- Catalytic Processes in Materials Science
- Catalysis and Oxidation Reactions
- ZnO doping and properties
- Gas Sensing Nanomaterials and Sensors
- Advanced Photocatalysis Techniques
- Copper-based nanomaterials and applications
- Graphene research and applications
- Nanocluster Synthesis and Applications
- Advanced biosensing and bioanalysis techniques
- Receptor Mechanisms and Signaling
- Nanomaterials for catalytic reactions
- Ammonia Synthesis and Nitrogen Reduction
- Quantum Dots Synthesis And Properties
- Advanced Chemical Physics Studies
- X-ray Diffraction in Crystallography
- Hydrogels: synthesis, properties, applications
- Nanoparticle-Based Drug Delivery
- Analytical chemistry methods development
- Inorganic Chemistry and Materials
- Pesticide Residue Analysis and Safety
- Boron and Carbon Nanomaterials Research
- Molecular Sensors and Ion Detection
- Ga2O3 and related materials
- Autophagy in Disease and Therapy
- Electrochemical Analysis and Applications
Shenyang University of Chemical Technology
2023-2025
Zhangjiakou Academy of Agricultural Sciences
2021-2025
Inner Mongolia University of Science and Technology
2025
Jiangsu University
2024-2025
First People's Hospital of Chongqing
2024
Hubei University of Chinese Medicine
2020-2024
Chongqing Public Health Medical Center
2024
Chongqing Medical University
2024
Yuhuangding Hospital
2019-2024
Chinese Academy of Sciences
2017-2023
Abstract Objective Hepatocellular carcinima is one of the most common tumors in clinic and also leading causes death from cancer worldwide. Quercetin shows significant effects on blocking development various cancers. Methods We used human hepatocellular carcinoma LM3 nude mice tumor model to assess quercetin clarify its mechanism action. collected cell line treated with different doses at time periods determined vital indexes. The liver tissues were for western boltting (WB), Hematoxylin...
Cleavage of the triple N≡N bond by metal clusters is fundamental interest and practical importance in nitrogen fixation. Previous studies cleavage gas-phase emphasized dinuclear centers. Herein, dissociative adsorption N2 subsequent C-N coupling on trinuclear carbide cluster anions V3C4- under thermal collision conditions have been characterized employing mass spectrometry (collision induced dissociation), cryogenic photoelectron imaging spectroscopy, quantum chemistry calculations. A...
Shikonin is a natural product with many activities, including anti-cancer effects. Pyruvate kinase type M2 (PKM2) plays crucial role in the growth of tumor cells. However, effect shikonin on PKM2 hepatocellular carcinoma (HCC) unclear.Cell viability, apoptosis level, glucose uptake, and lactate production were detected HCC Lentivirus-overexpressed -shRNA used to verify key target shikonin. A xenograft mouse model was detect efficacy its combination sorafenib vivo.Shikonin inhibited...
Oxide supported gold catalysts (e.g., Au/TiO2) are of great significance in heterogeneous catalysis owing to their extraordinary catalytic activity. Study heteronuclear metal oxide clusters (HMOCs, e.g., AuxTiyOzq) is an important way uncover the molecular-level mechanisms related systems. However, current studies HMOCs focused on charged with little attention paid neutral species. The reactivity study vital have a comprehensive understanding catalysis, but it experimentally challenging...
Hepatic ischemia reperfusion (IR) injury (IRI) occurs during liver transplantation, hepatectomy, and hemorrhagic shock. Oleanolic acid (OA) is a natural compound with antioxidant anti-inflammatory activity that has been used to treat disorders in clinical practice for several years. Here, we investigated the effects underlying mechanisms of OA hepatic IRI. A 60-minute partial (70%) hepatic, warm, ischemic model was established BALB/c mice, two doses (30 60 mg/kg) were administered...
The electronic structure of two-dimensional (2D) materials in van der Waals heterojunctions also appears extensive theoretical research, we use DFT-D2 theory to calculate the energy band, density states, formation energy, work function, charge difference, optical properties, and our calculations show that there is no electrons holes redistribution at intrinsic ZnO composite graphene interface, vacancy defects doping not only make electron–hole good separation, but a significant increase UV...
Catalytic conversion of toxic nitrogen oxide (NO) and carbon monoxide (CO) into (N2) dioxide (CO2) is imperative under the weight increasingly stringent emission regulations, while a fundamental understanding nature active site to selectively drive N2 generation elusive. Herein, in combination with state-of-the-art mass-spectrometric experiments quantum-chemical calculations, we demonstrated that rhodium-cerium clusters RhCe2O3-5- can catalytically NO reduction by CO give rise CO2. This...
Salvianolic acid A (SAA), an important bioactive polyphenolic found in Salvia miltiorrhiza Bunge, may be used for treating metabolic disorders due to its anti-inflammatory activity. Since chronic inflammation plays role type 2 diabetes mellitus (T2DM) complicated with atherosclerosis (AS), SAA have beneficial effects on AS. Here, we evaluated the of male Zucker diabetic fatty (ZDF) rats induced by a high-fat diet and Vitamin D3 injections. Compared model group, high dosage (1 mg/kg) group...
Aflatoxin B1 (AFB1) is highly toxic and challenging to remove, posing significant risks both human health economic development. Therefore, there an urgent need develop rapid, simple, sensitive detection technologies. In this study, we introduce a naked-eye colorimetric method based on multiple isothermal amplifications coupled with CRISPR–Cas14a investigate its biosensing properties. This technique utilizes composite nanoprobes (MAPs) comprising magnetic nanoparticles gold nanoparticles....
Recently, interest in stimuli-responsive core–shell nanogels as drug delivery systems for tumor therapy has increased.
Pectate lyase (PL) holds significant potential for applications in various industries. However, the existing PL was unable to adapt thermo-alkaline industrial environments. In this work, a from Caldicellulosiruptor bescii DSM 6725 (hereafter, CbPelD) studied disclose its structural and biochemical properties. CbPelD consisted of putative signal peptide sequence, short linker region, catalytic domain (PelD-II), along with an exoacting β-fructofuranosidase (PelD-I). molecular dynamics...