escuela Colombiana de Carreras Industriales
2020

Universidade Federal de Alfenas
2007

Sporotrichosis is a sporadic and rare mycotic infection in most of the developed world. In many parts developing world, sporotrichosis much more commonly recognized, but epidemiological data are generally lacking from these regions. We report epidemiological, clinical, treatment 238 cases culture-proven occurring relatively remote area south central highlands Peru that were retrospectively collected during 1995–1997. Most (60%) occurred children aged ≤14 years, affected anatomic site was...

10.1086/313607 article EN Clinical Infectious Diseases 2000-01-01

Objective To assess the accuracy of sweat conductivity among newborns and very young infants. Design Prospective, population-based, diagnostic test study. Setting Public Statewide Newborn Screening Programme where incidence rate cystic fibrosis (CF) is ≈1:11 000. Patients Newborns infants with positive two-tiered immunoreactive trypsinogen. Interventions Sweat chloride were performed simultaneously, on same day facility by independent technicians, cut-off values 80 mmol/L 60 mmol/L,...

10.1136/archdischild-2022-324723 article EN Archives of Disease in Childhood 2023-03-13

Pesticides constitute a category of chemical products intended specifically for the control and mitigation pests. With their constant increase in use, risk to human health environment has increased proportionally due occupational environmental exposure these compounds. The use chemicals is associated with several toxic effects related acute chronic toxicity, such as infertility, hormonal disorders cancer. present work aimed study metabolic profile individuals occupationally exposed...

10.3390/metabo13050596 article EN cc-by Metabolites 2023-04-27

Objective The prevalence of biotinidase deficiency and the frequency gene variants in Brazil are not documented. We aimed to determine incidence partial profound state Minas Gerais, Brazil, calculate newborn screening program Gerais. Methods Neonates (1,168,385) were screened from May 2013 June 2018. Those detected with abnormal activity based on semi-quantitative assays underwent confirmatory serum tests. was sequenced all confirmed cases. Results combined estimated at 1:13,909 live births...

10.1177/0969141319892298 article EN Journal of Medical Screening 2019-12-04

The aim of the present study was to determine 2,5-hexanedione (2,5-HD), a metabolite n-hexane, by gas chromatography/flame ionization detection in 31 workers exposed n-hexane after two types sample pretreatment, i.e., with (total 2,5-HD) and without (free acid hydrolysis. mean urinary 2,5-HD 0.52 mg/L (free) 2.88 (total), this difference being significant (Student t-test, p < 0.05). differences results according treatment support need modify current Brazilian legislation, which proposes...

10.1590/s0100-40422007000400009 article EN cc-by-nc Química Nova 2007-08-01

Abstract Quantitative analysis of amino acids in blood and urine is primarily indicated for the diagnosis acid disorders. The high‐performance liquid chromatography (HPLC) technique frequently used this detection. frequency sample collection on filter paper has been increasing exponentially, there are many advantages attributed to processing biological samples way. aim study was validate a quantitative by HPLC collected establish reference values neonatal period. Dried dried respectively 58...

10.1002/bmc.4931 article EN Biomedical Chromatography 2020-06-26

En este documento, se desarrolla un modelo de sombreado para sistemasde generación solar fotovoltaica emplazados en dos entornos, uno rural, ubicadoen la sabana cundiboyacense y otro dentro del con-urbano capital colombiana.Ambos sistemas consideran una carga eléctrica típica hogar promedio. A partirde esta estimación dimensionan los componentes sistema fotovoltaico.En ocasión no bancos baterías. El sobrelos paneles realiza por medio SAM, insertando objetos altura considerable enambos...

10.18180/tecciencia.2021.30.2 article ES TECCIENCIA 2020-02-02

To the Editor, Sweat conductivity (SC) is a well-established screening test for Cystic Fibrosis (CF).1,2 It semi-automated, fast, doesn’t require skilled technicians or specialized personnel, and needs small amount of sweat. Moreover, one response to demanding labour-intensive requirement robust quality sweat testing has been samples by electrical conductivity.3As every laboratory method, SC subject error. Then, it should be assessed tested ensure that produces results which make reliable...

10.22541/au.159586031.15037961 preprint EN Authorea (Authorea) 2020-07-27

Background: Sweat conductivity (SC) is a semi-automated method widely used as screening test for Cystic Fibrosis. Quantity not sufficient (QNS) defined when collecting volume lower than 15 μl of sweat during 30 minutes. Objective: To verify the rate and factors related to QNS SC in newborns young infants. Methods: Newborns infants aged less three months that had undergone after two abnormal immunoreactive trypsinogen results, were recruited prospectively consecutively. Statistical analysis...

10.22541/au.161404670.03019523/v1 preprint EN Authorea (Authorea) 2021-02-23
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