A5024399841- Photodynamic Therapy Research Studies
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Medical and Biological Ozone Research
- NF-κB Signaling Pathways
- Phosphorus and nutrient management
- Occupational exposure and asthma
- Cancer Research and Treatments
- Prostate Cancer Treatment and Research
- Heavy metals in environment
- Cytokine Signaling Pathways and Interactions
- Genomics, phytochemicals, and oxidative stress
- Inflammasome and immune disorders
- Ubiquitin and proteasome pathways
- Water Quality and Pollution Assessment
- Psoriasis: Treatment and Pathogenesis
- Cancer-related gene regulation
- Adenosine and Purinergic Signaling
- Nanoplatforms for cancer theranostics
- Immune Response and Inflammation
Chinese Academy of Medical Sciences & Peking Union Medical College
2021-2025
Tianjin Third Central Hospital
2024-2025
Tianjin Medical University
2018-2025
Tianjin Fire Research Institute
2025
Tianjin International Joint Academy of Biomedicine
2025
Neusoft (China)
2022
Logistics University of People's Armed Police Force
2019
Chinese People's Armed Police Force
2019
Acute lung injury (ALI) is a major cause of morbidity and mortality globally, characterized by widespread inflammation in the lungs. Increased production reactive oxygen species hypothesized to be associated with ALI. Matrine lycopene are active products present traditional Chinese medicine. an effective inhibitor inflammation, whereas decreases lipid peroxidation. Therefore, it was that combinatorial treatment matrine may provide synergistic protection against In study, mice were treated...
Ulcerative colitis (UC) is an inflammatory bowel disease characterized by inflammation and ulceration of the digestive tract. Photodynamic therapy (PDT) with a novel photosensitizer LD4 was used to treat UC rat models explore therapeutic effect mechanism LD4-PDT on UC. 16S ribosomal RNA detect composition Gut microbiota. Our findings indicate that could protect integrity colonic mucosa, alleviate response promote healing mucosa. Mechanism studies demonstrated inhibit NF-κB signaling pathway,...
Ulcerative colitis (UC), a chronic, nonspecific inflammatory bowel disease characterized by continuous and diffuse changes in the colonic mucosa, requires novel treatment method. Photodynamic therapy (PDT), as promising physico-chemical method, were used to treat UC rats' model with photosensitizer LD4 this paper, effect mechanism was investigated. LD4-PDT could improve survival rate of 2,4,6-trinitrobenzene sulfonic acid (TNBS)-induced rats, decrease expression interleukin (IL)-6, IL-1,...
As heavy metals are easy to accumulate and have strong biological toxicity, they pose a potential threat human health by entering the body through cumulative effect of marine life. Land-based input is an important source in ocean, which has great influence on coastal water quality. In this study, spatial distribution characteristics (Zn, Cu, Cd, Pb, Cr, As) waters desulfurization process outlet power plant Zhanjiang Bay were investigated, enrichment behavior organisms (oysters barnacles)...
As a potent inhibitor of 17α-hydroxylase/C17, 20-lyase (CYP17), Abiraterone (Abi) can significantly inhibit the growth prostate cancer cells. Abi-DTPA, new water-soluble derivative Abi synthesized in our laboratory，which showed more efficacy than that abiraterone. The current study aims to investigate their differences between and its derivativein pharmacokinetics, tissue distribution, excretion male rats. A sensitive rapid high-performance liquid chromatography tandem mass spectrometric...