Muhammad Jawad Nasim

ORCID: 0000-0003-2911-2607
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Research Areas
  • Selenium in Biological Systems
  • Rice Cultivation and Yield Improvement
  • Organoselenium and organotellurium chemistry
  • Sulfur Compounds in Biology
  • Agricultural Systems and Practices
  • Free Radicals and Antioxidants
  • Ethnobotanical and Medicinal Plants Studies
  • Genomics, phytochemicals, and oxidative stress
  • Agricultural Economics and Practices
  • Plant Stress Responses and Tolerance
  • Nanoparticles: synthesis and applications
  • Moringa oleifera research and applications
  • Plant responses to water stress
  • Agricultural Science and Fertilization
  • Garlic and Onion Studies
  • Plant Micronutrient Interactions and Effects
  • Essential Oils and Antimicrobial Activity
  • Plant nutrient uptake and metabolism
  • Crop Yield and Soil Fertility
  • African Botany and Ecology Studies
  • Cardiac Imaging and Diagnostics
  • Redox biology and oxidative stress
  • 2D Materials and Applications
  • Medical and Biological Ozone Research
  • Seed and Plant Biochemistry

Saarland University
2016-2025

Basingstoke and North Hampshire Hospital
2025

GIFT University
2025

Institute of Business Management
2025

Sejong University
2024

King Fahd Military Medical Complex
2023

Ayub Agriculture Research Institute
2023

Government of Punjab
2021-2022

Government of Pakistan
2021-2022

Bangladesh Rice Research Institute
2017-2022

Agricultural land use and distribution of cultivated crops expressed in cropping pattern (CP) constitute the base for increasing produtivity. An in-depth study was conducted on existing CPs Bangladesh each every upazila (sub-districts) using semi structured questionnaire data validation by stakeholder consultation workshop 64 districts. Three hundred sixteen were identified throughout excluding very minor ones. Topmost five only rice containing CPs, which covered 51% net cropped area. The...

10.3329/brj.v21i2.38195 article EN Bangladesh Rice Journal 2018-09-14

Alzheimer's disease (AD) has a complex and not-fully-understood etiology. Recently, the serotonin receptor 5-HT6 emerged as promising target for AD treatment; thus, here new series of 5-HT6R ligands with 1,3,5-triazine core selenoether linkers was explored. Among them, 2-naphthyl derivatives exhibited strong affinity selectivity over 5-HT1AR (13–15), 5-HT7R (14 15), 5-HT2AR (13). Compound 15 displayed high other central nervous system receptors low risk cardio-, hepato-, nephrotoxicity no...

10.1021/acs.jmedchem.3c02148 article EN cc-by Journal of Medicinal Chemistry 2024-01-08

Multidrug resistance of cancer cells to cytotoxic drugs still remains a major obstacle the success chemotherapy in treatment. The development new drug candidates which may serve as P-glycoprotein (P-gp) efflux pump inhibitors is promising strategy. Selenium analogues natural products, such flavonoids, offer an interesting motif from perspective design. Herein, we report biological evaluation novel hybrid compounds, bearing both flavone core (compounds 1–3) or bioisosteric analogue 4–6) and...

10.3390/ph13120453 article EN cc-by Pharmaceuticals 2020-12-11

Bioconversion of organic waste requires the development and application rather simple, yet robust technologies capable transferring biomass into energy sustainable materials for future. Food plays a significant role in this process as its valorisation reduces at same time avoids additional exploitation primary resources. Nonetheless, to literally become “litterate”. extensive research such large-scale methods is required. Here, we highlight some promising avenues which fulfill these “waste...

10.3389/fnut.2024.1325190 article EN cc-by Frontiers in Nutrition 2024-05-06

Plant extracts serve as reducing and coating agents are, therefore, commonly employed for the generation of silver (Ag) nanoparticles (NPs). extract mediated synthesis Ag NPs is a green, environmentally friendly cost-effective technique which offers new potential alternative to chemically synthesized NPs, decreasing utilization hazardous toxic chemicals protecting environment. Origanum vulgare L. were evaluated total flavonoid phenol content. The free radical scavenging activity was...

10.1186/s13568-020-01100-9 article EN cc-by AMB Express 2020-09-05

Silver nanoparticles (Ag NPs) represent one of the most widely employed metal-based engineered nanomaterials with a broad range applications in different areas science. Plant extracts (PEs) serve as green reducing and coating agents can be exploited for generation Ag NPs. In this study, phytochemical composition ethanolic extract black currant (Ribes nigrum) leaves was determined. The main components include quercetin rutinoside, hexoside, glucuronide, malonylglucoside quercitrin....

10.3390/antibiotics11101415 article EN cc-by Antibiotics 2022-10-14

Trigonella hamosa (Genus: Trigonella; Family: Fabaceae), also known as branched Fenugreek, is a medicinally important plant traditionally employed for the treatment of common ailments. This study aimed at evaluation chemical composition and biological profile T. hamosa. The hydro-methanolic extract (METH) was prepared through maceration, subjected to solvent–solvent fractionation obtain n-hexane fraction (HFTH), chloroform (CFTH) n-butanol (BFTH). Chemical profiling carried out preliminary...

10.1016/j.arabjc.2023.104795 article EN cc-by-nc-nd Arabian Journal of Chemistry 2023-03-16

The last decade has witnessed a renewed interest in antimicrobial agents. Plants have received particular attention and frequently rely on the spontaneous enzymatic conversion of an inactive precursor to active agent. Such two-component substrate/enzyme defence systems can be reconstituted ex vivo. Here, alliin/alliinase system from garlic seems rather effective against Saccharomyces cerevisiae, whilst glucosinolate/myrosinase mustard appears more certain bacteria. Studies with myrosinase...

10.1177/1934578x1501001025 article EN Natural Product Communications 2015-10-01

In view of the pressing need to identify new antibacterial agents able combat multidrug-resistant bacteria, we investigated a series fused selenazolinium derivatives (1-8) regarding their in vitro antimicrobial activities against 25 ESKAPE-pathogen strains. Ebselen was used as reference compound. Most selenocompounds demonstrated an excellent activity all S. aureus strains, with comparable or even exceeding one ebselen. contrast ebselen, some (1, 3, and 7) displayed significant actions...

10.3390/molecules22122174 article EN cc-by Molecules 2017-12-08

Untreated wastewater used for irrigating crops is the major source of toxic heavy metals and other pollutants in soils. These affect plant growth deteriorate quality edible parts growing plants. Phytohormone (IAA) exopolysaccharides (EPS) producing growth-promoting rhizobacteria can reduce toxicity by stabilizing them soil. The present experiment was conducted to evaluate IAA EPS-producing rhizobacterial strains improving growth, physiology, antioxidant activity Brassica juncea (L.) under...

10.3390/app11094160 article EN cc-by Applied Sciences 2021-05-02

Brewer's spent grains (BSG) are a by-product of the beer-brewing industry, often employed as animal feeding stuffs. With BSG being rich not only in proteins, lipids, and dietary fiber but also certain phytochemicals, it constitutes potentially valuable food source that could be functional food, e.g. against chronic inflammatory diseases. Several types bread were prepared with various amounts flour replacement (0, 10, 20, 40, 60, 80 100%), either employing wet or dried after pressing. Total...

10.1039/d1fo03090f article EN Food & Function 2022-01-01

The rapid advancement of artificial intelligent and information technology has led to a critical need for extremely low power consumption excellent efficiency. capacity neuromorphic computing handle large amounts data with garnered lot interest during the last few decades. For applications, 2D layered semiconductor materials have shown pivotal role due their distinctive properties. This comprehensive review provides an extensive study recent advancements in materials‐based devices especially...

10.1002/sstr.202400386 article EN cc-by Small Structures 2024-10-08

Redox-modulating compounds derived from natural sources, such as redox active secondary metabolites, are currently of considerable interest in the field chemoprevention, drug and phytoprotectant development. Unfortunately, exact occasionally even selective activity products, underlying (bio-)chemical causes thereof, often only poorly understood. A combination nematode- yeast-based assays provides a powerful platform to investigate possible biological new compound also explore “redox link”...

10.3390/molecules190812258 article EN cc-by Molecules 2014-08-13

Allicin (diallylthiosulfinate) is the principal organosulfur compound present in freshly damaged garlic tissue which exhibits a wide range of biological actions including antibacterial, antifungal, antiviral and anticancer properties. The antifungal activities allicin were investigated against plant pathogenic fungi agriculture importance. Furthermore, yeast genome haploinsufficiency screening was also employed to decipher mode action allicin. Wildtype 1152 mutant strains (each deprived one...

10.3390/app10072563 article EN cc-by Applied Sciences 2020-04-08
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