Nicole Kaplan

ORCID: 0000-0003-3308-8726
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About
Contact & Profiles
Research Areas
  • Head and Neck Cancer Studies
  • Cancer-related molecular mechanisms research
  • Cancer Genomics and Diagnostics
  • Cervical Cancer and HPV Research
  • Genomic variations and chromosomal abnormalities
  • RNA modifications and cancer
  • Single-cell and spatial transcriptomics
  • Viral-associated cancers and disorders
  • Congenital heart defects research

New York University
2024

Columbia University
2022

Abstract Purpose: The purpose of this study was to better understand the complex molecular biomarkers and signatures head neck cancer (HNC) among Black patients identify possible changes associated with HNC disparities. Experimental Design: Molecular subtypes genomic in samples from African European ancestry Cancer Genome Atlas, Memorial Sloan Kettering Center, Broad Institute, MD Anderson John Hopkins University were identified. features (genomic, proteomic, transcriptomic) race alterations...

10.1158/1078-0432.ccr-22-2258 article EN Clinical Cancer Research 2022-12-12

Abstract During development, stem and progenitor cells divide transition through germ layer- lineage-specific multipotent states to generate the diverse cell types that compose an animal. Defined changes in biomolecular composition underlie progressive loss of potency acquisition characteristics. For example, cardiopharyngeal progenitors display multilineage transcriptional priming, whereby both cardiac pharyngeal muscle programs are partially active coexist same cells, while their daughter...

10.1101/2024.07.23.604718 preprint EN cc-by-nd bioRxiv (Cold Spring Harbor Laboratory) 2024-07-23

<div>AbstractPurpose:<p>The purpose of this study was to better understand the complex molecular biomarkers and signatures head neck cancer (HNC) among Black patients identify possible changes associated with HNC disparities.</p>Experimental Design:<p>Molecular subtypes genomic in samples from African European ancestry The Cancer Genome Atlas, Memorial Sloan Kettering Center, Broad Institute, MD Anderson John Hopkins University were identified. Molecular features...

10.1158/1078-0432.c.6533159.v1 preprint EN 2023-04-01

<div>AbstractPurpose:<p>The purpose of this study was to better understand the complex molecular biomarkers and signatures head neck cancer (HNC) among Black patients identify possible changes associated with HNC disparities.</p>Experimental Design:<p>Molecular subtypes genomic in samples from African European ancestry The Cancer Genome Atlas, Memorial Sloan Kettering Center, Broad Institute, MD Anderson John Hopkins University were identified. Molecular features...

10.1158/1078-0432.c.6533159 preprint EN 2023-04-01
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