A5103094502- Cancer Immunotherapy and Biomarkers
- Hepatocellular Carcinoma Treatment and Prognosis
- Inflammatory Biomarkers in Disease Prognosis
- Ferroptosis and cancer prognosis
- Cancer-related molecular mechanisms research
- Liver Disease Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Cancer, Hypoxia, and Metabolism
- Circular RNAs in diseases
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Heavy Metals in Plants
- Gastric Cancer Management and Outcomes
- Lung Cancer Research Studies
- Medical Imaging Techniques and Applications
- Immune cells in cancer
- Industrial Gas Emission Control
- Traditional Chinese Medicine Studies
- Advanced Materials and Mechanics
- Pancreatic and Hepatic Oncology Research
- Cancer Mechanisms and Therapy
- RNA modifications and cancer
- Additive Manufacturing and 3D Printing Technologies
- MRI in cancer diagnosis
- Cancer, Lipids, and Metabolism
- Liver Disease and Transplantation
Huazhong University of Science and Technology
2000-2025
Union Hospital
2022-2025
State Key Laboratory of Information Engineering in Surveying Mapping and Remote Sensing
2022-2025
Southern University of Science and Technology
2021-2024
Union Hospital
2023-2024
Jinan University
2018-2024
National Central University
2024
Okayama University
2023
Wuhan Union Hospital
2023
Fujian Medical University
2023
To evaluate the efficacy and safety of transarterial chemoembolization (TACE) combined with camrelizumab (hereafter, TACE-camrelizumab) in treatment patients recurrent hepatocellular carcinoma (R-HCC) after curative resection.R-HCC who underwent TACE plus or TACE-alone from January 2016 to August 2021 were retrospectively evaluated. Patients assessed for tumor response, progression-free survival, survival rates adverse events.Seventy-one included this study, including 20 TACE- group 51...
Objectives To compare the safety and efficacy of lenvatinib (LEN) combined with camrelizumab plus transcatheter arterial chemoembolization (TACE-LEN-C) TACE LEN (TACE-LEN) in patients unresectable hepatocellular carcinoma (uHCC). Methods Eighty-three uHCC treated TACE-LEN-C or TACE-LEN from September 2018 to May 2021 were enrolled this retrospective study. Overall survival (OS), progression-free (PFS), local tumor response, adverse events (AEs) evaluated. Univariate multivariate analyses...
Well-performing organic–inorganic halide perovskites are susceptible to poor efficiency and instability due their various defects at the interphases, grain boundaries (GBs), surfaces. In this study, an in situ method is utilized for effectively passivating under-coordinated Pb2+ of perovskite with new non-fullerene acceptors (NFAs) (INXBCDT; X = H, Cl, Br) through carbonyl cyano functional groups during antisolvent dripping process. It reveals that bicyclopentadithiophene (BCDT) core highly...
Immune checkpoint inhibitors (ICIs) have contributed to a significant advancement in the treatment of cancer, leading improved clinical outcomes many individuals with advanced disease. Both preclinical and investigations shown that ICIs are associated atherosclerosis other cardiovascular events; however, exact mechanism underlying this relationship has not been clarified.
The steady-state multiplicity in azeotropic distillation processes has been theoretically predicted and verified experimentally for decades. However, it is a tough task to detect all the solutions. purpose of this article 2-fold: first, provides systematical study on homogeneous with intermediate entrainer novel strategy proposed find solutions using "Design Specs/Vary" Aspen Plus. Operating unstable branch benefits both energy saving reducing capital investment product quality specified....
At present, immunotherapy has become a powerful treatment for advanced gastric cancer (AGC), but not all patients can benefit from it. According to the latest research, impact of B cell subpopulations on immune microenvironment (GC) is unknown. Exploring whether interaction between cells and tumor in GC affects effectiveness attracted our interest.
Worldwide use and disposal of plastics have reached a dramatic saturation point, polluting lands, oceans, air across the globe. Responding to such challenge requires, among other environmental remediation measures, manufacture alternative sustainable plastics. Recent studies in area enabled development degradable plastics; however, rate conditions required for degradation materials remains under scrutiny. Here, we introduce new class fully plant-based, rapidly lignin zein composite blend...
The hypoxic microenvironment and inflammatory state of residual tumors caused by insufficient radiofrequency ablation (iRFA) are major reasons for rapid tumor progression pose challenges immunotherapy. We retrospectively analyzed the clinical data patients with hepatocellular carcinoma (HCC) treated RFA observed that iRFA was associated poor survival outcomes progression-free survival. Using an orthotopic HCC mouse model a colorectal liver metastasis model, we treatment melatonin after...
This study aimed to explore the prognostic value of bone marrow cellularity in clinical outcomes patients with cervical cancer treated programmed cell death protein-1 (PD-1) inhibitors. retrospectively included locally advanced or receiving PD-1 inhibitor monotherapy combination other therapies at Wuhan Union Hospital from May 2020 December 2023. The mean signal intensity left posterior iliac bone, cerebrospinal fluid, and subcutaneous fat regions were measured on T1-weighted magnetic...
This study aimed to investigate whether extracellular volume (ECV) fraction derived from equilibration contrast-enhanced computed tomography (CECT) affects prognosis in HCC patients receiving ICIs. retrospective ultimately included 211 undergoing ICIs, of whom 60 were an internal validation assess the reproducibility results. Baseline unenhanced and equilibrated CECT used measure CT values tumor, liver aorta, which combined with hematocrit calculate ECV fraction. Correlation analysis was...
The spleen serves as an important immune organ which influences the anti-tumor response by modulating microenvironment. This study investigated prognostic impact of volume (SV) on survival in hepatocellular carcinoma (HCC) patients receiving checkpoint inhibitors (ICIs). retrospective included 224 HCC treated with ICIs, categorized into Higher and Lower SV groups median further increased Non-SV based changes at 3 months after ICIs. Kaplan-Meier curves Cox regression models were used to...
Colorectal cancer (CRC) was one of the most commonly diagnosed malignancies. The molecular mechanisms involved in progression CRC remain unclear. Accumulating evidences showed that long noncoding RNAs (lncRNAs) played key roles tumorigenesis, progression, and metastasis. Therefore, we aimed to explore lncRNAs CRC.In this study, identify differentially expressed messenger (mRNAs) by analyzing a cohort previously published datasets: GSE64857. GO KEGG pathway analyses were applied give us...
Gastric cancer is one of the most common malignancies in China and exhibits a poor prognosis. The significant challenge for gastric treatment absence early diagnostic biomarkers. MicroRNAs (miRNAs) are small non-coding RNAs, which possess clinical value number different types cancer. current study identified 13 miRNAs (hsa-miR-22, hsa-miR-545, hsa-let-7i, hsa-miR-15b, hsa-miR-221, hsa-miR-196a, hsa-miR-20a, hsa-miR-196b, hsa-miR-93, hsa-miR-19a, hsa-miR-503, hsa-miR-106b hsa-miR-18a) that...
Hodgkin lymphoma (HL) is a type of common throughout the western countries. However, detailed mechanisms and special biomarkers HL remain to be further investigated. Emerging studies have shown that long non-coding RNAs play key role in human cancers.In present work, we constructed relapse-related lncRNA-mediated ceRNA networks HL. Additionally, co-expression for these lncRNAs. We also lncRNA-miRNA-mRNA network study potential mechanism Furthermore, gene ontology (GO) Kyoto Encyclopedia...
Abstract Difficult laparoscopic cholecystectomy (DLC) is difficult to precisely predict before operation. This observational cohort study aimed evaluate the predictive value of procalcitonin (PCT) for DLC in patients with acute cholecystitis (AC). A total 115 were included from January 2017 April 2018. Multiple logistic regression and receiver-operating characteristic (ROC) performed PCT levels DLC. Patients had significantly higher Tokyo Guidelines 2018 (TG18) grade ( P = 0.002) C-reactive...
Abstract Background Although numerous studies have reported the prognostic value of lung immune index (LIPI) in non-small cell cancer (NSCLC) patients treated with checkpoint inhibitors (ICIs), LIPI a pancancer setting remains unclear. Methods A comprehensive search was conducted until July 2023 across PubMed, Embase, Web Science, and Cochrane Library databases to identify relevant evaluating ICIs. The outcomes were overall survival (OS), progression-free (PFS), objective response rate...