A5042106313- Pneumothorax, Barotrauma, Emphysema
- Pleural and Pulmonary Diseases
- Trauma Management and Diagnosis
- Lung Cancer Treatments and Mutations
- Urinary Bladder and Prostate Research
- Tracheal and airway disorders
- Medical Imaging and Pathology Studies
- Lung Cancer Diagnosis and Treatment
- Bladder and Urothelial Cancer Treatments
- Genomics and Chromatin Dynamics
- Aldose Reductase and Taurine
- Teratomas and Epidermoid Cysts
- Cancer, Stress, Anesthesia, and Immune Response
- Sexual function and dysfunction studies
- Radiomics and Machine Learning in Medical Imaging
- Head and Neck Surgical Oncology
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Advanced Glycation End Products research
- Myasthenia Gravis and Thymoma
- Urologic and reproductive health conditions
- RNA Research and Splicing
- Nuclear Structure and Function
- Urinary Tract Infections Management
- Pituitary Gland Disorders and Treatments
- Urinary and Genital Oncology Studies
Kyoto University Hospital
2023-2025
Japanese Red Cross Society Wakayama Medical Center
2024-2025
Fukui Prefectural Hospital
2025
Komatsu (Japan)
2024
University of Fukui
2024
Kobe City Medical Center General Hospital
2020-2023
Kobe City Nishi-Kobe Medical Center
2023
Kyoto University
2020
Nagahama City Hospital
2020
Neoadjuvant, adjuvant, and perioperative immune checkpoint inhibitor (ICI) regimens for treating locally advanced lung cancer have dramatically evolved in recent years. Despite these immunotherapies being very promising, they can be associated with potential life-threatening immune-related adverse events (irAEs), there is not much awareness regarding irAEs surgical regimens. A Japanese man his 70s was diagnosed right upper lobe adenocarcinoma (cT3N1[#12u]M0, parietal pleural invasion, cStage...
We aimed to elucidate the efficacy of conventional cisplatin-based adjuvant chemotherapy for patients with lung cancers harboring epidermal growth factor receptor (EGFR) mutation. This retrospective cohort study included 110 (EGFR mutation group: n = 51; EGFR wild-type 59) receiving following complete resection non-small-cell non-squamous-cell cancer (2010-2021). Clinicopathological characteristics, recurrence-free survival (RFS), and overall (OS) were investigated. The pStage distribution...
ABSTRACT Introduction Lobular capillary hemangioma is a benign tumor that commonly occurs in the skin and mucous membranes. A lobular within blood vessels called intravenous hemangioma. In this report, we report fifth case of originating from renal vessel. Case Presentation 68‐year‐old man was diagnosed with right cell carcinoma vein thrombus on computed tomography examination for asymptomatic aortic valve stenosis. The patient underwent robot‐assisted laparoscopic radical nephrectomy...
Primary spontaneous pneumothorax occasionally relapses, even after bullectomy; therefore, coverage of the bullectomy staple line for pleural reinforcement is common in Japan. However, appropriate covering materials have not yet been determined.This was a longitudinal prospective cohort study. Data were available patients aged < 40 years with primary who underwent their first thoracoscopic between July 2015 and June 2021. We used oxidized regenerated cellulose (ORC) sheets from to 2018,...
Abstract Background It has been recently recognized that pulmonary cyst may develop after resection, causing various symptoms. Most previously reported cases were upper lobectomy in patients with chronic obstructive lung disease (COPD). Case presentation 1 was a man his 70 s interstitial pneumonia (IP). Right lower performed for metastatic tumor using video-assisted thoracoscopic surgery (VATS). On postoperative day (POD) 19, computed tomography (CT) revealed large at the interlobular...
Abstract SRSF4 is one of the members serine‐/arginine (SR)‐rich protein family involved in both constitutive and alternative splicing. localized nucleus with speckled pattern, but its nuclear localization signal was not determined. Here, we have identified signals (NLSs) by using a pyruvate kinase fusion system. As expected, arginine‐/serine (RS)‐rich domain confers activity when it fused to PK protein. We then further delineated minimum sequences for RS SRSF4. Surprisingly, RS‐rich region...
Barotrauma frequently occurs in coronavirus disease 2019. Previous studies have reported barotrauma to be a mortality-risk factor; however, its time-dependent nature and pathophysiology are not elucidated. To investigate the characteristics etiology of 2019-related-barotrauma.We retrospectively reviewed intubated patients with 2019 from March 2020 May 2021. We compared 90-day survival between non-barotrauma groups performed landmark analyses on days 7, 14, 21, 28. within seven before was...
ABSTRACT Purpose The bladder dysfunction associated with type 2 diabetes mellitus (T2DM) involves urine storage and voiding disorders. We evaluated the pathologic conditions of wall in a rat model T2DM effects phosphodiesterase-5 (PDE-5) inhibitor tadalafil (TA). Materials Methods Male Otsuka Long-Evans Tokushima Fatty (OLETF) rats (LETO) comprised control groups. TA was orally administered for 12 weeks. blood flow ATP released from epithelium were measured using laser speckle imaging an...
Bladder dysfunction associated with type 2 diabetes mellitus (T2DM) includes urine storage and voiding disorders. We examined pathological conditions of the bladder wall in a rat T2DM model evaluated effects phosphodiesterase-5 (PDE-5) inhibitor tadalafil.
症例は65歳男性．健診で腫瘍マーカー（CEA，CA19-9）高値を指摘され，前医消化器内科を紹介受診．造影CTで両側腎結石，左尿管結石，前立腺癌疑いを指摘され前医泌尿器科を受診．直腸診正常，PSA1.23ng/mlと正常範囲内であり，前立腺癌疑いは経過観察とされ左尿管結石に対する加療目的に当科紹介．当科でもCEA，CA19-9高値であり，造影MRIでは前立腺右葉に囊胞性病変を認めた．前立腺粘液腺癌や前立腺肉腫を否定できないことから前立腺生検と左尿管結石に対するTULを予定した．術中に前立腺部尿道に腫瘍性病変を認めたことからTULを中止し，診断目的に経尿道的腫瘍切除術，経直腸的前立腺生検を施行した．病理結果はadenocarcinomaであったことから膀胱前立腺尿道全摘術，尿管皮膚瘻造設術，骨盤内リンパ節郭清術を施行した．病理所見や免疫染色所見（PSA陰性，CDX-2陽性，CK20陽性，34β-E12陽性）より前立腺由来のmucin-producing urothelial-type adenocarcinomaと診断した．術後にCEA,...
When pleural empyema is treated with open-window thoracostomy, only 35% of cases are successfully closed, requiring an average 4.5 months treatment until wound closure. Conventional treatments such as daily gauze replacement often result in insufficient re-expansion the collapsed lung, and surgical procedures thoracoplasty, muscle flap transposition, omentoplasty necessary. We report a case acute secondary to coronavirus disease 2019 negative-pressure therapy (NPWT). After month conservative...
<b>Background:</b> Catamenial pneumothorax (CP) is a relatively rare disease, which form of recurring in women reproductive age. The actual cause still unclear. <b>Objectives:</b> To perform histopathologic evaluation the etiology CP. <b>Methods:</b> We retrospectively reviewed intraoperative findings and pathological specimens with who underwent surgery from January 2014 to December 2019. Five patients were suspected CP based on clinical history, computed tomography images showed no bullae....