A5088186418- Cardiac pacing and defibrillation studies
- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiac electrophysiology and arrhythmias
- Acute Myocardial Infarction Research
- Cardiac Imaging and Diagnostics
- Cardiovascular Function and Risk Factors
- Heart Failure Treatment and Management
- Angiogenesis and VEGF in Cancer
- ECG Monitoring and Analysis
- Cardiac Structural Anomalies and Repair
- Coronary Interventions and Diagnostics
- Cardiomyopathy and Myosin Studies
- Lipoproteins and Cardiovascular Health
- Blood Pressure and Hypertension Studies
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Congenital Heart Disease Studies
- Diabetes Management and Research
- Pulmonary Hypertension Research and Treatments
- Transplantation: Methods and Outcomes
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac Fibrosis and Remodeling
- Cardiovascular Disease and Adiposity
- Congenital heart defects research
- Cerebrovascular and Carotid Artery Diseases
Hospitais da Universidade de Coimbra
2015-2024
University of Coimbra
2014-2024
Hospital de Santa Marta
2024
Sociedade Portuguesa de Cardiologia
2022
University of Beira Interior
2022
Escola Superior de Tecnologia da Saúde de Coimbra
2019-2021
Association for Innovation and Biomedical Research on Light and Image
2015-2016
Universidad San Pablo CEU
2013
Florida Certification Board
2001
American Association for the Study of Liver Diseases
1995
The goal of this study was to develop a risk score model for patients with Brugada syndrome (BrS).Risk stratification in BrS is significant challenge due the low event rates and conflicting evidence.A multicenter international cohort no previous cardiac arrest used evaluate role 16 proposed clinical or electrocardiogram (ECG) markers predicting ventricular arrhythmias (VAs)/sudden death (SCD) during follow-up. Predictive were incorporated into model, validated by using out-of-sample...
Some patients show such an important clinical improvement and reverse remodelling after cardiac resynchronization therapy (CRT) that anatomy function approach normal. These have been called 'super-responders'. The aim of our study was to identify predictors becoming a super-responder CRT. Eighty-seven consecutive who underwent CRT were prospectively studied. Before 6 months after, echocardiographic evaluation performed. Patients with decrease in New York Heart Association functional class...
Diabetic patients have a significantly worse prognosis after an acute myocardial infarction (AMI) than their counterparts. Previous studies shown that the number of circulating endothelial progenitor cells (EPCs) increase early AMI in normoglycemic patients. However, it is well known type 2 diabetes mellitus (DM) associated with impaired function and reduced EPCs levels. Nonetheless, few analyzed response diabetics to EPC pre-diabetic has not been reported yet. Therefore, we hypothesized...
Introduction and Objectives: Atrial fibrillation (AF) heart failure (HF) often coexist. AF catheter ablation improves left ventricular ejection fraction (LVEF), but its impact varies between patients. We aimed to identify predictors of LVEF improvement in HF patients with impaired undergoing ablation. Methods: conducted a retrospective single-center study <50% May 2016 2022. The primary endpoint was the recovery rate ('responders'). Secondary endpoints were one-year safety effectiveness....
Burnout Syndrome is a psychological condition characterized by chronic work-related stress. This studys main objective was to analyze the prevalence of in nursing professionals at Hospital Sanatorio do Kuito-Bie. To this end, quantitative methodology adopted, descriptive and comparative nature, with non-experimental cross-sectional design. The sampling used non-probabilistic for convenience, encompassing 16 professionals, which 10 were women (62.5%) 6 men (37.5%), aged between 26 51 years....
Resumo Fundamento: O software ablation index (AI) permitiu melhorar os resultados da ablação de fibrilação atrial (FA), mas as taxas recorrência permanecem significativas. Biomarcadores séricos específicos têm sido associados a essa recorrência. Objetivos: Avaliar se certos biomarcadores podem ser utilizados (individualmente ou combinados) para predizer FA pós guiada pelo AI. Métodos: Estudo multicêntrico, observacional, prospectivo pacientes consecutivos, encaminhados janeiro 2018 março...
Abstract Aims We aimed to assess the acute and midterm efficacy of premature ventricular contraction (PVC) ablation guided by multielectrode point-by-point (PbP) mapping. Methods results This is a retrospective, international multicentre study consecutive patients referred for PVC in 10 hospital centres from January 2017 December 2021. Based on mapping approach, two cohorts were identified: ‘Multipolar group’, where dedicated high-density catheter was employed, ‘PbP performed with catheter....
Abstract Background T cells have been implicated in the development and progression of inflammatory processes chronic heart failure (CHF). Cardiac resynchronization therapy (CRT) has beneficial effects on symptoms cardiac remodeling CHF. However, its impact immune response remains controversial. We aimed to study CRT (HF) patients. Methods Thirty-nine HF patients were evaluated before (T0) six months later (T6). Quantification cells, their subsets, functional characterization, after vitro...
Anemia has been shown to be associated with a worse prognosis, especially higher mortality in various pathological conditions. However, few studies have specifically examined its impact acute coronary syndrome (ACS) patients. The purpose of our study was assess the association between different quartiles hemoglobin on admission and short- long-term prognosis patients ACS. We performed retrospective analysis 1303 consecutive ACS admitted care unit analyzed baseline morbidity mortality,...
Background It would be important to better identify heart failure (HF) patients most likely respond cardiac resynchronization therapy (CRT). Because endothelial progenitor cells (EPCs) play a crucial role in the maintenance of vascular endothelium integrity, we hypothesize that who have higher circulating EPCs levels greater neovascularization potential and are more prone responders CRT. Methods Prospective study 30 consecutive patients, scheduled for Echocardiographic evaluation was...
Os anticoagulantes orais demonstraram ser altamente eficazes na prevenção do acidente vascular cerebral (AVC) associado a fibrilhação auricular (FA). A ocorrência de AVC apesar da hipocoagulação oral não é expectável, existindo escassa informação sobre os mecanismos responsáveis pela sua ocorrência. O objetivo deste estudo foi avaliar possíveis para isquémico, como má adesão à terapêutica e adequação dosagem dos em doentes cronicamente hipocoagulados por FA. Estudo prospetivo observacional,...
Usher Syndrome (USH) is a rare disease with hearing loss, retinitis pigmentosa and, sometimes, vestibular dysfunction. A phenotype heterogeneity reported. Recent evidence indicates that USH likely to belong an emerging class of sensory ciliopathies. Olfaction has recently been implicated in ciliopathies, but the scarce literature about olfaction show conflicting results. We aim evaluate olfactory impairment as possible clinical manifestation USH. Prospective study included 65 patients and...
Abstract Background Recent studies suggest that circulating endothelial progenitor cells (EPCs) may influence the response to cardiac resynchronization therapy (CRT). The aim of this study was evaluate effect CRT on EPC levels and assess impact EPCs long-term clinical outcomes. Population methods Prospective 50 patients submitted CRT. Two populations were quantified previously implantation: CD34 + KDR CD133 cells. reassessed 6 months after Endpoints during follow-up all-cause mortality,...
A anemia tem sido associada a um pior prognóstico, e particularmente uma mortalidade mais elevada em diversas condições patológicas. Contudo, poucos estudos analisaram especificamente o seu impacto curto longo prazo, doentes com Síndrome Coronária Aguda. Este artigo como objetivo analisar associação entre diferentes quartis de hemoglobina na admissão hospitalar prognóstico prazo síndrome coronária aguda. Estudo retrospetivo 1303 consecutivamente admitidos aguda numa unidade cuidados...