A5038107623- Topic Modeling
- Molecular Biology Techniques and Applications
- Text and Document Classification Technologies
- Sentiment Analysis and Opinion Mining
- AI in cancer detection
- Advanced Text Analysis Techniques
- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Ultrasound and Hyperthermia Applications
- Optimization and Search Problems
- Immune cells in cancer
- Auction Theory and Applications
- Scheduling and Optimization Algorithms
- Supply Chain and Inventory Management
- Natural Language Processing Techniques
- Image Processing Techniques and Applications
- Esophageal and GI Pathology
- Artificial Immune Systems Applications
- Cell Image Analysis Techniques
- Cervical Cancer and HPV Research
- Lung Cancer Diagnosis and Treatment
- Neonatal and fetal brain pathology
- ATP Synthase and ATPases Research
- Nanoplatforms for cancer theranostics
- Limits and Structures in Graph Theory
Chongqing Cancer Hospital
2024-2025
Chongqing University
2024-2025
Sichuan University
2024
Fuzhou University
2022-2023
Huaibei Normal University
2021-2022
University of California, Los Angeles
2022
Affiliated Hospital of Xuzhou Medical College
2014
Xuzhou Medical College
2014
The immunohistochemical (IHC) staining of the human epidermal growth factor receptor 2 (HER2) biomarker is widely practiced in breast tissue analysis, preclinical studies, and diagnostic decisions, guiding cancer treatment investigation pathogenesis. HER2 demands laborious chemical processing performed by a histotechnologist, which typically takes one day to prepare laboratory, increasing analysis time associated costs. Here, we describe deep learning-based virtual IHC method using...
Prostate cancer is one of the most prevalent malignancies in men. Once prostate advances to castration-resistant (CRPC), 5-year survival rate can decrease as low 14 months. However, current primary diagnostic method, PSA testing, associated with a lengthy detection cycle, limited accuracy, and delays identifying disease progression. Consequently, there an urgent need develop imaging technique that enables early accurate diagnosis CRPC. First, immunofluorescence was used verify expression...
This study aims to evaluate the potential of BST2-targeted microbubble-facilitated HIFU therapy for prostate cancer (PCa), and elucidate mechanisms synergistic tumor suppression in residual lesions. The specificity BST-2 expression PCa endothelial cells was established using a cellular co-culture method. targeting efficacy Anti-BST-2 antibody-conjugated microbubbles (BST-2-MB) evaluated both vitro vivo. therapeutic outcomes BST-2-MB-augmented (High-Intensity Focused Ultrasound) Balb/c mice...
Abstract Background Primary prostate cancer with metastasis has a poor prognosis, so assessing its risk of is essential. Methods This study combined comprehensive ultrasound features tissue proteomic analysis to obtain biomarkers and practical diagnostic image that signify metastasis. Results In this study, 17 benign prostatic hyperplasia (BPH), primary without (PPCWOM), (PPCWM) were comprehensively analyzed the corresponding proteome data perform weighted gene co-expression network (WGCNA),...
ABSTRACT Background High‐intensity focused ultrasound (HIFU) is a promising minimally invasive treatment for liver cancer; however, its efficacy often limited by the attenuation of ultrasonic energy. This study investigates effectiveness B7‐H3‐targeted microbubbles (T‐MBs) in enhancing HIFU ablation cancer and explores their potential clinical translation. Methods T‐MBs isotype control (I‐MBs) were synthesized through conjugation biotinylated anti‐B7‐H3 antibody to microbubble surface,...
Background: Ovarian cancer presents a substantial risk to women's health and lives, with early detection treatment proving challenging. Targeted nanodelivery systems are viewed as promising approach enhance the effectiveness of ovarian ultrasonic imaging outcomes. Objective: A phase-shifted system (NPs) loaded paclitaxel (PTX) further conjugated avidin (Ab) was studied, goal investigating effects targeted strategies on in vitro therapeutic efficacy cancer. This study provides foundation for...
The task allocation process in the Witkey mode is dynamic and open, which a rational person. Due to Witkey's individual rationality, order make result of stable, must reach Nash equilibrium. However, equilibrium point does not necessarily have highest total system revenue. In stable high revenue, this paper proposes an incentive measure based on integral ranking improve user participation. When adopts best response strategy select task, participating selection will affect income certain...
Objective To investigate the effect of Shenfu injection on expressions endoplasmic reticulum stress-related factors oxygen-regulated protein 150 (ORP150), X-box binding 1(XBP1), and C/EBP homologous (CHOP) mRNAs in cerebral cortical neurons after hypoxic-ischemic brain damage (HIBD) neonatal rats. Methods The 7 day-newborn Sprague-Dawley rats were randomly divided into sham operation, normal saline treatment (Shenfu injection, 10ml/kg per day, peritoneal for 3 days) groups. They...
This paper explores the application of a new algebraic method color exchanges to edge coloring simple graphs. Vizing's theorem states that graph $G$ requires either $Δ$ or $Δ+1$ colors, where is maximum vertex degree $G$. Holyer proved it {\bf NP}-complete decide whether $Δ$-edge-colorable even for cubic By introducing concept complex we show color-exchange operation follows same multiplication rules as quaternion. An initially $Δ$-edge-colored allows variable-colored edges, which can be...
Abstract Background: This study aimed to investigate the prognostic risk factors of T2-T4 thoracic esophageal cancer and survival benefit common treatment modalities provide a basis for selecting most appropriate treatment. Methods: population-based retrospective cohort collected data patients diagnosed with between 2010 2016 in Surveillance, Epidemiology, End Results database. Patients were divided according those who had surgery radiotherapy. Survival curves generated using Kaplan–Meier...
We present deep learning-based virtual immunohistochemical (IHC) HER2 staining of label-free breast tissue sections, matching the standard IHC performed by histotechnologists. © 2022 The Author(s)
In practical applications, there are many task allocation problems involving the participation of self-interested agents, including Witkey, crowdsourcing and electronic markets. these cases, to improve efficiency allocation, a reasonable distribution utilities is critical. To best our knowledge, few studies have examined complex utility good solutions lacking. address this issue, following works done in paper: first, based on model for agents by studying Nash bargaining solution...