A5073949478- Salmonella and Campylobacter epidemiology
- Reproductive tract infections research
- Clostridium difficile and Clostridium perfringens research
- Antimicrobial Resistance in Staphylococcus
- Foot and Ankle Surgery
- Nosocomial Infections in ICU
- Antibiotic Resistance in Bacteria
- Bacterial Infections and Vaccines
- Bioactive Compounds and Antitumor Agents
- Pediatric health and respiratory diseases
- Fecal contamination and water quality
- Antimicrobial agents and applications
- Bacterial biofilms and quorum sensing
- Orthopedic Surgery and Rehabilitation
- Gut microbiota and health
- Retinal Imaging and Analysis
- Mosquito-borne diseases and control
- Syphilis Diagnosis and Treatment
- Tracheal and airway disorders
- Food Safety and Hygiene
- Sinusitis and nasal conditions
- Water Treatment and Disinfection
- Synthesis of Indole Derivatives
- Sports injuries and prevention
- Medical and Biological Ozone Research
National Institute of Health Dr. Ricardo Jorge
2013-2024
Hospital Israelita Albert Einstein
2024
Hospital de Santa Marta
2023
Instituto de Tecnologias Interativas
2022
Active Technologies (Italy)
2022
Tampere University
2021
Universidade Nova de Lisboa
2005-2010
West Nile virus (WNV) genomic RNA was detected by reverse transcription-polymerase chain reaction (RT-PCR) in six out of 57 mosquito pools collected Southern Portugal, during the summer 2004, yielding an infection rate (IR) 2.8/1,000 mosquitoes. Phylogenetic analysis a 217-nucleotide fragment NS5 coding region, amplified from Culex pipiens s.l. and univittatus unfed females, demonstrated close relationship with WNV strains circulating Mediterranean basin (Italy, 1998; France, 2000; Morocco,...
Background/Objectives: The timely initiation of antiretroviral therapy (ART) in persons living with HIV (PLWH) improves clinical outcomes. However, ART commencement is often delayed. Portugal, which has one the highest new diagnosis rates within European Union, limited available data. Evidence from 2017-2018 suggests that average time to exceeds recommendations for optimal benefits. This study aimed assess number days first hospital appointment among newly diagnosed PLWH Portugal between...
Abstract Purpose To determine the age‐ and sex‐specific prevalence of early late age‐related macular degeneration ( AMD ) in two P ortuguese population‐based samples to identify its risk factors. Population A population 6023 adults aged ≥55 years was recruited from primary healthcare units central region ortugal – one a coastal n = 3000) another an inland town 3023). Methods Cross‐sectional study. Participants were enrolled locations between ugust 2009 O ctober 2013. Responders underwent...
Central venous catheter-related bloodstream infection (CRBSI) is a huge public health concern with considerable impact on mortality and costs.A three-year observational study enrolling three tertiary hospitals located in Lisbon, Portugal, was designed to identify the major aetiological agents of CRBSI, their ability colonize central catheters antimicrobial resistance profiles.Aetiological CRBSI were identified by Vitek 2. Whole-genome sequencing used confirm most prevalent characterize...
Clostridium difficile infection (CDI) is the leading cause of healthcare-associated diarrhea, and several outbreaks with increased severity mortality have been reported. In this study we report a C. PCR ribotype 027 outbreak in Portugal, aiming to contribute better knowledge epidemiology agent Europe.Outbreak retrospective medical records active surveillance data all inpatients diagnosis CDI, from 1st January 31th December 2012, Portuguese hospital. isolates were characterized regarding...
Biofilm-associated infections are a public health concern especially in the context of healthcare-associated such as catheter-related bloodstream (CRBSIs). We evaluated biofilm formation and antimicrobials resistance (AMR) Enterobacter cloacae complex Candida parapsilosis co-isolated from CRBSI patient. Antimicrobial susceptibility central venous catheters (CVCs) hemoculture (HC) isolates was evaluated, including whole genome sequencing (WGS) resistome analysis evaluation gene expression to...
This study extensively analyzed campylobacteriosis surveillance in Portugal from 2009 to 2021, aiming investigate demographic shifts, seasonal variations, and antimicrobial resistance (AMR) within Campylobacter isolates. Surveillance network sentinel laboratory-based system data revealed a substantial under-notification of cases, suggesting an underestimated disease burden. Notification rates exhibited paradigm shift, with notable prevalence among the pediatric population, particularly...
Longitudinal mosquito surveys were carried out in southern Portugal from 2004 to 2007, a wetland area (Comporta, District of Setúbal) and around the perimeter dam irrigation plant that created largest artificial lake Europe, 250 km2 (Alqueva, Districts Évora Beja). Our aim was study diversity, abundance, seasonal dynamics mosquitoes, comparing these two different areas, screen mosquitoes for West Nile Virus (WNV), an arboviral agent already detected Portugal, because areas are populated with...
Genomic surveillance of SARS-CoV-2 in Portugal was rapidly implemented by the National Institute Health early stages COVID-19 epidemic, collaboration with more than 50 laboratories distributed nationwide.By applying recent phylodynamic models that allow integration individual-based travel history, we reconstructed and characterized spatio-temporal dynamics introductions dissemination Portugal.We detected at least 277 independent introductions, mostly from European countries (namely United...
Aeromonas spp. are environmental bacteria able to infect animals and humans. Here, we aim evaluate the role of biofilms in persistence freshwater. were isolated from water biofilm samples identified by Vitek-MS 16S rRNA sequencing. Antibiotic susceptibility profiles determined according EUCAST, a crystal violet assay was used assess assembly. MTT enumeration colony-forming units planktonic chlorination, respectively. Identification at species level challenging, suggesting need improve...
Neisseria gonorrhoeae , the bacterium responsible for sexually transmitted disease gonorrhoea, has shown an extraordinary ability to develop antimicrobial resistance (AMR) multiple classes of antimicrobials. With no available vaccine, managing N. infections demands effective preventive measures, antibiotic treatment and epidemiological surveillance. The latter two are progressively being supported by generation whole-genome sequencing (WGS) data on behalf national international surveillance...
Freshwater pollution is a huge concern. A study aiming to evaluate physico-chemical characteristics, microbiota, occurrence of two groups persistent environmental pollutants with similar chemical properties (polycyclic aromatic hydrocarbons- PAHs and microplastics - MPs) in Alqueva's surface water was performed during 2021. Water samples were collected at three spots related touristic activities (two beaches one marina) the Winter, Spring, Summer Autumn seasons. In addition, presence...
Multidrug-resistant bacteria are one of the current biggest threats to public health and responsible for most nosocomial infections. Herein, we report efficient facile synthesis antibacterial agents aminoalkylphenols, derived from 5-nitrosalicyladehyde prepared through a Petasis borono-Mannich multicomponent reaction. Minimum inhibitory concentrations (MICs) as low 1.23 μM chlorine derivative were determined multidrug-resistant Gram-positive bacteria, namely, Staphylococcus aureus...
The recent increase in community-acquired
In parks, ornamental waters of easy access and populated with animals are quite attractive to children yet might hide threats human health. The present work focuses on the microbiota a Lisboa park, characterized during 2015. results show dynamic integrating pathogens such as Klebsiella pneumoniae, Aeromonas spp. Enterobacter spp., also antibiotic resistant bacteria. K. pneumoniae were planktonic biofilm organized vitro showed an enhanced ability assemble at 25 °C than 37 °C. Bacteria...
Abstract We report a multidrug-resistant Neisseria gonorrhoeae exhibiting resistance to ceftriaxone and cefixime, isolated in Portugal 2019. Whole-genome sequencing was performed for typing identification of genetic determinants antimicrobial resistance. Because its susceptibility profile, awareness should be raised the circulation this strain.
Foodborne diseases are a serious public health concern, and food-producing animals major source of contamination.