A5036306134- Neonatal Respiratory Health Research
- Craniofacial Disorders and Treatments
- Cleft Lip and Palate Research
- Birth, Development, and Health
- Cancer Genomics and Diagnostics
- Lung Cancer Treatments and Mutations
- Assisted Reproductive Technology and Twin Pregnancy
- RNA Research and Splicing
- Lung Cancer Research Studies
- Fetal and Pediatric Neurological Disorders
- Infant Nutrition and Health
- Congenital Diaphragmatic Hernia Studies
- Cancer Cells and Metastasis
- Total Knee Arthroplasty Outcomes
- Wnt/β-catenin signaling in development and cancer
- IgG4-Related and Inflammatory Diseases
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Acute Myocardial Infarction Research
- Inflammasome and immune disorders
- Tuberculosis Research and Epidemiology
- Growth Hormone and Insulin-like Growth Factors
- Streptococcal Infections and Treatments
- Ethics and Legal Issues in Pediatric Healthcare
- Breastfeeding Practices and Influences
- Mycobacterium research and diagnosis
Nanjing Medical University
2024
Kangda College of Nanjing Medical University
2024
Jiaxing University
2019-2024
Peking University
2015-2023
Peking University Third Hospital
2015-2023
Second People’s Hospital of Huai’an
2020-2022
Xuzhou Medical College
2020-2022
Children's Hospital of Zhejiang University
2019-2022
Second Affiliated Hospital of Zhejiang University
2020
Beijing Sanbo Brain Hospital
2017
Background: Cholestatic liver diseases induce local and systemic hypercoagulation, with neutrophil extracellular traps (NETs) serving as major drivers. These NETs have been linked to decreased function in patients obstructive jaundice. However, the impact of on hypercoagulation cholestatic disease remains unknown. Methods: We utilized bile duct ligation create experimental mice analyzed formation liver. Fibrin deposition, tissue factor expression, inflammation were visualized through western...
Tumour-infiltrating immune cells have been indicated to play an important role in prognosis prediction and therapy sensitivity for breast cancer. In recent years, estimating the abundance of based on tumour transcriptome data has provided a novel way analyse clinical significance various cell subsets. This study integrated cancer tissue datasets from Gene Expression Omnibus (GEO), Cancer Genome Atlas-Breast (TCGA-BRCA) Molecular Taxonomy Breast International Consortium (METABRIC) cohorts. A...
Human discs large-associated protein 5 (DLGAP5), a microtubule-associated protein, has been reported to be upregulated in several tumors. However, the role of DLGAP5 endometrial cancer (EC) progression and related underlying mechanism were still unknown. A bioinformatics analysis was performed analyze expression prognostic significance EC tissues using TCGA, CPTAC, Protein Atlas, GSE63678 databases, UALCAN web tool, Kaplan-Meier plotter. Effects DLGAP on cell malignant properties evaluated...
Background: For children with catastrophic epilepsy, vagus nerve stimulation has been demonstrated as a palliative treatment for those surgical contraindication. The purpose of our study was to assess the efficacy on seizures, neuropsychological in children. Methods: Our reviewed files 56 treated between May, 2008 and December, 2013 center. Data collected from baseline 12, 24 months follow-up, including seizure frequency, duration, severity outcomes. Results: In population these children,...
Epidermal growth factor receptor (EGFR) exon 20 insertion mutations are uncommon EGFR and generally resistant to first- second-generation EGFR-tyrosine kinase inhibitors (TKIs). In precision oncology, treatment regimens tested for improving the clinical outcomes. Zebrafish embryo tumor transplant models used in cancer research.We report two Chinese females who were diagnosed with stage IV lung adenocarcinoma shown harbor by next-generation sequencing (NGS). Then, we established...
Whether or not EGFR mutation status detected by ddPCR in plasma predicts the effect of icotinib on patients with advanced lung adenocarcinoma was determined.Plasma and matched tissue specimens from were collected prior to treatment. The ARMS method used detect DNA extracted specimens, while ctDNA determined ddPCR. therapeutic effects compared between EGFR-activating mutations DNA.EGFR 96 100 specimens. sensitivity positive predictive value 19del 70.97% (22/31) 44.90% (22/49), respectively....
Objective: To discuss the relationship between breastfeeding and behavioral development of infants children. Methods: Based on Ma'anshan Birth Cohort Study, there were 3 474 pregnant women recruited from Maternal Child Care Center May 2013 September 2014, including 273 singleton live births. Follow up to age 18 months old. Excluded with incomplete information who did not finish ASQ-3 evaluation in 6 old old, 2 404 valid subjects included study. The demographic characteristics, deliver, was...
Understanding metabolite profiles may aid in providing a reference for individualized treatment using PEG-rhGH. Therefore, this study aimed to evaluate the clinical efficacy of PEG-rhGH treating GHD patients by metabolomic approach. Fifty-seven pediatric participants treated with were enrolled (28 high and 29 lower efficacy). Serum samples from all first collected at baseline biochemical detection; then levels measured gas chromatography time-of-flight mass spectrometry. The candidates...
To the Editor: Drug-induced immune hemolytic anemia (DIIHA) is a rare but severe condition. Ceftriaxone, third-generation cephalosporin with wide antibacterial spectrum and effective action, one of most common drugs causing DIIHA.[1] Ceftriaxone-induced (CIIHA) potentially fatal complication.[2] Most patients were children. The reported fatality rate CIIHA was as high 40%.[3] Acute renal failure cardiovascular decompensation are lethal complications in pediatric CIIHA.[2] Early diagnosis...
In monozygotic monochorionic diamnionic twin pregnancy, twin-twin transfusion syndrome is one of the most serious complications and often exhibit growth not well proportioned, abnormal amniotic fluid volume other complications.Twin anemia-polycythemia sequence a special type Twin-twin syndrome, both have great difference in clinical manifestations, diagnosis prognosis neonatal stages.This article compares with pathogenesis, diagnostic criteria, treatment methods these two diseases. Key...
Acute pulmonary embolism (APE) is a serious complication after off-pump coronary artery bypass grafting (OPCABG). We aimed to analyze the risk factors for APE in patients with OPCABG. In this retrospective, observational study, OPCABG who were treated our hospital from 1 January 2018 31 March 2020 included. The basic characteristics of and results preoperative laboratory examinations collected analyzed. A total 707 included incidence was 3.21%. Left ventricular ejection fraction (LVEF),...
To study the effects of infantile positional plagiocephaly on growth and neural development.A retrospective was conducted medical data 467 children who underwent craniographic examination were followed up to 3 years age in Peking University Third Hospital from June 2018 May 2022. They divided into four groups: mild (n=108), moderate (n=49), severe (n=12), normal cranial shape (n=298). The general information groups weight, length, head circumference, visual acuity screening results, hearing...
Objective: To investigate the knowledge regarding clinical research among children at 8-18 years of age. The survey results will form basis for developing public education program this population. Methods: was conducted age using WeChat and spot investigation between January 2016 2017. According to different developmental stages, population divided into four groups: 8-10, 11-13, 14-15 16-18 years. level analyzed. Results: Totally 1 329 questionnaires were issued 233 effective returned with a...