Abstract We report the prevalence rates for dementia and Alzheimer's disease (AD) obtained from a probability sample survey of 5,055 noninstitutionalized older persons in Shanghai, China. A two‐stage procedure was used case finding identification. Chinese version Mini‐Mental State Examination to determine cases possible dementia. Three different cutoff points on this mental status test were depending respondent's level education. Clinical evaluations, based functional assessments psychiatric...

The field of psychiatric epidemiology continues to employ self-report instruments, but the low degree agreement between diagnoses achieved using these instruments vs. that by psychiatrists in clinical modality threatens credibility results.In Baltimore Epidemiologic Catchment Area follow-up, 349 individuals who had a Diagnostic Interview Schedule (DIS) interview were blindly examined Schedules for Clinical Assessment Neuropsychiatry (SCAN). Comparisons made at level diagnosis, syndrome, and...

A comprehensive genetic diversity analysis of 87 Passiflora germplasm accessions domesticated and cultivated for several years in the karst region Guizhou, China, was conducted utilizing simple sequence repeat (SSR) fluorescent markers. These species, renowned their culinary medicinal value, could bring significant economic ecological benefits to region. This study aimed assess resources these species facilitate selection superior cultivars adapted environment. Our revealed an abundance SSR...

This study addressed the incidence of obsessive-compulsive disorder (OCD) in adults general population. The Baltimore cohort 3481 subjects, originally sampled during 1981 multisite Epidemiologic Catchment Area Study, was traced. From 1993 to 1996, 1920 people were reinterviewed using Diagnostic Interview Schedule. DSM-III-R estimated at .55 per 1000 person-years. There a relatively high rate new cases elderly women. It appeared that there two peaks onset OCD over life span, both which occur...

Vagus nerve stimulation inhibits proinflammatory cytokine production by signaling through the alpha7 nicotinic acetylcholine receptor (alpha7nAChR). Anisodamine, a muscarinic antagonist, has been used clinically in China for treatment of various shocks, but mechanism was poorly understood. Here, we tested hypothesis whether anisodamine attained its antishock effect activation alpha7nAChR.: Randomized and controlled vitro vivo study.Research laboratory animal facility rooms.Sprague-Dawley...

Background The objective is to estimate parameters of the natural history panic disorder, including its prodrome, incidence, recovery and recurrence. Method In 1981 Baltimore Epidemiologic Catchment Area Study interviewed 3481 individuals probabilistically selected from household population. During 1993–1996, 1920 these (73% survivors) were again. Baseline follow-up interviews included National Institute Mental Health Diagnostic Interview Schedule. follow-up, a subsample was assessed by...

In this work, we aimed to investigate the frequency, possible categories and clinical significance of circulating CD4 + ICOS FoxP3 T cells in patients with systemic lupus erythematosus (SLE). The frequency was analysed by flow-cytometric analysis 32 SLE patients, 10 rheumatoid arthritis healthy controls. Production IL-10 mTGF-β different T-cell populations determined intracellular cytokine staining. Plasma levels TGF-β were enzyme-linked immunosorbent assay (ELISA). significantly increased...

The passion fruit (Passiflora edulis Sims), also known as the purple granadilla, is widely cultivated new darling of market throughout southern China. This exotic and perennial climber adapted to warm humid climates, thus generally intolerant cold. There limited information about gene regulation signaling pathways related cold stress response in this species. In study, two transcriptome libraries (KEDU_AP vs. GX_AP) were constructed from aerial parts cold-tolerant cold-susceptible varieties...

Soil organic carbon (SOC) forms the largest terrestrial (C) pool, which is regulated by complex connections between exogenous C input, microbial activity, and SOC conversion. Few studies have examined changes in natural abundance due to activity after inputs karst lime soils China. In this research, 13C isotope tracer technique was employed investigate priming effect of on typical soil (0~20 cm) 13C_litter 13C_calcium carbonate (CaCO3) through a mineralization incubation experiment. Samples...

Objectives This study was designed to evaluate the interaction between aging and obesity on cardiac contractile intracellular Ca2+ properties. Methods Cardiomyocytes from young (4-mo) (12- 18-mo) male lean leptin deficient ob/ob obese mice were treated with (0.5, 1.0 50 nM) for 4 hrs in vitro. High fat diet (45% calorie fat) receptor mutant db/db models at older age used comparison. Cardiomyocyte properties evaluated including peak shortening (PS), maximal velocity of...

Department of Mental Hygiene; School Hygiene and Public Health; Johns Hopkins University; Baltimore, Maryland

1. The present study was designed to investigate the haemodynamic features and morphological changes in experimentally hypertensive rat models. 2. Sprague-Dawley rats were used prepare models, including two-kidney, one-clip renovascular (2K1C) rats, deoxycorticosterone acetate salt (DOCA) N(G)-nitro-l-arginine methyl ester-induced (l-NAME) rats. Six weeks after induction of hypertension, 24 h blood pressure recorded variability (BPV) expressed by (or 12 daytime night-time study) standard...

Precipitation variation under global climate change condition exacerbates the challenges in vegetation restoration and management arid semiarid regions. The response of plant water use to precipitation is not well understood for Caragana korshinskii, a kind dominant xerophytic shrub species that widely cultivated on Chinese Loess Plateau soil conservation. Thus, we investigated sap flow (SF) C. korshinskii rainout-shelter simulated regimes: 30% reduction (P-30%), control (CK), increase...

The predator-prey-type ecosystem is investigated, taking into account the time-delay effect of prey population on predator population, as well random variations in birth rate and death predators. stochastic averaging procedure applied to obtain probability distributions populations at state statistical stationarity. It found that two system parameters, quantifying effects self-competition time delay, respectively, play most important roles. Results are also obtained from Monte Carlo...

Neufeld KJ, Swartz KL, Bienvenu OJ, Eaton WW, Cai G. Incidence of DISIDSM‐IV social phobia in adults. Acta Psychiatr Scand 1999: 100: 186–192. © Munksgaard 1999. Objective: The aim the study was to estimate incidence general population. Method: Baltimore cohort 3481 subjects, sampled during 1981 Epidemiologic Catchment Area study, traced. A total 1920 subjects were re‐interviewed from 1993 1996 using Diagnostic Interview Schedule (DIS). subsample 349 interviewed by psychiatrists Schedules...

Background. Ketanserin, a 5-hydroxytryptamine receptor antagonist, is clinically used as an antihypertensive agent and could enhance baroreflex function. The present work tested the hypothesis that restoration of function effective treatment for lipopolysaccharide (LPS)–induced shock.