A5019705938- Stress Responses and Cortisol
- Tryptophan and brain disorders
- Receptor Mechanisms and Signaling
- Neuropeptides and Animal Physiology
- Rock Mechanics and Modeling
- Silicon Carbide Semiconductor Technologies
- Geotechnical Engineering and Underground Structures
- High-Velocity Impact and Material Behavior
- Bone Metabolism and Diseases
- Health and Lifestyle Studies
- Composite Structure Analysis and Optimization
- Geotechnical Engineering and Soil Stabilization
- Semiconductor materials and devices
- Structural Behavior of Reinforced Concrete
- Advanced X-ray and CT Imaging
- Periodontal Regeneration and Treatments
- Edible Oils Quality and Analysis
- Engineering Structural Analysis Methods
- Transcranial Magnetic Stimulation Studies
- Structural Load-Bearing Analysis
- Fatigue and fracture mechanics
- Neuroendocrine regulation and behavior
- Laser Applications in Dentistry and Medicine
- Chemokine receptors and signaling
- Esophageal and GI Pathology
Fukuoka Dental College
2013-2025
Canon Medical Systems Corporation (Japan)
2021-2024
Canon (Japan)
2021-2024
Zeon (Japan)
2024
Oita University
1998-2023
National Institute of Technology, Kagoshima College
2011-2022
Hitachi High-Tech (Japan)
2021
Hitachi (Japan)
2021
Geospatial Information Authority of Japan
2020
Tokyo Institute of Technology
2019
Chiral discrimination of saturated hydrocarbons has been very difficult to establish, or not possible at all. The first chiral cryptochiral 5-ethyl-5-propylundecane 1, that is, (n-butyl)ethyl(n-hexyl)(n-propyl)methane, a quaternary hydrocarbon, which is known exhibit practically no detectable value optical rotation between 280 and 580 nm, accomplished by asymmetric autocatalysis pyrimidyl alkanol. absolute configuration 1 determined. In the presence (R)- (S)-1, reaction...
Excessive mechanical stress (MS) during hyperocclusion is known to result in disappearance of the alveolar hard line, enlargement periodontal ligament (PDL) space, and destruction bone, leading occlusal traumatism. We hypothesized that MS induces expression osteoclastogenesis-associated chemokines PDL tissue, resulting chemotaxis osteoclastogenesis examined effect on relationships between chemokine using vivo vitro models. In an model, intermittent stretching-induced was shown up-regulate CC...
Abstract Purpose The acquisition of osseointegration during implant therapy is slower and poorer in patients with diabetes compared healthy persons. serum concentration adiponectin type II lower than that persons via the suppression AMP-activated protein kinase (AMPK). Therefore, we hypothesized AMPK activation enhances bone formation around implants, resulting improved osseointegration. purpose this study was to evaluate impact on osteoblast differentiation its mechanism downstream...
Objective Although acute care hospitals address pneumonia through antibiotic therapy and provide in-hospital swallowing rehabilitation conducted by speech-language pathologists, post-discharge follow-up is often insufficient. In particular, limited attention given to monitoring the recurrence of status oral intake once residents return their nursing homes. The aim this study was determine benefits collaboration between homes for dysphagia whether tests are a predictor development pneumonia....
Purpose: The bone regenerative healing process is often prolonged, with a high risk of infection particularly in elderly and diseased patients. A reduction time usually requires mechanical stress devices, chemical cues, or laser/thermal therapies. Although these approaches have been used extensively for the time, exact mechanisms involved thermal stress-induced regeneration remain unclear. Methods: Photothermal (PTS) stimulation was carried out using novel photothermal device, composed an...
Flip-type n-channel implantation and epitaxial (IE)-IGBT on 4H-SiC carbon face with an p <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">++</sup> collector layer was investigated. In this study, we employed the IEMOSFET as a MOSFET structure original wet gate oxidation method, to realize high channel mobility. We were able achieve ultrahigh blocking voltage of more than 16 kV, extremely low forward drop 5 V at 100 A/cm...
Ultrahigh-voltage SiC flip-type n-channel implantation and epitaxial (IE)-IGBTs were developed, the static dynamic performance was investigated. A large device (8 mm × 8mm) with a blocking voltage greater than 16 kV achieved, an on-state current of 20 obtained at low (V on ) 4.8 V. R diff 23 mΩ·cm 2 V = In order to evaluate switching characteristics IE-IGBT, ultrahigh-voltage power modules assembled. chopper circuit configuration used IE-IGBT. Smooth turn-off waveforms successfully CE 6.5 I...
In order to examine the involvement of corticotropin-releasing hormone (CRF) receptor in formation anxiety, we investigated whether CRF antagonist CP-154,526 suppressed conditioned fear stress. First, rats were individually subjected 30 min footshock. Twenty-four hours after footshock, again placed chamber and observed for 5 without shock. was administered before placing again. After that, once more applying Administration both stress (placing inside cage but not footshock) actual footshock...
Abstract Cholecystokinin (CCK) is one of the most abundant neurotransmitter peptides in brain. CCK appears to play an important role neurobiology anxiety and panic disorders (PD) both humans animals. Recently, we reported that lack CCKAR had a significant anxiogenic‐like effect rats. In this study, investigate PD, compared gene PD patients normal controls. Subjects who fulfilled DSM‐IV criteria for were 17 males 26 females. The sequence containing Pst I polymorphic site boundary between...
Transient receptor potential type A 1 ( TRPA 1) is reported to be a C 2+ ‐permeable channel and activated by cold temperatures mechanical stimuli in the hair cells dorsal root ganglion. Using DNA microarray, we found that was significantly up‐regulated human periodontal ligament (h PDL ) 2 d after intermittent stimulation (i MS loading compared with unloaded cells. Although h are known respond induced occlusal force, little about expression functional role of these Therefore, investigated...
4H-SiC carbon face flip-type n-channel implantation and epitaxial (IE)-IGBT with an p <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">++</sup> substrate was developed its switching test carried out. We were able to achieve ultrahigh blocking voltage greater than 16 kV, extremely low V <inf xmlns:xlink="http://www.w3.org/1999/xlink">on</inf> (6.35 at 20 A), good temperature stability. The operation achieved by connecting three IGBTs in parallel,...
4H-SiC(000-1) C-face was oxidized in H 2 O and mixture gas (H rich wet ambient) for the first time. ambient formed by catalytic water vapor generator (WVG) system, where action instantaneously enhances reactivity between to produce O. The dependence of SiC oxidation rate on partial pressure investigated. We fabricated 4H-SiC MOS capacitor MOSFET re-oxidation following dry oxidation. density interface traps reduced channel mobility improved comparison with conventional
Repetitive transcranial magnetic stimulation (rTMS) has been shown to have a therapeutic effect on affective disorder and anxiety disorders. However, some reports linked rTMS significant increase in normal volunteers. This study investigates the of use acute chronic paroxetine treatment this animal model anxiety. In rats, for 10 days induced anxiety, as by elevated plus maze, black white box, conditioned fear tests. was suppressed chronic, but not acute, paroxetine. These results suggest...