A5000818078- Neonatal Respiratory Health Research
- Pregnancy and preeclampsia studies
- Birth, Development, and Health
- Healthcare Systems and Practices
- Maternal and Perinatal Health Interventions
- Health, Medicine and Society
- Infant Development and Preterm Care
- Global Maternal and Child Health
- Neonatal and fetal brain pathology
- Bone health and osteoporosis research
- Maternal and fetal healthcare
- Gestational Diabetes Research and Management
- Assisted Reproductive Technology and Twin Pregnancy
- Child and Adolescent Health
- Preterm Birth and Chorioamnionitis
- Pediatric Urology and Nephrology Studies
- Hip and Femur Fractures
- Neuroscience of respiration and sleep
- Urinary Tract Infections Management
- Pregnancy-related medical research
- Cardiovascular Issues in Pregnancy
- Pregnancy and Medication Impact
- Menopause: Health Impacts and Treatments
- Pneumonia and Respiratory Infections
- Endometriosis Research and Treatment
Académie Nationale de Médecine
2013-2024
Inserm
2010-2020
Sorbonne Université
2008-2020
Centre de Recherche Épidémiologie et Statistique
2015-2020
Université Paris Cité
1973-2020
Hôpital Tenon
2004-2020
Société Française de Médecine Vasculaire
2020
Maternité Port Royal
1989-2018
Sorbonne Paris Cité
2015-2018
Gouvernance, Risque, Environnement, Développement
2017
Background. Existing fetal growth references all suffer from 1 or more major methodologic problems, including errors in reported gestational age, biologically implausible birth weight for insufficient sample sizes at low single-hospital other non-population–based samples, and inadequate statistical modeling techniques. Methods. We used the newly developed Canadian national linked file of singleton births infant deaths between 1994 1996, which age is largely based on early ultrasound...
Abstract Increased bone turnover has been suggested as a potential risk factor for osteoporotic fractures. We investigated this hypothesis in prospective cohort study performed on 7598 healthy women more than 75 years of age. One hundred and twenty-six (mean 82.5) who sustained hip fracture during mean 22-month follow-up were age-matched with three controls did not fracture. Baseline samples collected prior to the measurement two markers formation urinary resorption: type I collagen...
In Brief OBJECTIVE: A continuous rise in the rate of cesarean delivery has been reported many countries during past decades. This trend prompted emergence a controversial debate on risks and benefits associated with delivery. Our objective was to provide valid estimate risk postpartum maternal death directly as compared vaginal METHODS: population-based case–control study designed, subjects selected from recent nationwide surveys France. To control for indication bias, deaths due antenatal...
Increased levels of circulating undercarboxylated osteocalcin (ucOC), measured indirectly with the hydroxyapatite (HAP) binding assay, have been shown to predict hip fracture risk in a small group elderly institutionalized women. The aim this study was confirm these findings prospective cohort (EPIDOS study) 7598 healthy, independently living women over 75 yr age. One hundred and four who sustained during 22-month follow-up period were age matched 255 controls did not fracture. Baseline...
OBJECTIVE. To estimate the prevalence of cerebral palsy at 2 years age among children born very preterm, according to gestational age, infant gender, plurality, and neonatal cranial ultrasound abnormalities. METHODS. All infants between 22 32 weeks gestation in 9 regions France 1997 were included this prospective, population-based, cohort study. The main outcome measure was years. Of 2364 survivors eligible for follow-up evaluation, 1954 (83%) assessed age. RESULTS. Among years, 8.2% had...
Abstract Fracture of the proximal humerus is one most frequent fractures attributable to osteoporosis; yet, it has seldom been studied. Two types factors (related bone fragility and falls) were evaluated identify risk for as well examine possible interactions between them. Subjects 6901 white women aged ≥75 years all participated in EPIDOS study osteoporotic (France, 1992-1998). The baseline examination included measurements femoral neck mineral density (BMD) calcaneal ultrasound parameters...
Objectives: To assess whether the occurrence of a hip fracture is associated with an increased risk mortality even after taking into account age and prefracture health status this persists beyond first 6 months fracture. Design: A prospective study factors for Setting: Five French areas: Amiens, Lyon, Montpellier, Paris, Toulouse. Participants: The cohort consisted 7,512 volunteer ambulatory women aged 75 older who were recruited from voter registration lists. Women had history or bilateral...
Aim The aim of this study was to assess the independent role cerebral lesions on ultrasound scan, and several other neonatal obstetric factors, as potential predictors palsy (CP) in a large population‐based cohort very preterm infants. Method As part EPIPAGE, prospective study, perinatal data outcome at 5 years age were recorded for 1812 infants born before 33 weeks gestation nine regions France 1997. Results group comprised 942 males (52%) 870 females with mean gestational 30 (SD 2wks;...
In Brief OBJECTIVE: Available maternal mortality statistics do not allow valid international comparisons. Our objective was to uniformly measure underreporting of from pregnancy in official selected regions within the U.S. and Europe, provide comparable revised profiles pregnancy-related mortality. METHODS: We developed a standardized enhanced method identify classify pregnancy-associated deaths 2 states, Massachusetts North Carolina, European countries, Finland France, for years 1999–2000....
OBJECTIVE. We sought to (1) evaluate at 2 years the postsurfactant era developmental outcome of children who were born before 33 weeks gestational age (GA) in Nord-Pas-de-Calais area France 1997 and (2) identify risk factors poor quotient (DQ). Children part EPIPAGE study, which included all these births 9 French regions. METHODS. A prospective observational study was conducted 1997. Risk DQ obtained from a multiple linear regression, results expressed as differences with 95% confidence...
In Brief OBJECTIVE: To estimate quality of life, prevalence, and risk factors associated with symptomatic pelvic organ prolapse (POP) among middle-aged women. METHODS: This was a cross-sectional study. A questionnaire mailed to 3,114 women aged 50–61 years in the GAZEL cohort; 2,640 (85%) returned it. Symptomatic POP defined by feeling bulge from vagina (sometimes, often, or all time compared never rarely). Quality life determined Nottingham Health Profile questionnaire. Multiple linear...
OBJECTIVES. Advances in perinatal medicine increased survival after very preterm birth all countries, but comparative population-based data on these births are not readily available. This analysis contrasts the rates and short-term outcome of live before 32 weeks gestation 10 European regions. METHODS. The Models Organizing Access to Intensive Care for Very Preterm Births (MOSAIC) study collected prospective regions covering 494463 total 2003. sample was between 24 31 without lethal...
In Brief OBJECTIVE: To evaluate the rates of in-hospital death, neonatal complications, and 5-year outcomes infants born at 30–34 weeks gestation. METHODS: nine regions France, all 2,020 stillbirths live births 30, 31, 32 in 1997 457 33 34 April October were recorded. Survivors evaluated 5 years age. RESULTS: Increasing gestational age from 30 to was associated with progressive decreases mortality (from 8.1% 0.4%) complications (respiratory distress syndrome, 43.8% 2.6%; maternofetal...