A5029581300- Machine Learning in Bioinformatics
- Microbial infections and disease research
- Protein Hydrolysis and Bioactive Peptides
- Antimicrobial Peptides and Activities
- Microbial Metabolic Engineering and Bioproduction
- Aquaculture disease management and microbiota
- Bacteriophages and microbial interactions
- Biochemical and Structural Characterization
- vaccines and immunoinformatics approaches
- Fungal Biology and Applications
- Amphibian and Reptile Biology
- Fungal and yeast genetics research
- Biochemical Analysis and Sensing Techniques
- Plant Virus Research Studies
- Metabolomics and Mass Spectrometry Studies
- Genomics and Phylogenetic Studies
- Computational Drug Discovery Methods
- Comparative Animal Anatomy Studies
- Fermentation and Sensory Analysis
- Lipid metabolism and biosynthesis
- Analytical Chemistry and Chromatography
- Meat and Animal Product Quality
- Bone Tissue Engineering Materials
- Viral Infectious Diseases and Gene Expression in Insects
- Bone and Dental Protein Studies
Kasetsart University
2016-2025
Chalmers University of Technology
2010-2013
We here present simple and rapid methods for fast screening of yeast lipids in Saccharomyces cerevisiae. First we introduced a microwave-assisted technique lipid extraction that allows the within 10 min. The new method enhances rate by 27 times, while maintaining product yields comparable to conventional (n = 14, P > 0.05). recovery 3) from spiking synthetic standards were 92 ± 6% cholesterol, 95 4% triacylglycerol, free fatty acids. Additionally, combines cell disruption one step, approach,...
Abstract The voltage-gated sodium (Na v ) channel is a crucial molecular component responsible for initiating and propagating action potentials. While the α subunit, forming pore, plays central role in this function, complete physiological function of Na channels relies on interactions between subunit auxiliary proteins, known as protein–protein (PPI). blocking peptides (NaBPs) have been recognized promising alternative therapeutic agent pain itch. Although traditional experimental methods...
Hyperpigmentation is a medical and cosmetic problem caused by an excess accumulation of melanin or the overexpression enzyme tyrosinase, leading to several skin disorders, i.e., freckles, melasma, cancer. Tyrosinase key in melanogenesis thus target for reducing production. Although abalone good source bioactive peptides that have been used properties including depigmentation, available information on anti-tyrosinase property remains insufficient. This study investigated Haliotis diversicolor...
Gastropods are among the most diverse animals. Gastropod mucus contains several glycoproteins and peptides that vary by species habitat. Some bioactive from gastropod were identified only in a few species. Therefore, using biochemical, mass spectrometric, bioinformatics approaches, this study aimed to comprehensively identify putative proteomes of seven commonly found or commercially valuable gastropods. The was collected triplicate samples, proteins separated 1D-SDS-PAGE before tryptic...
The development of anticancer nanomedicine using semiconductor photocatalysts has received tremendous attention owing to their simultaneous therapeutic as well diagnostic potential. Hence, such nanomaterials are considered promising theranostic agents. In the present study, ZnO NPs doped with Ag/Er were fabricated hydrothermally. ZnOAg NPs, ZnOEr and ZnOAgEr exhibited absorption peaks at 366 nm, 369 365 respectively while showed a distinct peak 361 nm in UV-visible spectra. particles mostly...
Abstract Accurate identification of angiotensin‐I‐converting enzyme (ACE) inhibitory peptides is essential for understanding the primary factor regulating renin‐angiotensin system and guiding development new drug candidates. Given inherent challenges in experimental processes, computational methods silico peptide can be invaluable enabling high‐throughput characterization ACE peptides. This study introduces GRU4ACE, an innovative deep learning framework based on multi‐view information...
Dipeptidyl peptidase-IV (DPPIV) inhibitory peptides are a class of antihyperglycemic drugs used in the treatment type 2 diabetes mellitus, metabolic disorder resulting from reduced levels incretin hormone GLP-1. Given that DPPIV degrades incretin, key regulator blood sugar levels, various antidiabetic medications inhibit DPPIV, such as vildagliptin, sitagliptin, and linagliptin, employed. However, potential side effects these remain matter debate. Therefore, we aimed to investigate...
Background/Objectives: Limosilactobacillus fermentum KUB-D18, a heterofermentative lactic acid bacterium with promising probiotic properties, is known for promoting gut health and nutrient absorption. Originally isolated from chicken intestines, this strain demonstrates versatile metabolic capabilities in diverse gastrointestinal environments. However, the functions sugar transport-related genes remain largely unexplored. This study thus aimed to dissect transports of L. KUB-D18. Methods:...
Abstract Background Tyrosinase is an enzyme involved in melanin production the skin. Several hyperpigmentation disorders involve overproduction of and instability tyrosinase activity resulting darker, discolored patches on Therefore, discovering inhibitory peptides (TIPs) great significance for basic research clinical treatments. However, identification TIPs using experimental methods generally cost-ineffective time-consuming. Results Herein, a stacked ensemble learning approach, called...
In the yeast Saccharomyces cerevisiae, genes containing UASINO sequences are regulated by Ino2/Ino4 and Opi1 transcription factors, this regulation controls lipid biosynthesis. The expression level of INO2 INO4 (INO-level) at different nutrient limited conditions might lead to various responses in metabolism. study, we undertook a global study on how INO-levels (transcription INO4) affect metabolism also studied effects single double deletions two INO-genes (deficient effect). Using 2 types...
Dental pulp tissue contains stem cells that can be isolated and used for regenerative medicine in tooth restoration or autologous transplantation. The aim of this study was to observe the mineralization gene expression dental (DPCs) following treatment with snail mucus. Snail mucus collected from adult Achatina fulica processed as a dry powder by freeze-drying technique. dissolved culture medium at concentration 15 μg/mL. DPCs were prepared outgrowth technique cultured 6-well plate density 5...
Metabolic footprinting offers a relatively easy approach to exploit the potentials of metabolomics for phenotypic characterization microbial cells. To capture highly dynamic nature metabolites, we propose use metabolic instead traditional method which relies on analysis at single time point. Using direct infusion-mass spectrometry (DI-MS), could observe in yeast S. cerevisiae BY4709 (wild type) cultured 3 different C-sources (glucose, glycerol, and ethanol) sampled along 10 points with 5...
Plant-allergenic proteins (PAPs) have the potential to induce allergic reactions in certain individuals. While these are generally innocuous for majority of people, they can elicit an immune response those with particular sensitivities. Thus, screening and prioritizing allergenic plant is indispensable development diagnostic tools, therapeutic interventions or medications treat reactions. However, investigating based on experimental methods costly labour-intensive. Therefore, we develop...