A5088787709- Corneal surgery and disorders
- Ophthalmology and Visual Impairment Studies
- Intraocular Surgery and Lenses
- Glaucoma and retinal disorders
- Ocular Surface and Contact Lens
- Corneal Surgery and Treatments
- Ocular and Laser Science Research
- Retinal and Macular Surgery
- Ocular Infections and Treatments
- Obstructive Sleep Apnea Research
- Dermatology and Skin Diseases
- Olfactory and Sensory Function Studies
- Optical Coherence Tomography Applications
- Geophysics and Gravity Measurements
- Veterinary Equine Medical Research
- Urticaria and Related Conditions
- Inertial Sensor and Navigation
- Infrared Thermography in Medicine
- Adaptive optics and wavefront sensing
- Geodetic Measurements and Engineering Structures
- Retinal Diseases and Treatments
- Optical Systems and Laser Technology
- Allergic Rhinitis and Sensitization
- Medical and Biological Sciences
- Healthcare and Venom Research
Pepose Vision Institute
2008-2023
Dow University of Health Sciences
2020
Washington University in St. Louis
2006-2014
First Hospital of Jilin University
2013
Duke Medical Center
2013
Institut de la Vision
2002-2013
Jilin University
2013
University of Portsmouth
2013
The Ohio State University
2005-2009
Bausch & Lomb (France)
2005-2009
To compare intraocular pressure (IOP) and corneal biomechanical metric changes after myopic laser in situ keratomileusis laser-assisted subepithelial keratectomy (LASEK).Private practice, St. Louis, Missouri, USA.The IOP, markers, Ocular Response Analyzer (ORA) waveform parameters were prospectively measured preoperatively 6 months ablation-matched LASIK eyes (mLASIK group) LASEK (mLASEK group). A retrospectively identified cohort of low myopia (lmLASIK fellow unoperated (control) tested at...
To evaluate the efficacy of cryopreserved amniotic membrane (CAM) in reducing signs and symptoms dry eye disease (DED) a large patient population.A retrospective chart review at 10 clinical sites was done patients with refractory DED who received CAM completed least 3 months follow-up. Data collected were demographics; medical history including previous current ocular treatment, diagnosis, presentations, comorbidity, duration frequency treatment CAM; concomitant medications. The primary...
Purpose To identify risk factors for ectasia after laser in situ keratomileusis (LASIK) by comparing the accuracy of Ectasia Risk Score System (ERSS), Screening Corneal Objective (SCORE) Analyzer, and percentage tissue altered (PTA) predicting occurrence ectasia. Setting Multiple centers 8 countries. Design Retrospective case series. Methods Previously unpublished post-LASIK cases were analyzed. Consecutive patients who had LASIK performed at least 5 years previously with no resultant used...
In Brief Purpose: To evaluate the size, shape, and uniformity of videokeratographic functional optical zone (FOZ) after laser in situ keratomileusis (LASIK) 2 cohorts patients with equivalent amounts preoperative myopic or hyperopic astigmatism. Setting: Pepose Vision Institute, St. Louis, Missouri, USA. Methods: Eyes astigmatism (n = 27 each group) that had LASIK Visx Star S3 were retrospectively selected to match for level refractive error. Slit-scanning videokeratography was performed...
To assess the accuracy of Orbscan II slit-scanning videokeratography for intraocular lens (IOL) calculation in eyes with previous photorefractive surgery myopia.Private practice, St. Louis, Missouri, USA.Corneal power (K) was measured by manual keratometry, Placido-based (Atlas), (Orbscan II), and contact overrefraction 21 post-photoablation having cataract surgery. Postoperative data collected after phacoemulsification were used to back-calculate corneal (BCK). The BCK values statistically...
We present a case of dense, visually significant reticular haze that developed approximately 17 months after uneventful laser-assisted subepithelial keratectomy with mitomycin-C (MMC). The patient was successfully treated manual debridement coupled phototherapeutic and intraoperative MMC.
Purpose: To compare various methods of estimating corneal power for intraocular lens (IOL) calculation in patients with irregular astigmatism. Setting: Pepose Vision Institute, St. Louis, Missouri, USA. Methods: Case reports and review the medical literature. Results: Two astigmatism had an IOL exchange after a “surprise” post-cataract-surgery refraction. In first case, patient refraction +5.50 –0.75 × 69 second –7.00 –1.00 180. The central before was assessed using manual keratometry,...
To apply an objective method to topographically determine functional optical zone (TFOZ) dimensions in order compare ablation centration, and refractive outcomes, following myopic laser situ keratomileusis (LASIK) with without automated, infrared (IR) pupil tracking.Thirty-seven eyes that underwent LASIK using the Technolas 217A active IR tracking (IT) were retrospectively compared 37 matched treated manual (MT). Visual acuity, error, corneal topography measured pre- postoperatively....
While sutureless, cryopreserved amniotic membrane (cAM) has been shown to significantly improve signs and symptoms of dry eye disease (DED), no studies have assessed the association cAM treatment duration differential response in clinical outcomes.A multi-center, retrospective study was conducted on patients with moderate-to-severe DED who were treated self-retained (Prokera® Slim) for 2 7 days. The primary outcome measure DEWS severity score at 1 week, month, 3 months. Secondary measures...
PURPOSE: To compare flap parameters produced by the Zyoptix XP and Hansatome microkeratomes (both Bausch & Lomb) to evaluate preoperative variables contributing thickness variation. SETTING: Private practice, St. Louis, Missouri, USA. METHODS: Flap dimensions in 75 eyes that prospectively had laser situ keratomileusis using microkeratome were compared with a historical control sample of treated microkeratome. The 2 groups matched for mean keratometry, central corneal pachymetry, spherical...
Background: This study measured longitudinal changes in dry eye disease (DED) symptoms and signs following lifitegrast therapy assessed their relationship to tear osmolarity test the hypothesis that a decline is reliable leading indicator of subsequent improvement DED after initiating treatment.Methods: phase IV, prospective, single-arm, open-label, 12-week enrolled subjects aged $18 years with dryness score $40 (0-100 VAS) $308 mOsm/L.Subjects were prescribed ophthalmic solution 5%, twice...
We report a case of dense and visually significant corneal haze after laserassisted subepithelial keratectomy (LASEK). Visually LASEK can be successfully treated with manual debridement intraoperative mitomycin-C.
Am J Ophthalmol. 2002;13:6:808-815. Original study reprint requests: Jay S. Pepose, Pepose Vision Institute, 16216 Baxter Road, Suite 205, Chesterfield, MO 63017.