A5062226287- Granular flow and fluidized beds
- Drug Solubulity and Delivery Systems
- Mineral Processing and Grinding
- Injection Molding Process and Properties
- Powder Metallurgy Techniques and Materials
- Protein purification and stability
- Advanced Data Compression Techniques
- Ultrasonics and Acoustic Wave Propagation
- Additive Manufacturing and 3D Printing Technologies
- Fluid Dynamics and Heat Transfer
- Crystallization and Solubility Studies
- Water Systems and Optimization
- VLSI and FPGA Design Techniques
- Drilling and Well Engineering
- Power Line Communications and Noise
- Non-Destructive Testing Techniques
- Dental Radiography and Imaging
- Fluid Dynamics and Mixing
- Dental Research and COVID-19
University of Strathclyde
2017-2024
Engineering and Physical Sciences Research Council
2017-2022
It is important during powder granulation to obtain particles of a homogeneous size especially in critical situations such as pharmaceutical manufacture. To date, homogeneity particle distribution has been defined by the use d50 combined with span distribution, which found ineffective for polymodal distributions. This work focuses on demonstrating limitations parameter quantify and proposes novel improved metric based transformation typical curve into factor can vary from 0 100%. The...
Recent years have seen the advent of Quality-by-Design (QbD) as a philosophy to ensure quality, safety, and efficiency pharmaceutical production. The key processing methodology Direct Compression produce tablets is also focus some research. traditional Design-of-Experiments purely experimental approach achieve such quality process development goals can significant time resource requirements. present work evaluates potential for using combined modelling approach, which may reduce this burden...
Continuous Direct Compaction (CDC) has emerged as a promising route towards producing solid dosage forms while reducing material, development time and energy consumption. Understanding the response of powder processing unit operations, especially blenders, is crucial. There substantial body work around how lubrication via batch blender operation affects tablet critical quality attributes such hardness tensile strength. But, aside from being design these blenders that they operate with...
With the emergence of quality by design (QbD), it becomes imperative to gain understanding impact batch-to-batch variability raw materials on performance processes. Feeding is first unit operation in a continuous manufacturing line and critical for final product quality. The feeders defines content components that are fed into system therefore composition ends up formulation. In this paper, investigated how what extent lactose can feeding different feeder set-ups. Spray dried SuperTab 11SD...
Abstract Cracks in dents or linear anomalies interacting with are a major pipeline threat. These combined represent challenges to the Mechanical Engineers that design ILI tools as they need keep sensor an optimal position towards inner pipe wall. Ultrasonic Crack (UC) consist plate fixed incidence angle depends on coupling medium. This is then attached skids; these constant contact internal When tool interacts dent, not optimal; therefore, detection of any feature compromised. By having...