A5100354521- Liver Disease Diagnosis and Treatment
- Nutritional Studies and Diet
- Esophageal Cancer Research and Treatment
- Cancer, Lipids, and Metabolism
- Hepatitis B Virus Studies
- Obstructive Sleep Apnea Research
- Neuroscience of respiration and sleep
- Obesity, Physical Activity, Diet
- Aquaculture Nutrition and Growth
- Hepatitis C virus research
- Esophageal and GI Pathology
- Inflammatory Myopathies and Dermatomyositis
- Biochemical effects in animals
- Physical Activity and Health
- Ferroptosis and cancer prognosis
- Asthma and respiratory diseases
- Bone Tissue Engineering Materials
- Cardiovascular and Diving-Related Complications
- Gastric Cancer Management and Outcomes
- COVID-19 Clinical Research Studies
- Acupuncture Treatment Research Studies
- Diet and metabolism studies
- Systemic Lupus Erythematosus Research
- Radiomics and Machine Learning in Medical Imaging
- Blood Pressure and Hypertension Studies
University of Science and Technology of China
2023-2025
Guangdong Pharmaceutical University
2022-2025
Guangxi University of Chinese Medicine
2009-2025
Guangxi University
2013-2025
Shanxi University
2025
The Affiliated Yongchuan Hospital of Chongqing Medical University
2023-2025
Chongqing Medical University
2023-2025
Changchun University
2024-2025
Wannan Medical College
2024-2025
Peking University Shenzhen Hospital
2025
Diisononyl phthalate (DINP) has been widely used in polyvinyl chloride (PVC) products and is ubiquitous as a substitute; however, its toxicity due to exposure remains be determined. This study investigated the oxidative damage induced by DINP production of pro-inflammation cytokines interleukin-1 (IL-1) tumour necrosis factor-α (TNF-α). Oral inflammatory responses liver kidney tissues through accumulation ROS, which may an underlying mechanism for toxicity. These changes contribute hepatic...
Aims To evaluate the effects of habitual leisure-time physical activity (LTPA) on incident type 2 diabetes in a prospective cohort Chinese adults with impaired fasting glucose (IFG). Methods 44 828 aged 20–80 years newly detected IFG but free from cardiovascular and cerebrovascular disease were recruited followed up 1996 to 2014. Incident was identified by plasma ≥7 mmol/L. The participants classified into four categories based their self-reported weekly LTPA: inactive, low, moderate, or...
Abstract Background Data are limited on whether several easily measured indices independent predictors of type 2 diabetes mellitus (T2DM) in hypertensive patients. This study aimed to assess the association hypertriglyceridemic-waist phenotype, triglyceride glucose (TyG) index, lipid accumulation product (LAP), and visceral adiposity index (VAI) with T2DM risk Methods cross-sectional included 5321 patients from baseline survey Guangzhou Heart Study. Face-to-face questionnaire survey,...
Abstract Background Obesity is a crucial risk factor for obstructive sleep apnea (OSA), but the association between adiposity deposition and OSA has not reached consistent conclusion. This study sought to reveal of multiple indicators with risk. Methods cross-sectional included 9,733 participants aged 35–74 years, recruited from an ongoing population-based cohort. was assessed by Berlin Questionnaire. Six indicators, including neck circumference (NC), body fat percentage (BF%), waist-to-hip...
Etiology of esophageal cancer has not yet been clearly documented, especially in high-risk regions. To evaluate the association between salted meat intake and squamous-cell carcinoma (ESCC) to explore its joint effects with alcohol drinking smoking, a population-based case-control study was conducted high ESCC risk area China, including 942 incident cases age- sex-matching controls. A validated food frequency questionnaire used collect information on dietary factors, tobacco smoking....
To investigate current status of diagnosis and treatment bladder cancer in China.A database was generated by Chinese Bladder Cancer Consortium (CBCC). From January 2007 to December 2012, 14,260 cases from 44 CBCC centers were included. Data diagnosis, pathology collected.The average age 63.5 year-old most patients male (84.3%). The common histologic types urothelial carcinoma (91.4%), adenocarcinoma (1.8%), squamous (1.9%). According 1973 2004 WHO grading system, 42.0%, 41.0%, 17.0% grade 1,...
Abstract Background No studies investigated the whole effect of modifiable lifestyle factors on OSA risk. This study aimed to examine individual and combined effects risk among Chinese adults. Methods cross-sectional included 9733 participants aged 35 74 years from baseline survey Guangzhou Heart Study. was evaluated by Berlin Questionnaire. The healthy score (HLS), representing overall lifestyles, derived seven factors: active smoking, passive alcohol, diet, waist-hip ratio, leisure-time...
Mounting evidence has revealed that the interactions and dynamic alterations among immune cells are critical in shaping tumor microenvironment ultimately map onto heterogeneous clinical outcomes. Currently, underlying significance of cell evolutions remains largely unexplored hepatocellular carcinoma (HCC). A total 3,817 1,750 HCC patients 15 independent public datasets were retrieved. The Seurat Monocle algorithms used to depict T evolution, nonnegative matrix factorization (NMF) was...
Background Cadmium (Cd) is classified as a human carcinogen probably associated with epigenetic changes. DNA methylation one of mechanisms by which cells control gene expression. Therefore, the present study genome-widely screened methylation-altered genes in liver rats previously exposed to low-dose Cd. Methodology Principal Findings Rats were Cd at 20 nmol/kg every other day for 4 weeks and was analyzed 48th week methylated immunoprecipitation-CpG island microarray. Among 1629 altered...
AIM:To establish a simple model consisting of the routine laboratory variables to predict both minimal fibrosis and cirrhosis in chronic hepatitis B virus (HBV)-infected patients. METHODS:We retrospectively investigated 114 HBV-infected patients who underwent liver biopsy two different hospitals.Thirteen parameters were analyzed by step-wise regression analysis correlation analysis.A new index [globulin/platelet (GP) model] was developed, including globulin (GLOB) platelet count (PLT).GP =...
Asthma is a complex pulmonary inflammatory disease characterized by the hyper-responsiveness, remodeling and inflammation of airways. Formaldehyde common indoor air pollutant that can cause asthma in people experiencing long-term exposure. The irritant effect adjuvant are two possible pathways formaldehyde promoted asthma.To explore neural mechanisms formaldehyde, 48 Balb/c mice six experimental groups were exposed to (a) vehicle control; (b) ovalbumin; (c) (3.0 mg/m(3)); (d)...
Objective This study was conducted to assess the reproducibility and validity of a food frequency questionnaire (FFQ) that developed overall dietary consumption via pattern method in rural population southwest China. Methods A total 179 participants aged between 40 70 years old were included this study. Participants administered FFQ at baseline (FFQ1) one year later (FFQ2) reproducibility. Six 3-day 24-hour recalls (24HRs) completed administrations two FFQs determine validity. Dietary...
Chronic lymphocytic thyroiditis (CLT) is a common autoimmune disorder. The possible pathogenic role and mechanism of dibutyl phthalate (DBP) in CLT still controversial. Experiments were conducted after 35-days oral exposure to the three concentrations DBP or saline, immunizations with thyroglobulin (TG). Healthy female Wistar rats randomly divided into ten groups (n = 8 each): (A) saline control, (B) 0.5 mg/kg/d DBP, (C) 5 (D) 50 (E) TG-immunized group, (F) TG- combined (G) (H) (I) plus 100...
Objective Despite the known benefits of physical activity, effect habitual activity (HPA) on depression and anxiety remains unclear. This study aimed to investigate association HPA with risk among Chinese adults, consideration disease severity. Methods The participants in this multicentre cross-sectional were from nationwide survey psychology behaviour residents. Depression measured using nine-item Patient Health Questionnaire seven-item Generalised Anxiety Disorder scale. was assessed by...
This study is to evaluate the efficacy of participatory ergonomic (PE) intervention on musculoskeletal disorders (MSDs) and work ability among young dental professionals in China.A cluster randomized controlled trail was conducted during 2015-2016. Twenty-nine departments from five hospitals South China were into (14 departments) control (15 departments), with individuals 125 138 professionals, respectively. Main interventions involved posture, repetitive motions, tool usage, break...
<sec> <title>BACKGROUND</title> Patients with chronic non-communicable diseases require long-term adherence to medication, but this can carry a high risk of adverse drug events (ADEs). ADE monitoring relies mainly on passive methods, so we tested the viability using an interactive voice response system (IVRS). </sec> <title>OBJECTIVE</title> Investigate effectiveness IVRS in collecting data from patients hypertension or diabetes mellitus (DM). <title>METHODS</title> Eligible DM were...
Despite surgical and intravesical chemotherapy interventions, non-muscle invasive bladder cancer (NMIBC) poses a high risk of recurrence, which significantly impacts patient survival. Traditional clinical characteristics alone are inadequate for accurately assessing the NMIBC necessitating development novel predictive tools. We analyzed microarray data samples obtained from ArrayExpress GEO databases. LASSO regression was utilized to develop signature. combined gene signature...