A5029142475- Synthesis and Characterization of Heterocyclic Compounds
- Synthesis and Biological Evaluation
- Chemical Reaction Mechanisms
- Synthesis and Reactions of Organic Compounds
- Synthesis and Reactivity of Sulfur-Containing Compounds
- Synthesis and biological activity
- Advanced Memory and Neural Computing
- Multiferroics and related materials
- Magnetic and transport properties of perovskites and related materials
- Monoclonal and Polyclonal Antibodies Research
- Synthesis and Reactivity of Heterocycles
- CCD and CMOS Imaging Sensors
- Ferroelectric and Negative Capacitance Devices
- Synthesis of heterocyclic compounds
- Protein purification and stability
- Mobile Agent-Based Network Management
- Advanced Condensed Matter Physics
- Glycosylation and Glycoproteins Research
- Quinazolinone synthesis and applications
- Chemical Synthesis and Analysis
- Multi-Agent Systems and Negotiation
- DNA and Nucleic Acid Chemistry
- Advancements in Semiconductor Devices and Circuit Design
- Peer-to-Peer Network Technologies
- Organophosphorus compounds synthesis
Georgia Institute of Technology
2023-2025
Asahi Kasei (Japan)
2020-2025
Tohoku University
2004-2020
Hatch (Canada)
2014
Graduate School USA
2014
Chiba Institute of Technology
2002
University of Georgia
1978
Vision-based high-speed target-identification and tracking is a critical application in unmanned aerial vehicles (UAV) with wide military commercial usage. Traditional frame cameras processed through convolutional neural networks (CNN) exhibit high accuracy but low throughput (hence speed) power. On the other hand, event or dynamic vision sensors (DVS) generate stream of binary asynchronous events corresponding to changing intensity pixels capturing temporal information, characteristic...
This letter describes a Delta-Sigma ADC based Power-Side-Channel-Attack Sensor. Use of 64 sampling capacitors allows the use over-sampling architecture even with decoupling capacitor connected to power supply. The LDO low-leakage S/H is used as driver for integrator's amplifier minimize offset error. A differential conversion method utilizing Dual-Integrate (CAPs) provides signal processing compensate drift due supply voltage (VDD) variations. prototype sensor chip fabricated in 65nm CMOS...
Fc domain fusion can improve the therapeutic effects of relatively small biological molecules such as peptides, cytokines, and antibody fragments. proteins also be used to enhance cytotoxic bispecific antibodies (bsAbs). However, fragmentation proteins, which mainly occurs around hinge regions during production, storage, circulation in blood, is a major issue. In this study, we first investigated mechanisms region storage using Fc-fused bsAbs with specificity for epidermal growth factor...
One approach to creating more beneficial therapeutic antibodies is develop bispecific (bsAbs), particularly IgG-like formats with tetravalency, which may provide several advantages such as multivalent binding each target antigen. Although the effects of configuration and antibody-fragment type on function bsAbs have been studied, there only a few detailed studies influence variable fragment domain order. Here, we prepared four types hEx3-scDb-Fc, bsAbs, built from single-chain hEx3-Db...
Accurate identification of the target and tracking it at high speeds using drone-mounted cameras compute hardware finds military commercial applications. Conventional frame-based convolutional neural networks (CNNs) extract detailed spatial information to show accuracy but suffer from lower throughput caused by large models. Alternatively, event capture motion as an asynchronous stream with temporal resolution. Spiking (SNNs) can be used process these data speed, sparse sensing difficulty in...
A dense compute-in-memory (CIM) macro using resistive random-access memory (RRAM) showing solutions to read channel mismatch, high I <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">OFF</inf> , ADC offset, IR drop, and cell resistance variation is presented. By combining a hybrid analog/mixed-signal offset cancellation scheme $I_{CELL}R_{BLSL}$ drop mitigation with low bias target voltage, the proposed demonstrates robust operation (post-ECC bit...
We have been working on research and development of advanced network applications called "flexible computing". are now in the next stage this research, strongly pressing forward concept flexible computing, namely, "symbiotic computing", towards generation computing model based co-existence real space digital space. In paper, we explain basic concepts, architecture enabling technologies symbiotic that aiming to develop.
We demonstrate the chip-based 3D heterogeneous integration technology for realizing highly parallel 3D-stacked image sensor. Three kinds of chips, CMOS sensor chip, analog circuit and ADC array which were fabricated by different technologies, are processed stacked vertically to form a prototype Through-Si vias (TSVs) metal micro-bumps formed in chip-level before stacking. The fundamental characteristics evaluated
Countermeasures against power side-channel attack (SCA) range from algorithmic modifications to modifying the consumption characteristics of device by inclusion noise sources or suppressing current signature. However, these techniques are, in most cases, passive protection and come with unacceptable area overheads for resource-constrained devices. In this letter, we propose a SCA detection sensor based on 1-b delta-sigma analog-to-digital converter, which allows an ongoing within as fast...
Generally, in order to manage and maintain a network system, it is necessary carry out series of operations including assessing the status, determining errors, selecting/approving countermeasures applying countermeasures. Since systems are becoming more complicated larger scale, increasingly require special professional knowledge effort, thereby imposing heavy workloads on administrators. In this paper, we propose design AIR-NMS (Active Information Resource Architecture based Network...
Measurements of magnetization, electrical resistivity, and synchrotron x-ray diffraction were performed on single crystals ${\mathrm{Bi}}_{1\ensuremath{-}x}{\mathrm{Sr}}_{x}\mathrm{Mn}{\mathrm{O}}_{3}$ $(0.35\ensuremath{\leqslant}x\ensuremath{\leqslant}0.64)$. The resistivity magnetization curves show a kink near $570\phantom{\rule{0.3em}{0ex}}\mathrm{K}$ an anomaly which is accompanied by hysteresis at $400--500\phantom{\rule{0.3em}{0ex}}\mathrm{K}$ for all samples. Synchrotron sample with...
This letter describes an analog current-summing compute-in-memory macro using resistive random-access memory (RRAM). The readout transimpedance amplifiers use offset cancelling with differential inputs from added sensing paths for the bitline (BL) and sourceline (SL) to minimize channel-to-channel (ch./ch.) gain error while mitigating IR drop in BL, SL, multiplexors (MUXes). analog-to-digital converters (ADCs) dynamic cancellation remove ch./ch. ADC intrinsic due RRAM off-state current. 64Kb...
This paper presents a THD improved SAR ADC without any calibration or DEM for DAC mismatch. The proposed has new method of cancellation all even order distortions caused by In to improve performance, we focused on symmetric property in the just needs very simple circuits with few extra clocks.
Domain switching in the charge/orbital-ordered state of ${\text{La}}_{0.5}{\text{Sr}}_{1.5}{\text{MnO}}_{4}$, which can be manipulated by applying an electric field, was studied situ transmission electron microscopy. Dark-field images revealed formation micrometer-scale domains on cooling, were separated a clearly defined, meandering interface. Applying uniaxial field aided growth domain with its orbital chain (i.e., direction easy hopping) parallel to applied field. These observations...
Abstract Das Triazin (I) reagiert mit den metallorganischen Verbindungen (II) zu Dihydrotriazinen (III), die K 3 Fe(CN) 6 oder KMnO 4 5‐Aryltriazinen (IV) oxidiert werden.
Abstract Designing non-natural antibody formats is a practical method for developing highly functional next-generation drugs, particularly improving the therapeutic efficacy of cancer treatments. One approach constructing bispecific antibodies (bsAbs). We previously reported humanized diabody (bsDb) that targeted epidermal growth factor receptor and CD3 (hEx3-Db). enhanced its cytotoxicity by an Fc fusion protein rearranging order V domain. In this study, we created additional bsAb,...
The electric perturbation effect to the charge-orbital ordering state has been investigated for Bi1−xSrxMnO3 (x∼0.5). alignment and rotation of stripes have observed in resistance polarizing microscope images at room temperature. These results indicate possibility electrical control anisotropic properties through orbital degree freedom.
We have investigated the electric field effect on domain structure with respect to orbital-stripe direction in charge–orbital-ordered (COO) state of layered manganite La1/2Sr3/2MnO4. A fine 90° is observed using a polarizing microscope. After application electrical current melt COO domains by Joule heating and following gradual decrease current, one kind becomes predominant. Synchrotron X-ray diffraction analysis confirms that orbital stripes tend extend parallel direction.
A highly dependable 3-D stacked multicore processor module composed of 4-layer chip and 2-layer cache memory is implemented using reconfigured multichip-on-wafer integration backside TSV technologies for the first time. Tier boundary scan, self-repair circuits, BIST circuits in basic read/write functions are successfully evaluated. High-density TSVs micro-joining characteristics were evaluated by a non-destructive method high resolution X-ray CT scanning tool.