Richard Lobo

ORCID: 0000-0003-3202-1108
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About
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Research Areas
  • Essential Oils and Antimicrobial Activity
  • Phytochemistry and Biological Activities
  • Ethnobotanical and Medicinal Plants Studies
  • Natural Antidiabetic Agents Studies
  • Phytochemicals and Antioxidant Activities
  • Phytochemicals and Medicinal Plants
  • Oral microbiology and periodontitis research
  • Oral Health Pathology and Treatment
  • Sesame and Sesamin Research
  • Drug-Induced Hepatotoxicity and Protection
  • Toxin Mechanisms and Immunotoxins
  • Computational Drug Discovery Methods
  • Natural product bioactivities and synthesis
  • Genomics, phytochemicals, and oxidative stress
  • Phytochemistry and biological activity of medicinal plants
  • Polysaccharides and Plant Cell Walls
  • Plant Parasitism and Resistance
  • Phytochemistry and Bioactive Compounds
  • Probiotics and Fermented Foods
  • Seaweed-derived Bioactive Compounds
  • Flavonoids in Medical Research
  • Microbial Natural Products and Biosynthesis
  • Phytochemical Studies and Bioactivities
  • Phytoestrogen effects and research
  • Curcumin's Biomedical Applications

Manipal Academy of Higher Education
2015-2024

Pharmac
2013-2020

KLE University
2010

Abstract Background The control of biofilm adherence on tooth surface has always been the keystone periodontal therapeutic systems. However, prevalence gingivitis suggest inadequacy self-performed oral hygiene measures and need for adjunctive aid mechanical plaque control. Oral rinses containing chlorhexidine, widely used however, with certain limitations. Herbal products have reflecting its action as alternative complementary remedy. Hence, purpose present study was to evaluate...

10.1186/s12906-019-2745-8 article EN cc-by BMC Complementary and Alternative Medicine 2019-11-21

Macrosolen parasiticus (L.) Danser belonging to Loranthaceaea (mistletoe family) is a parasitic plant that grows on different host plants such as mango, jack fruit, peepal, neem tree, etc., This study was aimed investigate the anti-cancer activity of methanolic and aqueous extract stem M. parasiticus.To in vitro cytotoxic potential extracts from stems against MCF-7 breast cancer cells by brine shrimp lethality (BSL) bioassay, MTT assay sulforhodamine B (SRB) assay.The were tested human cell...

10.4103/0973-1296.157719 article EN Pharmacognosy Magazine 2015-01-01

We have investigated the possible antihyperglycaemic effects of Sphaeranthus indicus extract in rats rendered diabetic by nicotinamide (120 mgkg(-1) i.p.) and streptozotocin (STZ) (60 i.p). Fasting plasma glucose levels, serum insulin lipid profiles, magnesium glycosylated haemoglobin, changes body weight liver glycogen levels were evaluated normal rats. Oral administration S. for 15 days resulted significant decrease blood increases hepatic levels. treated with alcoholic showed improvement...

10.1211/jpp.60.7.0013 article EN Journal of Pharmacy and Pharmacology 2008-06-12

Fungal infections of skin are one the most common in human beings. The areas which likely to get infected include scalp, hands and feet. Dermatophytes, yeasts moulds three major fungi responsible for infections. Earlier oral antifungal agents were used treatment fungal infection finger toe nails. disadvantages toxicity longer period. Now medicated nail lacquers have been developed i.e. onychomycosis, has less shorter

10.4103/0250-474x.49088 article EN Indian Journal of Pharmaceutical Sciences 2008-01-01

Terminalia catappa Linn (T. catappa) belongs to the family Combretaceae, locally known as Bengal Almond. The plant is have many phytochemicals such carbohydrates, phytosterols, tannins, polyphenols, flavonoids, and saponins. It widely used in treatment of various diseases dermatitis, leprosy, scabies internally for colic, headache hepatitis also, possesses anticancer, antioxidant, antidiabetic, hepatoprotective extracts been shown modify reproductive behavior rats. main objective this study...

10.1016/j.sajb.2021.05.010 article EN cc-by South African Journal of Botany 2021-06-05

This study explores Hesperidin (HP) and its bone-protective effect against Osteoporosis (OP), summarizing healing mechanisms supported by in vitro vivo evidence insights into ethnobotanical significance advanced drug delivery systems. To gather information on the antiosteoporotic potential of HP, we thoroughly searched many scientific databases, including Science Direct, Google Scholar, PubMed, Scopus, for articles published between 1990 2025. Data were collected using keywords traditional...

10.22159/ijap.2025v17i3.53661 article EN International Journal of Applied Pharmaceutics 2025-05-07

Inflammation and oxidative stress can contribute to the etiology of metabolic chronic illnesses. The ability prevent induced diseases such as cancer, cardiovascular disease, Alzheimer's others has been subject global research. Drug-induced liver injury (DILI) pathogenesis be either due or inflammatory response elicited by drug, its metabolite, herbal supplements. Our present research uses computational studies identify a molecule with anti-inflammatory properties that operate an NRF2...

10.1080/07391102.2022.2141885 article EN Journal of Biomolecular Structure and Dynamics 2022-11-03

Terminalia tomentosa bark belongs to the family Combretaceae. The plant is astringent and useful in treatment of ulcers, vata, fractures, hemorrhages, bronchitis, diarrhea. Phytochemical investigation T. confirms presence flavonoids, polyphenols, tannins. has not been investigated for its anti-inflammatory antiarthritic activity. present study was undertaken explore possible Anti-inflammatory activity alcoholic aqueous extracts assessed by vivo methods. In potential evaluated Complete...

10.1155/2019/7898914 article EN cc-by Journal of Toxicology 2019-01-17

Hepatocellular carcinoma (HCC), the most common type of liver cancer accounts for more than one million deaths worldwide. Current treatment modality HCC is marginally effective. Plants belonging to Mistletoe family (Loranthaceae) have been used in chemotherapy many years. The present study was aimed at exploring anti-proliferative, pro-oxidant and pro-apoptotic potential stem Elytranthe parasitica (L.) Danser (EP), a parasitic shrub Loranthaceae.Elytranthe Danser, climbing investigated its...

10.1186/s12906-016-1395-3 article EN cc-by BMC Complementary and Alternative Medicine 2016-10-25

Abstract: Antioxidant potential of sesamol has led to being studied extensively in recent decades for its beneficial role vast aliments. There been a renewed interest this compound recently, due activities such as hepatoprotective, neuroprotective, chemopreventive, anti-inflammatory, cardioprotective, skin protective and antiaging properties which were established various preclinical models. Further studies may be required develop underlying mechanisms investigate biological an optimal dose...

10.5530/ijper.53.2s.46 article EN cc-by-nc-nd Indian Journal of Pharmaceutical Education and Research 2019-05-01

In vitro studies were carried out to evaluate the cytotoxic potential of ethanolic and aqueous extracts from stem Dendrophthoe falcata against human breast cancer cells (MCF-7). Screening these was done using brine shrimp lethality bioassay, MTT assay SRB assay. The results showed significant decrease viability in a concentration-dependent manner. extract D. IC50 107 μg mL-1 112 for MCF-7 thus activity. demonstrated higher activity with 90 98 cells, respectively after 48 h exposure. bioassay...

10.3923/ijcr.2011.47.54 article EN International Journal of Cancer Research 2010-12-15

Abstract Drug-induced liver injury can be caused by any drugs, their metabolites, or natural products due to the inefficient functioning of drug-metabolizing enzymes, resulting in reactive oxygen species generation and leading oxidative stress-induced cell death. For protection against stress, our has various defense mechanisms. One mechanisms is NRF2 pathway, when activated, protects stress. Natural antioxidants such as Sesamol have reported pharmacological activity (hepatoprotective &...

10.1007/s11030-023-10686-8 article EN cc-by Molecular Diversity 2023-07-01

Sansevieria roxburghiana Schult. and f. (Asparagaceae) grows in India, Indonesia, Sri Lanka, tropical Africa. Even though the plant has been traditionally used for treatment of many ailments, antioxidant antiproliferative activities S. methanol extract its fractions have not yet explored.Quantitative estimation phenols different assays were performed using standard methods. Anti-proliferative effect evaluated HCT-116, HeLa, MCF-7, HepG2, A-549 cancer cell lines by...

10.4103/pm.pm_497_16 article EN Pharmacognosy Magazine 2017-01-01

Anisochilus carnosus (L.f.) wall (Lamiaceae), an annual herb which grows at high altitude is used extensively in folk medicine for the treatment of ailments such as gastric ulcer and skin diseases. The aim our study was to evaluate anticancer activity different extracts leaves A.carnosus. An attempt also made estimate luteolin content by HPLC (High Performance Liquid Chromatography).In current study, we explored cytotoxic potential petroleum ether, ethanolic aqueous A.carnosus against breast...

10.1186/1472-6882-14-421 article EN cc-by BMC Complementary and Alternative Medicine 2014-10-28
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