A5033504848- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- SARS-CoV-2 and COVID-19 Research
- COVID-19 and healthcare impacts
- Pneumonia and Respiratory Infections
- Tuberculosis Research and Epidemiology
- COVID-19 and Mental Health
- Respiratory viral infections research
- HIV-related health complications and treatments
- Pneumocystis jirovecii pneumonia detection and treatment
- Infectious Diseases and Tuberculosis
- Influenza Virus Research Studies
- Healthcare Systems and Practices
- HIV Research and Treatment
- Intensive Care Unit Cognitive Disorders
- Pituitary Gland Disorders and Treatments
- Immune Cell Function and Interaction
- HIV/AIDS Research and Interventions
- Antibiotic Use and Resistance
- interferon and immune responses
- Sepsis Diagnosis and Treatment
- Viral Infections and Outbreaks Research
- Herpesvirus Infections and Treatments
- Peripheral Neuropathies and Disorders
- Adrenal Hormones and Disorders
Assistance Publique – Hôpitaux de Paris
2009-2024
Hôpital Ambroise-Paré
2009-2024
Université Paris-Saclay
2024
Johns Hopkins Hospital
2024
All India Institute of Medical Sciences Raipur
2023
All India Institute of Medical Sciences Rishikesh
2023
Université de Versailles Saint-Quentin-en-Yvelines
2020-2022
CHU Ambroise Paré
2014-2021
University of Oxford
2021
Laboratoire Vision Action Cognition
2017
In addition to hemostasis, human platelets have several immune functions and interact with infectious pathogens including HIV in vitro. Here, we report that from HIV-infected individuals on combined antiretroviral drug therapy (ART) low blood CD4+ T cell counts (<350 cells/μl) contained replication-competent despite viral suppression. vitro, harboring propagated the virus macrophages, a process could be prevented biologic abciximab, an anti-integrin αIIb/β3 Fab. Furthermore, our cohort, 88%...
Immunological non-responders (InRs) are HIV-infected individuals in whom the administration of combination antiretroviral therapy (cART), although successful suppressing viral replication, cannot properly reconstitute patient circulating CD4 + T-cell number to immunocompetent levels. The causes for this immunological failure remain elusive, and no therapeutic strategy is available restore a proper immune response these individuals. We have recently demonstrated that platelets harboring...
BackgroundFollowing a study of predictors superinfection in viral respiratory tract infections (VRTIs), this analyzes the outcome.MethodsMulticenter retrospective conducted among adults who tested positive for VRTIs with reverse-transcription polymerase chain reaction. We compared characteristics between influenza virus, Paramyxoviridae, and Pneumoviridae identified favorable short-term outcome, admission to intensive care unit (ICU), mortality.ResultsA total 590 patients had VRTI, including...
COVID-19 is a major pandemic with potential cardiovascular complications. Few studies have focused on electrocardiogram (ECG) modifications in patients.We reviewed from our database all patients referred to hospital for between January 1st, 2020, and December 31st, 2020: 669 were included 98 died (14.6%). We systematically analyzed ECG at admission during hospitalization if available. was abnormal 478 (71.4%) more frequently who did not survive (88.8 vs. 68.5%, p < 0.001). The most common...
Abstract Background Influenza‐like illness (ILI) incidence estimates in individuals treated with immunosuppressants and/or biologics corticosteroid for an autoimmune or chronic inflammatory disease are scarce. We compared the ILI among immunocompromised population and general population. Method conducted a prospective cohort study during 2017–2018 seasonal influenza epidemic, on GrippeNet.fr electronic platform, which allows collection of epidemiological crowdsourced data ILI, directly from...
Abstract Background Viral respiratory tract infections (VRTIs) are among the most common diseases, but risks of superinfection for different virus species have never been compared. Methods Multicenter retrospective study conducted adults who tested positive VRTIs with reverse-transcription polymerase chain reaction. We compared characteristics between influenza (A or B) and paramyxoviruses (respiratory syncytial virus, parainfluenza types 1 3, human metapneumovirus) identified predictors...