Maria Bikou

ORCID: 0000-0003-3170-939X
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About
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Research Areas
  • Single-cell and spatial transcriptomics
  • Congenital heart defects research
  • RNA modifications and cancer

New York University
2024

Abstract During development, stem and progenitor cells divide transition through germ layer- lineage-specific multipotent states to generate the diverse cell types that compose an animal. Defined changes in biomolecular composition underlie progressive loss of potency acquisition characteristics. For example, cardiopharyngeal progenitors display multilineage transcriptional priming, whereby both cardiac pharyngeal muscle programs are partially active coexist same cells, while their daughter...

10.1101/2024.07.23.604718 preprint EN cc-by-nd bioRxiv (Cold Spring Harbor Laboratory) 2024-07-23
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