Giuseppe Coppola

ORCID: 0000-0003-3080-407X
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About
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Research Areas
  • Cardiac pacing and defibrillation studies
  • Cardiac Arrhythmias and Treatments
  • Cardiovascular Health and Disease Prevention
  • Cardiovascular Disease and Adiposity
  • Adipokines, Inflammation, and Metabolic Diseases
  • Cerebrovascular and Carotid Artery Diseases
  • Cardiac electrophysiology and arrhythmias
  • Atrial Fibrillation Management and Outcomes
  • Peripheral Artery Disease Management
  • Cardiovascular Function and Risk Factors
  • Cardiac Imaging and Diagnostics
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Cardiac Structural Anomalies and Repair
  • Acute Myocardial Infarction Research
  • Lipoproteins and Cardiovascular Health
  • Cardiac Valve Diseases and Treatments
  • Blood Pressure and Hypertension Studies
  • Cardiomyopathy and Myosin Studies
  • Cardiac, Anesthesia and Surgical Outcomes
  • Coronary Interventions and Diagnostics
  • Atherosclerosis and Cardiovascular Diseases
  • Cardiovascular Effects of Exercise
  • Aortic Disease and Treatment Approaches
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Congenital Heart Disease Studies

Azienda Ospedaliera Universitaria Policlinico "Paolo Giaccone" di Palermo
2016-2025

Ospedale Monaldi
2025

Azienda Ospedaliera Bolognini Seriate
2025

Azienda Ospedaliera Universitaria Pisana
2025

Ospedale Santa Maria
2025

University of Palermo
2012-2024

Agostino Gemelli University Polyclinic
2014-2024

Ospedale dei Pellegrini
2013-2023

Ospedale G.F. Ingrassia
2023

Fondazione Poliambulanza Istituto Ospedaliero
2023

This comprehensive review explores the various scenarios of atherosclerosis, a systemic and chronic arterial disease that underlies most cardiovascular disorders. Starting from an overview its insidious development, often asymptomatic until it reaches advanced stages, delves into pathophysiological evolution atherosclerotic lesions, highlighting central role inflammation. Insights clinical manifestations, including heart attacks strokes, highlight disease’s significant burden on global...

10.3390/ijms25116016 article EN International Journal of Molecular Sciences 2024-05-30

We assessed the role of glucose and insulin in regulation circulating levels soluble intercellular adhesion molecule-1 (sICAM-1) vascular (sVCAM-1) normal subjects patients with type 2 diabetes.Plasma concentrations were acutely raised 10 newly diagnosed, complication-free diabetic maintained at 15 mmol/L for hours. In subjects, plasma sICAM-1, but not sVCAM-1, rose significantly (P<0.01) 1 hour returned to basal values another study, octreotide was infused during hyperglycemic clamp block...

10.1161/01.cir.101.19.2247 article EN Circulation 2000-05-16

Background The purpose of this study was to investigate whether the vasodilator response brachial artery and presence carotid lesions may have a prognostic significance in patients with early stages atherosclerosis. Methods results Vascular echography performed analyze flow-mediated vasodilatation (FMD) at intima–media thickness (IMT) arteries 84 asymptomatic patients. At baseline, we evaluated all established traditional cardiovascular risk factors. Transient ischemic attack, stroke, effort...

10.1097/mca.0b013e3282f3fbde article EN Coronary Artery Disease 2008-05-01

The need for unobtrusive HR (heart rate) monitoring has led to the development of a new generation strapless monitors. aim this study was determine whether such an unobtrusive, wrist-worn optical monitor (OHRM) could be equivalent and therefore valid alternative traditional chest strap during broad range activities in heterogeneous healthy population coronary artery disease (CAD) patients. One hundred ninety-nine volunteers, 84 males 115 females, including 35 overweight-obese subjects, 53...

10.1186/s13102-018-0098-0 article EN cc-by BMC Sports Science Medicine and Rehabilitation 2018-05-31

Aortic stenosis (AS) is a common valvular heart disease in the Western populations, with an estimated overall prevalence of 3% adults over 75 years. To understand its patho-biological processes represents priority. In elderly patients, AS usually involves trileaflet valves and referred to as degenerative calcific processes. Scientific evidence suggests involvement active "atherosclerosis-like" pathogenesis initiation phase AS. contrary, progression could be driven by different forces (such...

10.11909/j.issn.1671-5411.2016.06.001 article EN PubMed 2016-09-01

Artificial Intelligence (AI) made its first appearance in 1956, and since then it has progressively introduced itself healthcare system patients’ information care. AI functions can be grouped under the following headings: Machine Learning (ML), Deep (DL), Neural Network (ANN), Convolutional (CNN), Computer Vision (CV). Chronic limb-threatening ischemia (CLTI) represents last stage of peripheral artery disease (PAD), increased over recent years, together with rise prevalence diabetes...

10.20944/preprints202401.1008.v1 preprint EN 2024-01-12

BackgroundShort-term (within 6 weeks follow-up) clinical studies indicate that implantation of bone marrow cells (BMCs) into ischemic limbs may improve peripheral ischemia. Here, the long-term safety and feasibility intraarterial autologous BMCs with oral treatment antioxidants L-arginine were investigated in patients critical ischemia on account advanced atherosclerotic arterial disease (PAD).

10.1097/hjr.0b013e3283193a0f article EN European Journal of Cardiovascular Prevention & Rehabilitation 2008-11-26

Cardiovascular diseases in women still rises and remains their leading cause of death most developed countries; yet we have less sex-specific data than men as a result lower enrollment clinical trials low rates reporting. The aim our study was to evaluate hypertensive postmenopausal the potential predictive role markers inflammation, for example, fibrinogen C-reactive protein (CRP), on subclinical atherosclerosis, beyond that other established cardiovascular risk factors. We studied 127...

10.1097/mca.0b013e3283109065 article EN Coronary Artery Disease 2008-12-05
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