Upconversion (UC) process in lanthanide-doped nanomaterials has attracted great research interest for its extensive biological applications vitro and vivo, benefiting from the high tissue penetration depth of near-infrared excitation light low autofluorescence background. However, 980 nm laser, typically used to trigger Yb(3+)-sensitized UC process, is strongly absorbed by water structures could cause severe overheating effect. In this article, we report extension spectrum shorter...

ConspectusRare earth (RE) materials, which are excited in the ultraviolet and emit visible light spectrum, widely used as phosphors for lamps displays. In 1960's, researchers reported an abnormal emission phenomenon where photons emitted from a RE element carried more energy than those absorbed, owing to sequential transfer between two ions—Yb3+-sensitized Er3+ or Tm3+—in solid state. After further study, named this upconversion (UC) emission. More recent approaches take advantage of...

Nanotransducer-impregnated self-organized helical superstructures are found to exhibit unprecedented reversible handedness inversion upon irradiation by the dual-wavelength near-infrared light. Upon laser at 808 nm, twist sense changes from right-handed left-handed through an achiral liquid-crystal phase, whereas its reverse process occurs 980 nm. As a service our authors and readers, this journal provides supporting information supplied authors. Such materials peer reviewed may be...

Upconversion luminescent nanoparticles (UCNPs) have been widely used in many biochemical fields, due to their characteristic large anti-Stokes shifts, narrow emission bands, deep tissue penetration and minimal background interference. UCNPs-derived multifunctional materials that integrate the merits of UCNPs other functional entities also attracted extensive attention. Here this paper we present a core–shell structured nanomaterial, namely, NaGdF4:Yb,Er@CaF2@SiO2-PS, which is fields...

Upconversion emissions from rare-earth nanoparticles have attracted much interest as potential biolabels, for which small particle size and high emission intensity are both desired. Herein we report a facile way to achieve NaYF(4):Yb,Er@CaF(2) (NPs) with (10-13 nm) highly enhanced (ca. 300 times) upconversion compared the pristine NPs. The CaF(2) shell protects ions leaking, when exposed buffer solution, ensures biological safety bioprobe applications. With NPs, HeLa cells were imaged low...

As chip multiprocessors (CMP) become the main trend in processor development, various power and thermal management strategies have recently been proposed to optimize system performance while controlling or temperature of a CMP stay below constraint. The availability per-core DVFS (dynamic voltage frequency scaling) also makes it possible develop advanced strategies. However, most existing solutions rely on open-loop search optimization with assumption that can be estimated accurately, others...

Efficient tailoring of upconversion emissions in lanthanide-doped nanocrystals is great significance for extended optical applications. Here, we present a facile and highly effective method to tailor the selectivity by engineering local structure lanthanides Na(x)REF(3+x) nanocrystals. The was achieved through precisely tuning composition nanocrystals, with different [Na]/[RE] ([F]/[RE]) ratio. It found that lattice parameter as well coordination number symmetry changed composition. A...

Today's data centers face two critical challenges. First, various customers need to be assured by meeting their required service-level agreements such as response time and throughput. Second, server power consumption must controlled in order avoid failures caused capacity overload or system overheating due increasing high density. However, existing work controls application-level performance separately, thus, cannot simultaneously provide explicit guarantees on both. In addition, control...

Upconversion (UC) luminescent lanthanide nanoparticles (LNPs) are expected to play an important role in imaging and photodynamic therapy (PDT) vitro vivo. However, with the absorption of UC emissions by photosensitizers (PSs) generate singlet oxygen ((1)O2) for PDT, signals from LNPs significantly weakened. It is activate another route track location during PDT process. In this work, Nd(3+)-sensitized dual-band visible near-infrared (NIR) under single 808 nm excitation were reported address...

Pancreatic cancer is one of the most aggressive tumors associated with a poor clinical prognosis, weakly effective therapeutic options. Therefore, there strong impetus to discover new targets in pancreatic cancer. In present study, we first demonstrated that TSPAN1 upregulated and depletion decreases cell proliferation vitro vivo. expression was correlated overall survival patients. Moreover, novel positive regulator macroautophagy/autophagy characterized by decreased LC3-II SQSTM1/p62...

Both power and performance are important concerns for enterprise data centers. While various management strategies have been developed to effectively reduce server consumption by transitioning hardware components lower-power states, they cannot be directly applied today's centers that rely on virtualization technologies. Virtual machines running the same physical correlated, because state transition of any component will affect application all virtual machines. As a result, reducing solely...

As chip multiprocessors (CMPs) become the main trend in processor development, various power and thermal management strategies have recently been proposed to optimize system performance while controlling or temperature of a CMP stay below constraint. The availability per-core dynamic voltage frequency scaling (DVFS) also makes it possible develop advanced strategies. However, most existing solutions rely on open-loop search optimization with assumption that can be estimated accurately,...

Photon upconversion emission in a series of Yb³⁺–Tb³⁺ and Yb³⁺–Eu³⁺ activated nanoparticles were investigated this study.

In order to study the influence of 0−50 vol % hydrogen addition on idle performance, an experimental research was conducted a six-cylinder throttle body injection natural gas engine. Experiments have been made under various excess air ratios and ignition timings. The results show that remarkably decreased CH4 emission whereas it had no significant effect reduction CO. NOx relatively low at compared other emissions. Hydrogen combined with timing retardation effective way reduce emission. COV...

Minimizing the energy consumption of data centers has been researched extensively. However, much less attention is given to a related but different research topic: minimizing electricity bill network by leveraging prices in geographical locations distribute workloads among those locations. Initial solutions this problem are oversimplified with an unrealistic assumption that huge power demands have no impact on prices. As result, they cannot be applied cloud-scale Internet expected grow...

// Cefan Zhou 1, 2 , Ming Wang 3 Li 4 Yi Zhang 1 Weiyong Liu 5 Wenying Qin Rong He Yang Lu Yefu Xing-Zhen Chen 6 Jingfeng Tang Institute of Biomedical and Pharmaceutical Sciences, Provincial Cooperative Innovation Center, College Bioengineering, Hubei University Technology, Wuhan, Hubei, China The State Key Laboratory Virology, Life Wuhan University, Department Clinical Laboratory, Renmin Hospital Animal Biosafety Level III at the Center for Experiment, Tongji Hospital, Medical Huazhong...

Abstract A visual gene‐detecting technique using nanoparticle‐supported gene probes is described. With the aid of gold 3′‐end–mercapto‐derivatized oligonucleotide serving as detection probe, and 5′‐end –amino‐derivatized immobilized on glass surface acting capturing target DNA was detected visually by sandwich hybridization based highly sensitive “nano‐amplification” silver staining. Different genotypes Hepatitis B C viruses in serum samples from infected patients were home‐made HBV, HCV,...

Today's data centers face two critical challenges. First, various customers need to be assured by meeting their required service-level agreements such as response time and throughput. Second, server power consumption must controlled in order avoid failures caused capacity overload or system overheating due increasing high density. However, existing work controls application-level performance separately thus cannot simultaneously provide explicit guarantees on both. This paper proposes...

As chip multiprocessors (CMP) become the main trend in processor development, various power and thermal management strategies have recently been proposed to optimize system performance while controlling or temperature of a CMP stay below constraint. The availability per-core DVFS (dynamic voltage frequency scaling) also makes it possible develop advanced strategies. However, most existing solutions rely on open-loop search optimization with assumption that can be estimated accurately, others...

Both power and performance are important concerns for enterprise data centers. While various management strategies have been developed to effectively reduce server consumption by transitioning hardware components lower states, they cannot be directly applied today's centers that rely on virtualization technologies. Virtual machines running the same physical correlated because state transition of any component will affect application all virtual machines. As a result, reducing solely based...

Abstract Persistent infection with high‐risk HPV, particularly Type HPV 16 and 18, is necessary in the development of cervical cancer, but apart from infection, other causative factors most cancers remain unknown. The aim this study was to determine prevalence 18 HSV 1 2 samples, assess role HSVs carcinogenesis. Two hundred thirty‐three healthy controls 567 cases (333 cervicitis, 210 intraepithelial neoplasia, 24 squamous cell carcinoma) exfoliative cells were tested for 16, 1, DNA using...

Abstract Pygo2 has been discovered as an important Wnt signaling component contributing to the activation of Wnt-target gene transcription. In present study, we that mRNA and protein levels were up-regulated in majority (152/209) human brain glioma tissues five cell lines significantly correlated with age, WHO tumor classification poor patient survival. The histone methyltransferase complex components (WDR5, Ash2 menin, but not CXCC1 or NCOA6) down-regulated at promoter loci target genes...