A5049486740- Plant Gene Expression Analysis
- Plant biochemistry and biosynthesis
- Plant tissue culture and regeneration
- Plant Molecular Biology Research
- Electrical Contact Performance and Analysis
- Adhesion, Friction, and Surface Interactions
- Chromium effects and bioremediation
- Electronic Packaging and Soldering Technologies
- Biochemical and biochemical processes
- Transgenic Plants and Applications
- Phytochemicals and Antioxidant Activities
- Phytochemicals and Medicinal Plants
- Cancer therapeutics and mechanisms
- Microbial Natural Products and Biosynthesis
- Agricultural Practices and Plant Genetics
- Pharmacological Effects of Natural Compounds
- Plant Micronutrient Interactions and Effects
- Photosynthetic Processes and Mechanisms
- Agricultural pest management studies
- Cannabis and Cannabinoid Research
- Bioenergy crop production and management
- Bioactive natural compounds
- Arsenic contamination and mitigation
- Aluminum toxicity and tolerance in plants and animals
- Natural product bioactivities and synthesis
Academy of Scientific and Innovative Research
2019-2025
Indian Institute of Integrative Medicine
2015-2025
Council of Scientific and Industrial Research
2009-2021
University of Jammu
2020
National Botanical Research Institute
2008-2016
Indian Institute of Science Bangalore
2004-2011
Flavonoids synthesized by the phenylpropanoid pathway participate in myriad physiological and biochemical processes plants. Due to diversity of secondary transformations complexity regulation branched pathways, single gene strategies have not been very successful enhancing accumulation targeted molecules. We expressed an Arabidopsis (Arabidopsis thaliana) transcription factor, AtMYB12, tobacco (Nicotiana tabacum), which resulted enhanced expression genes involved pathway, leading severalfold...
Flavonoids, due to their pharmacological attributes, have recently become target molecules for metabolic engineering in commonly consumed food crops. Strategies including expression of single genes and gene pyramiding provided only limited success, principally the highly branched complex biosynthetic pathway flavonoids. Transcription factors been demonstrated as an efficient tool this pathway, but often exhibit variation heterologous systems relative that homologous system. In present work,...
Summary Isoflavones, a group of flavonoids, restricted almost exclusively to family Leguminosae are known exhibit anticancerous and anti‐osteoporotic activities in animal systems have been target for metabolic engineering commonly consumed food crops. Earlier efforts based on the expression legume isoflavone synthase ( IFS ) genes nonlegume plant species led limited success terms content transgenic tissue due limitation substrate enzyme. In this work overcome limitation, activation multiple...
Plants synthesize secondary metabolites, including flavonoids, which play important role during various stresses for their survival. These metabolites are also considered as health-protective components in functional foods. Flavonols, one of the groups apart from performing several roles plants have been recognized potent phytoceuticals human health. Tomato fruits deficient this group flavonoids and an target enhancing accumulation flavonols through genetic manipulations. In present study,...
Accumulation of arsenic (As) in rice (Oryza sativa L.) grain is a serious concern worldwide. Long-term exposure to As affects nutritional status and associated with higher rates skin, bladder, lung cancers, heart disease. Genotypic variations for accumulation or tolerance are prevalent regulated by genetic environmental factors. To understand molecular networks involved accumulation, genome-wide expression analysis was performed roots low- high-As accumulating genotypes (LARGs HARGs). Six...
The homedodomain zipper family (HD-ZIP) of transcription factors is present only in plants and plays important role the regulation plant-specific processes. subfamily IV HDZ (HD-ZIP IV) has primarily been implicated epidermal structure development. Though this gene all lineages land plants, members have not identified banana, which one major staple fruit crops. In work, we 21 HDZIV genes banana by computational analysis genome resource. Our suggested that these putatively encode proteins...
Abstract The multidrug and toxic compound extrusion (MATE) protein family has been implicated in the transport of a diverse range molecules, including specialized metabolites. In tobacco (Nicotiana tabacum), only limited number MATE transporters have functionally characterized, no transporter studied context flavonoid this plant species so far. present study, we characterize two homeologous genes, NtMATE21 NtMATE22, demonstrate their role flavonol growth development. expression these genes...
Certain plants of the daily human diet are an important source beneficially healthy flavonoids, possessing significant pharmacological activities against various diseases. Flavonoids display array chemical diversity based on relative positioning benzopyrano moiety and aromatic ring. Due to structural these molecules, simultaneous quantification molecules in plant materials becomes difficult. In present study, a rapid, simple, sensitive, High Performance Liquid Chromatography-Photo Diode...
CYP2E1 plays a crucial role in the bio-activation of toxic substances leading to liver damage. In this context, converts paracetamol (PCM) N-acetyl-p-benzoquinone imine (NAPQI), which is prone cause hepatotoxicity. Hence, we aimed explore protective effect glabridin on widely used PCM-induced injury model present study and, after that, correlated with toward its efficacy. Glabridin was isolated from Glycyrrhiza glabra and characterized before investigation an in-vivo mice injury. oral...