- Medicinal Plant Pharmacodynamics Research
- Ginseng Biological Effects and Applications
- Psoriasis: Treatment and Pathogenesis
- Dermatology and Skin Diseases
- Pomegranate: compositions and health benefits
- Asthma and respiratory diseases
- Vector-borne infectious diseases
- Epigenetics and DNA Methylation
- Analytical Chemistry and Chromatography
- Insect Resistance and Genetics
- Analytical Methods in Pharmaceuticals
- Probiotics and Fermented Foods
- Liver Disease Diagnosis and Treatment
- Tryptophan and brain disorders
- Plant Stress Responses and Tolerance
- Plant-based Medicinal Research
- Ziziphus Jujuba Studies and Applications
- Pharmaceutical studies and practices
- Alcohol Consumption and Health Effects
- Ginkgo biloba and Cashew Applications
- Urticaria and Related Conditions
- Insect and Pesticide Research
- MicroRNA in disease regulation
- Alkaloids: synthesis and pharmacology
- Glutathione Transferases and Polymorphisms
Beijing University of Chemical Technology
2024-2025
Northwest A&F University
2025
Nanjing Medical University
2025
Jiangsu Province Hospital
2025
Southern Medical University
2023-2025
Nanfang Hospital
2023-2025
University of Nebraska Medical Center
2020-2024
National University of Singapore
2024
XinHua Hospital
2024
Shanghai Jiao Tong University
2024
Berberine (BBR) has been confirmed to have multiple bioactivities in clinic, such as cholesterol-lowering, anti-diabetes, cardiovascular protection and anti- inflammation. However, BBR’s plasma level is very low; it cannot explain its pharmacological effects patients. We consider that the vivo distribution of BBR well bioactive metabolites might provide part explanation for this question. In study, liquid chromatography coupled ion trap time-of-flight mass spectrometry (LC/MSn-IT-TOF) with...
Generalized pustular psoriasis (GPP) is a rare and severe inflammatory skin disease that can be life-threatening. Gene mutations are found in some cases, but its immune pathogenesis largely unknown. Here, we observed the neutrophil:lymphocyte ratio patients with GPP was higher than healthy controls decreased after effective treatment. Neutrophils isolated from induced expressions of genes including IL-1β, IL-36G, IL-18, TNF-α, C-X-C motif chemokine ligands keratinocytes normal neutrophils...
Resistive switching memories have garnered significant attention due to their high-density integration and rapid in-memory computing beyond von Neumann's architecture. However, challenges are posed in practical applications with respect manufacturing process complexity, a leakage current of high resistance state (HRS), the sneak-path problem that limits scalability. Here, mild-temperature thermal oxidation technique for fabrication low-power ultra-steep memristor based on Ag/TiO
Sulfonated polystyrene-b-polyisobutylene-b-polystyrene copolymers (SSIBS) with various average molar percentages of sulfonic acid side groups based on all the structural units along SSIBS polymer chains (SP) were synthesized via sulfonation SIBS acetyl sulfate. A transmission electron microscopy (TEM) method was developed to directly observe dark phase –(SO3)2Pb ionic channels ion clusters by exchange H+ Pb2+. The size hydrophilic in enlarged increasing SP and desired interconnected...
Inspired by the maxillary mouthparts of longicorn beetles, four types bionic cutters were designed in this research to address prevalent issues high cutting resistance and severe stubble damage encountered during alfalfa harvesting. Finite element simulation was utilized assess structural integrity performance these cutters. Additionally, bench tests conducted on a homemade stem-cutting force measurement control rig evaluate their effectiveness. The results indicated: (1) achieved reduction...
Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide and third cause of cancer-related deaths. Currently available treatment options for HCC patients are scarce resulting in an urgent need to develop a novel effective cure. Polygonum capitatum medicinal herb which has been used treat inflammatory diseases Miao nationality China. We recently isolated pure compound davidiin from P. extract. Four cell lines were treated with davidiin. Cell viability was recorded by MTT...
Significance Two of the most debilitating and scientifically challenging diseases 21st century are cancer neurodegeneration. Although results from excessive cell growth, neurodegeneration is a consequence loss. Dysfunction same key regulators, including oncogenes tumor suppressors, may cause both diseases. We report that LPS IFN induce apoptosis-stimulating protein p53 with signature sequences ankyrin repeat-, SH3 domain-, proline-rich region-containing 2 (ASPP2) transcription through signal...
Co-relation between allergic asthma and microbiota varying with diet has been extensively investigated, implicating that oral supplement of alternative pharmaceuticals are potential for control. Probiotics great concern due to its beneficial effects on the host, whereas mechanisms optimal dose need be further explored. In present study, three different doses mixed strains were given orally mouse model induced by ovalbumin (OVA). Continuous administration probiotics could alleviate...
Abstract The novel chemically stable hybrid co‐networks (PTA‐Fe) of poly(thioctic acid) coordinated with molar content ( C Fe ) 1%∼12% 3+ generated from [FeCl 4 ·POH] − can be in situ synthesized via controlled/living cationic ring‐opening polymerization α ‐thioctic acid (TA) tert ‐butyl chloride(BCl)/FeCl 3 /isopropanol(POH) initiating system at 0 °C. polymerizations are all first order respect to monomer, initiator and co‐initiator. resulting PTAs desired molecular weights relatively...