A5077617439- Adenosine and Purinergic Signaling
- Pulmonary Hypertension Research and Treatments
- Neuroinflammation and Neurodegeneration Mechanisms
- Congenital Heart Disease Studies
- Congenital heart defects research
- Medical Device Sterilization and Disinfection
- Listeria monocytogenes in Food Safety
- Clostridium difficile and Clostridium perfringens research
- Poxvirus research and outbreaks
- Healthcare Systems and Practices
- Herpesvirus Infections and Treatments
- Neuropeptides and Animal Physiology
- Bacterial Identification and Susceptibility Testing
- Immune cells in cancer
- Tracheal and airway disorders
- Renal Transplantation Outcomes and Treatments
- Enterobacteriaceae and Cronobacter Research
- Bacillus and Francisella bacterial research
- Tissue Engineering and Regenerative Medicine
- Vagus Nerve Stimulation Research
- Vascular Anomalies and Treatments
- Antibiotic Use and Resistance
- HIV/AIDS Impact and Responses
- Antibiotic Resistance in Bacteria
- Cardiac pacing and defibrillation studies
Centro Hospitalar de Lisboa Central
2022-2025
Hospital Curry Cabral
2022-2024
University of Coimbra
2014-2020
Hospitais da Universidade de Coimbra
2020
Weatherford College
2020
Monkeypox, a neglected and re-emergent zoonotic disease caused by monkeypox virus (MPXV) infection, has been endemic in Central Western Africa for decades. More recently, an outbreak spread to global level, occurring sites with no previous reported cases being clustered among men who have sex men, suggesting new modes of transmission. There is urgent need research better understanding the genomic evolution changing epidemiology Orthopoxvirus group. Our work aimed characterize clinical...
Microglia rely on their ability to proliferate in the brain parenchyma sustain innate immunity and participate reaction damage. We now studied influence of different danger signals activating microglia, both internal (typified by glutamate, associated with damage) external (using a bacterial lipopolysaccharide, LPS), proliferation microglia cells. found that LPS (100 ng/mL) increased, whereas glutamate (0.5 mM) decreased proliferation. Notably, increased extracellular levels ATP. In...
Background/Objectives: The timely initiation of antiretroviral therapy (ART) in persons living with HIV (PLWH) improves clinical outcomes. However, ART commencement is often delayed. Portugal, which has one the highest new diagnosis rates within European Union, limited available data. Evidence from 2017-2018 suggests that average time to exceeds recommendations for optimal benefits. This study aimed assess number days first hospital appointment among newly diagnosed PLWH Portugal between...
Introduction: Artificial intelligence is an area that has been transforming various sectors of society. One these tools ChatGPT (chat generative pre-trained transformer), a large language model-based platform developed to understand patterns and generate answers. The accessibility, answers in real-time, privacy make with enormous potential health counseling. aim this study was explore the counseling literacy regarding HIV infection pre-exposure prophylaxis (PrEP). Methods: A team five...
Abstract Background Recent studies suggest that circulating endothelial progenitor cells (EPCs) may influence the response to cardiac resynchronization therapy (CRT). The aim of this study was evaluate effect CRT on EPC levels and assess impact EPCs long-term clinical outcomes. Population methods Prospective 50 patients submitted CRT. Two populations were quantified previously implantation: CD34 + KDR CD133 cells. reassessed 6 months after Endpoints during follow-up all-cause mortality,...
Carbapenem-resistant Enterobacteriaceae (CRE) epidemiology among liver transplant (LT) recipients is variable. We studied the impact of CRE colonization and infection on LT recipients' outcomes. This observational cohort study included consecutive adult between January 2019 December 2020 at Curry Cabral Hospital, Lisbon, Portugal. Primary exposures were (rectal swabs under a screening program) within 1 year index LT. endpoint was graft failure Among 209 patients, median (interquartile range...
Listeriosis is a series of diseases caused by the bacteria Listeria monocytogenes. Typically presenting with mild symptoms diarrhea, fever, and myalgias, it can, in some cases, assume an invasive form systemic involvement. Cardiac involvement listeriosis rare, very few reports describing cardiac implantable electronic devices (CIED), which hampers development conclusive recommendations regarding CIED management or antibiotic courses. We present case 82-year-old woman who had pacemaker...
Abstract Background Recent studies suggest that circulating endothelial progenitor cells (EPCs) may influence the response to cardiac resynchronization therapy (CRT). The aim of this study was evaluate effect CRT on EPCs levels and assess impact long-term clinical outcomes. Population methods Prospective 50 patients submitted CRT. Two populations were quantified previously implantation: CD34 + KDR CD133 cells. reassessed 6 months after Endpoints during follow-up all-cause mortality, heart...
Abstract Background Recent studies suggest that circulating endothelial progenitor cells (EPCs) may influence the response to cardiac resynchronization therapy (CRT). The aim of this study was evaluate effect CRT on EPCs levels and assess impact long-term clinical outcomes. Population methods Prospective 50 patients submitted CRT. Two populations were quantified previously implantation: CD34 + KDR CD133 cells. reassessed 6 months after Endpoints during follow-up all-cause mortality, heart...