- Protein Hydrolysis and Bioactive Peptides
- Antimicrobial Peptides and Activities
- Mosquito-borne diseases and control
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Viral Infections and Vectors
- Advanced Proteomics Techniques and Applications
- Peptidase Inhibition and Analysis
- Insect Utilization and Effects
- Meat and Animal Product Quality
- Invertebrate Immune Response Mechanisms
- Malaria Research and Control
- GABA and Rice Research
- Aquaculture Nutrition and Growth
- Gut microbiota and health
- Plant Stress Responses and Tolerance
- Probiotics and Fermented Foods
- Aquaculture disease management and microbiota
- Biochemical and Structural Characterization
- Photosynthetic Processes and Mechanisms
- MicroRNA in disease regulation
- Metabolomics and Mass Spectrometry Studies
- Plant-Microbe Interactions and Immunity
- Oral microbiology and periodontitis research
- Phytase and its Applications
- Antibiotic Resistance in Bacteria
National Science and Technology Development Agency
2016-2025
National Center for Genetic Engineering and Biotechnology
2016-2025
Kasetsart University
2019-2024
Advanced Neural Dynamics (United States)
2023
National Centre for Genetic Resources and Biotechnology
2013-2023
Prince of Songkla University
2022
Centro de Ingeniería Genética y Biotecnología
2016-2022
Thammasat University
2022
Phramongkutklao Hospital
2022
Hebei Academy of Agriculture and Forestry Sciences
2020
Abstract Chikungunya virus (CHIKV) has recently re‐emerged causing millions of infections in countries around the Indian Ocean. While CHIKV a broad host cell range and productively infects number different types, macrophages have been identified as potential viral reservoir serving to increase duration symptoms. To date no interacting protein characterized this study sought identify binding proteins expressed on target membranes. Two‐dimensional overlay prohibitin (PHB) microglial protein....
Abstract Chikungunya virus (CHIKV) is a re-emerging mosquito-borne alphavirus that has recently engendered large epidemics around the world. There no specific antiviral for treatment of patients infected with CHIKV and development compounds significant anti-CHIKV activity can be further developed to practical therapy urgently required. Andrographolide derived from Andrographis paniculata , herb traditionally used treat number conditions including infections. This study sought determine...
Pigmented rice (Oryza sativa L.) is recognized as a source of natural antioxidant compounds, such flavonoids, oryzanol, tocopherol, and anthocyanin. Because their nutritional benefits, anthocyanin-enriched or pigmented varieties are feasible alternatives for promoting human health. Pigment biosynthesis in complex process that involves multiple biosynthetic regulatory genes. This study aimed to identify the genes associated with traits local Thai develop molecular markers breeding programs....
Abstract Phytophthora palmivora, an oomycete pathogen, induces leaf fall disease in rubber trees (Hevea brasiliensis), causing significant economic losses. Effective management requires understanding metabolic dynamics during infection. This study employed untargeted metabolomic and proteomic analyses to investigate the response of seedling leaves P. palmivora Metabolomic profiling revealed 1702 979 metabolite peaks positive negative ionization modes, respectively, with 212 metabolites...
Our previous research demonstrated the health benefits of sericin-derived oligopeptides (SDOs) from yellow silk cocoons, particularly their hypoglycemic and antihypertensive properties. This study aims to produce SDOs at a pilot scale, preparing them for large commercial production as novel food ingredient, investigates impact scale-up on characteristics specifications. We compared productivity generated 25 L 300 batches via hydrolysis sericin using 5% Neutrase (E/S) 50 °C 4 h. The scale...
Background Tilapia Lake virus (TiLV) poses a significant threat to global tilapia aquaculture, causing high mortality rates and severe economic losses. However, the molecular mechanisms underlying TiLV-host interactions remain largely unexplored. Methodology We investigated proteomic phosphoproteomic changes in two piscine cell lines, E-11 RHTiB cells, following TiLV inoculation at different time points. Differential protein expressions 10-min 24-h post infection were selected for...
Background/Objective: Ferroptosis is an iron-dependent form of programmed cell death characterized by lipid peroxidation products (LPOs). A chemotherapeutic drug, 5–fluorouracil (5–FU), can induce epithelial mucositis and favor drug synergism with erastin in ferroptosis. Camellia tea saponin extract (TS) known to exert antioxidative properties. This study aims delineate the protective role TS mitigating 5–FU-induced ferroptosis inflammation human keratinocytes. Methods: HaCaT cells were...
Research in metagenomics and metaproteomics can reveal how microbiological interactions fermented foods contribute to their health benefits. This study examined three types of vegetables: a standard formulation, probiotic formulation with Lacticaseibacillus rhamnosus GG, polyphenol vitexin from Mung bean seed coat. Measurements were taken at day 0 (after 36 h fermentation room temperature) after 15 days. We applied 16S rRNA sequencing evaluate microbial diversity utilized LC-MS/MS...
BACKGROUND: Fish collagen has been paid increasing attention as an alternative to the mammalian counterpart owing abundance of fish skin a processing by-product. Generally, low yield extracted using typical acid solubilisation process led use pepsin aid for yield. Alternatively, pepsin, especially from tuna stomach, can be used extraction pepsin-solubilised (PSC). Therefore objective this study was extract and characterise PSC bigeye snapper, widely surimi production in Thailand. RESULTS:...
The mosquito transmitted Dengue virus (DENV) remains a significant public health problem in many tropical and subtropical countries. Increasing evidence has suggested that during the infection process cellular lipids play important roles at several stages of replication cycle. This study sought to characterize changes lipid metabolism gene expression investigated role one enzyme, fatty acid synthase, DENV infection. Transcriptional profiles genes associated with were evaluated by real-time...
Monoclonal antibodies with specific antigens have been widely used as targeted therapy for cancer. Hep88 mAb is a monoclonal antibody which shows binding anti-cancer effects against the HepG2 cell line. However, its mechanisms of action are still not completely understood. We examined cycling and apoptosis by flow cytometry mRNA expression factors involved in paraptosis mAb-treated cells real-time PCR. The cell-cycle analysis demonstrated that growth-inhibitory activity was associated G2/M...