A5019986040- Pancreatic and Hepatic Oncology Research
- Cancer Genomics and Diagnostics
- Renal cell carcinoma treatment
- Gastric Cancer Management and Outcomes
- Neuroendocrine Tumor Research Advances
- Cancer Diagnosis and Treatment
- Colorectal Cancer Treatments and Studies
- Esophageal and GI Pathology
- Pediatric Hepatobiliary Diseases and Treatments
- Metastasis and carcinoma case studies
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Cardiac tumors and thrombi
- Esophageal Cancer Research and Treatment
- Gastrointestinal Tumor Research and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Tracheal and airway disorders
- Gastrointestinal disorders and treatments
- Vascular Procedures and Complications
- Connective tissue disorders research
- Aortic aneurysm repair treatments
- Colorectal and Anal Carcinomas
- Cancer Cells and Metastasis
- Vascular Tumors and Angiosarcomas
- Intraperitoneal and Appendiceal Malignancies
- Sarcoma Diagnosis and Treatment
Japanese Foundation For Cancer Research
2018-2025
Nagoya University
2022-2025
The Cancer Institute Hospital
2021
Cancer Institute (WIA)
2018
Anjo Kosei Hospital
2016-2017
Importance Preoperative chemo(radio)therapy is increasingly used in patients with localized pancreatic adenocarcinoma, leading to pathological complete response (pCR) a small subset of patients. However, multicenter studies in-depth data about pCR are lacking. Objective To investigate the incidence, outcome, and risk factors after preoperative chemo(radio)therapy. Design, Setting, Participants This observational, international, cohort study assessed all consecutive pathology-proven...
Objective: To propose a shared T classification system for biliary cancers located around the cystic duct junction. Summary Background Data: These include perihilar cholangiocarcinoma (PCC), distal (DCC), and carcinoma (CDC), which are staged according to discrete tumor classification. Methods: From 2011 2019, patients with that clinically invaded junction (junctional [JCC] ) were classified as having PCC, DCC, CDC, or unclassifiable (UT) based on topologic predominance. The prognostic...
Metastatic gastric tumor originating from breast cancer (MGTBC) is rare. Endoscopically, (GC)-like lesions and submucosal tumors (SMT) are the features of MGTBC. Their clinicopathological characteristics currently uncertain. We analyzed 11 patients with MGTBC to better understand disease progression thereby improve early detection methods.From 2006 2016, diagnosed by esophagogastroduodenoscopy (EGD) were included.All women, a median age 57 years. Histological examination revealed six cases...
<h3>Abstract</h3> Background/Aim: Carbohydrate antigen 19-9 (CA19-9) levels may aid in the determination of subsequent treatment patients with unresectable locally-advanced pancreatic cancer (LAPC) treated chemotherapy. However, relationship between timing and magnitude CA19-9 changes clinical outcomes remains unclear. This study was conducted to identify changes, which are most strongly associated LAPC patients. Patients Methods: We retrospectively analyzed consecutive gemcitabine plus...
An 82-year-old woman with common bile duct (CBD) dilatation observed during routine ultrasonography was referred to our hospital. Preliminary blood tests revealed elevated levels of hepatobiliary enzymes. Computed tomography (CT) scan showed lower wall thickening and enhancement. Esophagogastroduodenoscopy mildly swollen papilla Vater, without ulceration. Endoscopic retrograde cholangiography demonstrated that the CBD grossly dilated a constriction in part. The final diagnosis indicated...
Colorectal cancer (CRC) with lung metastases has an unfavorable prognosis. However, nowadays, even advanced CRC can have a favorable outcome in certain cases. A complete response (CR) is rare event metastases. Herein, we report 2 cases of attaining CR.Case 1 was 58-year-old man who underwent laparoscopic ileocecal resection for cecum multiple to the lungs 2011. We performed treatment mFOLFOX6 and bevacizumab chemotherapy August After 11 courses, computed tomography (CT) revealed CR February...
812 Background: Several studies have reported that patients with right-sided colon cancers (RCC) more unfavorable responses to anti-epidermal growth factor receptor (EGFR) antibody therapy than those left-sided (LCC). One of the causes is RCC frequently genetic mutations such as RAS, BRAF, and PIK3CA LCC. We investigated clinical outcomes treated anti-EGFR in later line without these mutations. Methods: reviewed 653 cases colorectal cancer from October 2009 July 2017. There were 150...
Abstract A 53-year-old man with prior history of resection liposarcoma in his leg presented gallbladder mass. Computed tomography showed 4-cm tumor at fundus weak enhancement IV contrast. Differential diagnoses included hemangioma and liposarcoma, laparoscopic cholecystectomy was recommended. In the operating room, appeared without serosal liver invasions uncomplicated completed. Histopathological examination revealed as myxoid round cells. Adjuvant chemotherapy not given, he placed on...
今回，われわれは動静脈瘻を合併した腸骨動脈瘤をステントグラフト留置術にて治療し，良好な経過が得られたため報告する．58歳，男性．右下肢浮腫を主訴に当科を受診した．理学所見として右下肢の腫脹と右鼠径部の圧痛を認めた．下肢超音波検査にて，右大腿静脈に動脈拍動性のシグナルがあり，動静脈瘻を示唆する所見であった．造影CT検査で，径70mm大の右総腸骨動脈瘤を認めた．総腸骨静脈と連続し，静脈は早期濃染され，動静脈瘻を合併した右総腸骨動脈瘤破裂と診断した．緊急で右内腸骨動脈コイル塞栓術，右腸骨動脈ステントグラフト留置術を施行した．術後第5病日，CT検査で動静脈瘻は消失していたが，右腸骨静脈血栓が出現したため抗凝固療法を開始し，14病日目に退院となった．その後，フォローのCT検査で腸骨静脈の血栓は消失し，瘤も血栓化し縮小した．
Gastric cancer with paraaortic lymph node (PAN) metastasis have unfavorable prognosis. There are no evidence-based preoperative chemotherapy regimens available. A 62-year-old female was diagnosed advanced gastric and PAN metastasis. We attempted S-1/CDDP in six coursed total gastrectomy as well systematic dissection of regional nodes PAN. Histologically, cancerous cells were detected specimens. The patient has been disease-free for 5 years since the surgery. Long-term survival case attaining...
症例は85歳の男性で，2010年7月脳梗塞で入院した際に貧血を指摘された．精査の腹部CTで小腸腫瘍による腸重積を認めた．腹部症状に乏しく，その後，重積は自然解除し，高齢であること，再発脳梗塞の急性期であること，低心機能であることなどから，手術は行わず経過観察となった．2012年5月，再び腹痛が出現した．腹部CTでは，腸重積を同じ部位に認めた．重積の原因である小腸腫瘍は増大していた．2年前と比較して，腫瘍は増大したものの切除可能であり，心機能が改善したこと，脳梗塞後の後遺症もほぼなくADLは良好であることから，手術を施行した．開腹すると，空腸起始部から約270 cmの小腸に腫瘍による腸重積を認めた．小腸部分切除術を施行した．切除標本では，小腸内腔へ突出した6×4 cm大の腫瘍を認めた．病理組織学的には紡錘形の異型細胞の増殖像を認め，免疫組織化学染色検査でα-smooth muscle actinは陽性，KIT，CD34，S-100は陰性を示し，小腸平滑筋肉腫と診断した．術後は順調に経過し，腸重積による発症から50か月後，肺炎による他病死に至るまで再発することなく良好な転帰が得られた．