Brady D. Nelson

ORCID: 0000-0003-3214-8977
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About
Contact & Profiles
Research Areas
  • Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Child and Adolescent Psychosocial and Emotional Development
  • Mental Health Research Topics
  • Neural and Behavioral Psychology Studies
  • Stress Responses and Cortisol
  • Functional Brain Connectivity Studies
  • COVID-19 and Mental Health
  • Attention Deficit Hyperactivity Disorder
  • Heart Rate Variability and Autonomic Control
  • Psychosomatic Disorders and Their Treatments
  • Mental Health and Psychiatry
  • Personality Disorders and Psychopathology
  • Resilience and Mental Health
  • Digital Mental Health Interventions
  • Eating Disorders and Behaviors
  • Neuroendocrine regulation and behavior
  • Behavioral Health and Interventions
  • Suicide and Self-Harm Studies
  • Obsessive-Compulsive Spectrum Disorders
  • Autism Spectrum Disorder Research
  • Neuroscience and Music Perception
  • Mental Health Treatment and Access
  • Psychology of Moral and Emotional Judgment
  • Schizophrenia research and treatment
  • Maternal Mental Health During Pregnancy and Postpartum

Stony Brook University
2016-2025

State University of New York
2024

Amen Clinics
2021

University of Illinois Chicago
2009-2016

AARP
2016

University of Illinois Urbana-Champaign
2014

Uniformed Services University of the Health Sciences
2013

Abstract Background The coronavirus [coronavirus disease 2019 (COVID-19)] pandemic has introduced extraordinary life changes and stress, particularly in adolescents young adults. Initial reports suggest that depression anxiety are elevated during COVID-19, but no prior study explored at the within -person level. current symptoms from before to soon after it first peaked Spring 2020 a sample of adults ( N = 451) living Long Island, New York, an early epicenter COVID-19 U.S. Methods Depression...

10.1017/s0033291720005358 article EN cc-by Psychological Medicine 2021-01-13

A blunted neural response to rewards has recently emerged as a potential mechanistic biomarker of adolescent depression. The reward positivity, an event-related elicited by feedback indicating monetary gain relative loss, been associated with risk for authors examined whether the positivity prospectively predicted development depression 18 months later in large community sample girls.The included 444 girls 13.5-15.5 years old no lifetime history depressive disorder, along biological parent...

10.1176/appi.ajp.2016.15121524 article EN American Journal of Psychiatry 2016-07-01

The Hierarchical Taxonomy of Psychopathology (HiTOP) is a quantitative nosological system that addresses shortcomings traditional mental disorder diagnoses, including arbitrary boundaries between psychopathology and normality, frequent co‐occurrence, substantial heterogeneity within disorders, diagnostic unreliability over time across clinicians. This paper reviews evidence on the validity utility internalizing somatoform spectra HiTOP, which together provide support for an emotional...

10.1002/wps.20943 article EN World Psychiatry 2022-01-11

Heightened sensitivity to threat and reduced reward are potential mechanisms of dysfunction in anxiety depressive disorders, respectively.However, few studies have simultaneously examined whether these unique or common disorders.In this study, predictable unpredictable (measured by startle response during anticipation) frontal electroencephalographic [EEG] asymmetry were assessed 4 groups (N = 191): those with (1) panic disorder (PD) without a lifetime history depression, (2) major...

10.1037/a0030747 article EN Journal of Abnormal Psychology 2012-11-13

Cognitive vulnerabilities, such as a negative self-referential processing bias, have been theorized to play causal role in the development of depression. Indeed, depression is associated with endorsement and recall more fewer positive emotional words (i.e., biases) encoding task (SRET). In addition, currently depressed adults adolescents, compared healthy controls, show an enhanced late potential (LPP), event-related (ERP) component that reflects sustained attentional engagement, during...

10.1037/abn0000173 article EN other-oa Journal of Abnormal Psychology 2016-05-13

An increased neural response to making mistakes has emerged as a potential biomarker of anxiety across development. The error-related negativity (ERN) is an event-related elicited when people make on simple laboratory-based reaction time tasks that been associated with risk for anxiety. This study examined whether the ERN prospectively predicted first onset generalized disorder (GAD) over 1.5 years in adolescent girls.The sample included 457 girls between ages 13.5 and 15.5 years, no history...

10.1111/jcpp.12922 article EN Journal of Child Psychology and Psychiatry 2018-04-17

Abstract The startle reflex is a robust measure of defense system activation. Startle probes also elicit ERP P300 and N100 responses that capture attentional engagement. probe‐elicited have been primarily examined during affective picture viewing paradigms, no study has these measures in the context threat anticipation task or relation to predictability. In present study, 131 participants completed (N), predictable (P), unpredictable (U) threat‐of‐shock task, eye blink reflex, P300, probe...

10.1111/psyp.12418 article EN Psychophysiology 2015-02-22

A heightened sensitivity to unpredictable aversiveness is a key component of several anxiety disorders. Neuroimaging studies have shown that the anterior region insula cortex (AIC) plays central role in anticipation aversiveness. The present study extended these findings by examining AIC temporal unpredictability (i.e. not knowing when stimulus will occur), particularly critical aspect as it increases contextual and vigilance, given danger could happen ‘at any time’. Nineteen healthy...

10.1097/wnr.0000000000000144 article EN Neuroreport 2014-03-10

Neuroticism and extraversion are multifaceted affective-laden personality traits that have been associated with major depressive disorder (MDD). Research theory argued extraversion, particularly its facet positive emotionality, is specific to MDD, while neuroticism common across internalizing disorders. Converging evidence has suggested MDD reduced engagement emotional stimuli, but it remains unclear whether either neuroticism, or both modulate reactivity cues. The late potential (LPP) an...

10.1111/psyp.12436 article EN Psychophysiology 2015-04-05

Blunted reward processing both characterizes major depressive disorder and predicts increases in symptoms. However, little is known about the interaction between blunted other risk factors relation to Stressful life events sleep problems are prominent that contribute etiopathogenesis of depression have been linked dysfunction; these may interact with dysfunction predict increased In a large sample 8- 14-year-old adolescent girls, current study examined how processing, stressful events, at...

10.1080/15374416.2019.1630834 article EN Journal of Clinical Child & Adolescent Psychology 2019-07-22

10.1016/j.ijpsycho.2020.05.001 article EN International Journal of Psychophysiology 2020-05-14

Abstract An aberrant neural response to rewards has been linked both depression and social anxiety. Most studies have focused on the monetary rewards, few tested different modalities of reward (e.g. social) that are more salient particular forms psychopathology. In addition, most contain critical confounds, including contrasting positive negative feedback failing disentangle being correct from obtaining feedback. present study, 204 participants underwent electroencephalography during tasks...

10.1093/scan/nsab055 article EN cc-by-nc Social Cognitive and Affective Neuroscience 2021-05-04

Objective The COVID-19 pandemic has worsened college students' mental health while simultaneously creating new barriers to traditional in-person care. Teletherapy and online self-guided supports are two potential avenues for addressing unmet needs when face-to-face services less accessible, but little is known about factors that shape interest in these supports. Participants: 1,224 U.S. undergraduate students (mean age = 20.7; 73% female; 40% White) participated. Methods: Students completed...

10.1080/07448481.2022.2062245 article EN Journal of American College Health 2022-04-15

Deficits in cognitive and reward-related functions, measured via reductions the P300 reward positivity (RewP) event-related potential (ERP) components, are commonly observed adults suffering with depression. Considering higher risk for depression emerges among females adolescence, examination of neurological underpinnings during this critical developmental period can help further elucidate our overall understanding etiology depressive disorders. Therefore, present study sought to first...

10.1111/psyp.70009 article EN Psychophysiology 2025-02-01

Two emotional/motivational constructs that have been posited to underlie anxiety and depressive disorders are heightened sensitivity threat reduced reward, respectively. It is unclear, though, whether these only epiphenomena or also connote risk for (and relatedly, they separate disorders). Using family history of psychopathology as an indicator risk, the present study examined biomarkers (startle potentiation) reward (frontal EEG asymmetry) were associated with similar different familial...

10.1037/a0033982 article EN Journal of Abnormal Psychology 2013-08-01

Unpredictability increases amygdala activity and vigilance toward threat. The error-related negativity (ERN) is an electrophysiological response to errors posited reflect sensitivity potential present study examined whether the ERN was modulated by predictable or unpredictable task-irrelevant auditory stimuli. Twenty-three participants completed a speeded task designed elicit ERN, were simultaneously exposed tone sequences. Participants retrospectively rated their anxiety sequences indicated...

10.1037/emo0000020 article EN Emotion 2014-08-24

Affective science research on reward processing has primarily focused monetary rewards. There been a growing interest in evaluating the neural basis of social decision-making and processing. The present study employed within-subject design compared positivity (RewP), an event-related potential component that is following favorable feedback absent or reduced unfavorable feedback, during tasks. Specifically, 114 participants (75 females) completed task novel were matched trial structure,...

10.1093/scan/nsy006 article EN cc-by-nc-nd Social Cognitive and Affective Neuroscience 2018-01-22
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