Hongkui Chen

ORCID: 0000-0003-3124-772X
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About
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Research Areas
  • Cancer Research and Treatments
  • Immunotherapy and Immune Responses
  • Cancer, Hypoxia, and Metabolism
  • RNA Interference and Gene Delivery
  • Immune Cell Function and Interaction

Macau University of Science and Technology
2025

Background: In cancer immunotherapy, gene therapy has become a promising strategy through the introduction of immunostimulatory components into its formulation. However, ideal non-viral delivery platforms capable simultaneously maintaining high efficiency and immune activation are still in demand. As an intestinal probiotic, Lactobacillus reuteri potential correlation with progression. Its unique antigenicity also confers immunomodulatory activity. Method: We engineered new siRNA system,...

10.3390/pharmaceutics17020139 article EN cc-by Pharmaceutics 2025-01-21
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