A5020514095- Cardiac, Anesthesia and Surgical Outcomes
- Mechanical Circulatory Support Devices
- Intensive Care Unit Cognitive Disorders
- Cardiac and Coronary Surgery Techniques
- Cardiac Arrest and Resuscitation
- Surgical Simulation and Training
- Cardiac Structural Anomalies and Repair
- Cardiac Health and Mental Health
- Cardiac Valve Diseases and Treatments
- Simulation-Based Education in Healthcare
- Coronary Interventions and Diagnostics
- Acute Kidney Injury Research
- Soft Robotics and Applications
- COVID-19 and healthcare impacts
- Family and Patient Care in Intensive Care Units
- Micro and Nano Robotics
- Tissue Engineering and Regenerative Medicine
- Venous Thromboembolism Diagnosis and Management
- Anatomy and Medical Technology
- Infective Endocarditis Diagnosis and Management
- Acute Myocardial Infarction Research
- Healthcare cost, quality, practices
- Blood transfusion and management
- Characterization and Applications of Magnetic Nanoparticles
- Innovations in Medical Education
Medisch Spectrum Twente
2015-2025
University of Twente
2017-2025
The Netherlands Cancer Institute
2024
Thorax Foundation
2017-2023
Management Support Technology (United States)
2023
Dutch Institute for Clinical Auditing
2022
Leiden University
2022
Many membrane oxygenator patients suffer from renal disfunction. For these patients, a novel device integrating artificial lung and kidney support is being developed. Although outside-in blood flow standard for oxygenators, this not typical hemodialysis systems. The effect of on the efficiency fibers continuous hemofiltration yet unclear. This study evaluates commercial hemodialyzer membranes utilized compared to traditional inside-out mode regarding clearance urea creatinine,...
Artificial membrane lungs are composed of hollow fiber membranes. Blood flows with low velocities in the bundle, forming a laminar boundary layer near surfaces that limits gas transfer. Passive blood mixing within array is utilized to overcome this limitation. Nevertheless, it unclear which extent and configuration contribute performance oxygenators. This study aims evaluate effect replacement on exchange oxygenators better understanding influence transfer mechanisms blood. Furthermore,...
Intravascular surgical instruments require precise navigation within narrow vessels, necessitating maximum flexibility, minimal diameter, and high degrees of freedom. Existing tools often lack control during insertion due to undesirable bending, limiting vessel accessibility risking tissue damage. Next-generation aim develop hemocompatible untethered devices controlled by external magnetic forces. Achieving this goal remains complex testing implementation challenges in clinical environments....
Extracorporeal membrane oxygenation (ECMO) is a temporary lifesaving treatment for critically ill patients with severe respiratory or cardiac failure. Studies demonstrated the feasibility of in-hospital mobilizing during and after ECMO preventing neuromuscular weakness impaired physical functioning. Despite more compact mobile devices, implementation ambulatory remains labor-intensive, complex, challenging. It requires large multidisciplinary team to carry equipment, monitor physically...
Abstract Aim Delirium is common in patients aged over 70 years after cardiac surgery. Screening to detect delirium high-risk important, yet hypoactive often missed nurse-reported screening. Polymorphic delta waves are associated with delirium, and can be detected single-channel electroencephalography (SC-EEG). The aim of the study assess whether SC-EEG as a screening instrument for will increase detection rate postoperative reduce hospital stay delirious patients. Methods results A...
Introduction Blood transfusion is associated with adverse events and should be prevented. Preoperative identification of patients at risk necessary makes subsequent preventive intervention possible. Many models have been developed which the Transfusion Risk Clinical Knowledge (TRACK) model includes criteria reflecting daily practice. The aim this study to validate update TRACK in a low-transfusion-rate adult cardiac-surgery population. Methods External validation was performed using database...
Preterm birth remains the leading cause of mortality among neonates. Despite improvements in neonatal intensive care over years, current treatments for lung and kidney failure are highly invasive, associated with lifelong disability, limit family integration. Artificial womb artificial placenta technologies offer a promising alternative by providing more tailored less invasive care. Although these share some similarities, differ significantly terms treatment initiation, environment,...
Fourteen Dutch heart centres collected patient-relevant outcomes to support quality improvements in a value-based healthcare initiative that began 2012. This study aimed evaluate the current state of outcome-based improvement within six these centres. Interviews and questionnaires among physicians professionals were combined mixed-methods approach. The analysis indicates predominant focus is on actual monitoring outcomes. A systematic approach for identification potential selection...
Cardiac surgery patients infrequently mobilize during their hospital stay. It is unclear for why mobilization important, and exact progress of activities not available. The aim this study was to select evaluate accelerometers objective qualification in-hospital after cardiac surgery. Six static dynamic patient were defined measure the postoperative Device requirements formulated, available devices reviewed. A triaxial accelerometer (AX3, Axivity) selected a clinical pilot in heart ward...
High-volume extracorporeal membrane oxygenation (ECMO) centers generally have better outcomes than (new) low-volume ECMO centers, most likely achieved by a suitable exposure to cases. To achieve higher level of training, simulation-based training (SBT) offers an additional option for education and extended clinical skills. SBT could also help improve the interdisciplinary team interactions. However, simulators and/or simulations (ECMO sims) techniques may vary in purpose. We present...
Abstract Background Patients infrequently mobilize at the surgical ward after cardiac surgery. Inactivity results in prolonged hospital stay, readmissions and increased cardiovascular mortality. Next, course of in-hospital mobilization activities for patients is unclear. The aim was to evaluate early heart surgery with a poster on Activity Classification Guide Inpatient Activities score from American College Sports Medicine (ACSM). Second, develop Thorax Centrum Twente (TCT) assess...
Patients undergoing surgical aortic valve replacement (SAVR) are at high risk for atrial fibrillation (AF) and stroke after surgery. There is an unmet clinical need to improve prevention in this patient population. The LAA-CLOSURE trial aims assess the efficacy safety of prophylactic closure left appendage cardiovascular death patients bioprosthetic SAVR. This randomized, open-label, prospective multicenter will enroll 1,040 13 European sites. primary endpoint a composite mortality, systemic...
Extracorporeal Membrane Oxygenation (ECMO) is a temporary lifesaving treatment for critically ill patients suffering from severe respiratory and/or cardiac failure. Studies have demonstrated the feasibility of mobilization in ECMO within hospital during their bridge to recovery or transplantation. Ambulatory comprehensive form aimed at preventing neuromuscular weakness and impaired physical functioning after treatment. Despite more compact mobile devices, implementation ambulatory remains...
Abstract The COVID-19 pandemic has had a significant impact on global public health, with long-term consequences that are still largely unknown. This study aimed to assess the data regarding acute cardiovascular hospital admissions in five European centers before and during pandemic. A multicenter, multinational observational registry was created, comparing emergency departments 3-months period 2020 (during pandemic) corresponding 2019 (pre-pandemic). Data patient demographics, test results,...
Heart failure is increasingly prevalent in the elderly. Treatment of patients with heart aims at improving their clinical condition, quality life, prevent hospital (re)admissions and reduce mortality. Unfortunately, only a select group reduced ejection fraction are eligible for Cardiac Resynchronization Therapy where 30–40% remain non-responders need left ventricular support. The aim this study to investigate if shape memory alloy (SMA) able increase mono-chamber static model by 5%. A...
Combining preoperative angiography findings with intraoperative transit time flow measurements (TTFM) may improve patency of coronary artery bypass grafts. Nevertheless, graft might be impaired by native based on the severity stenoses, inferior long-term outcomes. This study investigates impact left anterior descending (LAD) stenosis competitive measured in internal mammary (LIMA) grafts during off-pump grafting.
Pyoderma gangrenosum (PG) is a rare, chronic inflammatory noninfectious dermatosis. It associated with underlying systemic or hematological diseases such as myelodysplastic syndrome (MDS) and can be triggered after surgery. Recognition diagnosis of PG difficult it mimic wound infection. Misdiagnosis could lead to invasive procedures which worsen the disease have possible disastrous aftermath. A 74-year-old male history MDS presents an atypical sternal inflammation. Diagnosis confirmed skin...
Untethered helical magnetic devices (UHMDs) have the potential to navigate bodily fluids using permanent-magnet robotic systems for minimally invasive diagnostic and surgical procedures. These can be actuated by robotically moving rotating permanent magnets (RPMs) achieve controllable steering propulsion simultaneously in a wireless manner. To date, vast majority of motion control UHMDs are constrained operate absence dynamic flow field prior work did not rigorously address fundamental roles...
International coronary revascularization guidelines recommend both, transradial vascular access for angiography/intervention and use of the radial artery as a conduit bypass grafting (CABG). These recommendations may pose clinical dilemma, exposes these arteries to trauma which makes them potentially unsuitable future grafts. In this study, we investigated awareness views cardiologists on guideline recommendations.We performed semi-structured interviews with 50 from 19 centers, who regularly...