A5075712280- Synthesis and Properties of Aromatic Compounds
- Supramolecular Self-Assembly in Materials
- Polydiacetylene-based materials and applications
- Photochromic and Fluorescence Chemistry
- Liquid Crystal Research Advancements
- Luminescence and Fluorescent Materials
- Molecular spectroscopy and chirality
- Photoreceptor and optogenetics research
- Analytical Chemistry and Chromatography
- Immune Cell Function and Interaction
- Surface Chemistry and Catalysis
- Axial and Atropisomeric Chirality Synthesis
- Tactile and Sensory Interactions
- Supramolecular Chemistry and Complexes
- T-cell and B-cell Immunology
- EEG and Brain-Computer Interfaces
- Robot Manipulation and Learning
- Immune Response and Inflammation
- Soft Robotics and Applications
- Muscle activation and electromyography studies
- Carbohydrate Chemistry and Synthesis
- Neuroscience and Neuropharmacology Research
- Advanced Computational Techniques and Applications
- Advanced Polymer Synthesis and Characterization
- Gut microbiota and health
Imperial College London
2023-2025
Life Science Institute
2024-2025
Kanazawa University
2024-2025
Soochow University
2018-2024
Shanghai Ocean University
2024
Soochow University
2024
Anhui University of Finance and Economics
2024
Jiangxi Agricultural University
2024
Bohai University
2024
Jiangxi Maternal and Child Health Hospital
2023
PD-1, a receptor expressed by T cells, B and monocytes, is potent regulator of immune responses promising therapeutic target. The structure interactions human PD-1 are, however, incompletely characterized. We present the solution nuclear magnetic resonance (NMR)-based extracellular region detailed analyses its with ligands, PD-L1 PD-L2. has typical immunoglobulin superfamily topology but differs at edge GFCC' sheet, which flexible completely lacks C" strand. Changes in backbone NMR signals...
Immune responses to persistent viral infections and cancer often fail because of intense regulation antigen-specific T cells—a process referred as immune exhaustion. The mechanisms that underlie the induction exhaustion are not completely understood. To gain novel insights into this process, we simultaneously examined dynamics virus-specific CD8+ CD4+ cells in living spleen by two-photon microscopy (TPM) during establishment an acute or infection. We demonstrate persistence maps anatomically...
Abstract Inspired by the mystery of natural homochirality, design and construction artificial chiral systems with special functions including mechanics, chiroptical devices, separation have aroused great interest scientists. Due to its diverse conformations components, polymers become an excellent candidate construct aggregates, which provides opportunity fabricate advanced materials. Herein, in this review, we summarized not only different strategies for regulation supramolecular chirality...
Circularly polarized luminescence (CPL) plays a pivotal role in cutting-edge display and information technologies. Currently achieving precise color control dynamic signal regulation CPL still remains challenging due to the elusory relationship between fluorescence chirality. Inspired by natural mechanisms governing formation chiral interaction, we proposed an addition-subtraction principle theory address this issue. Three fluorene-based polymers synthesized Suzuki polycondensation with...
Hierarchical supramolecular chiral liquid-crystalline (LC) polymer assemblies are challenging to construct in situ a controlled manner. Now, polymerization-induced self-assembly (PICSA) is reported. azobenzene-containing block copolymer (Azo-BCP) were constructed with π-π stacking interactions occurring the layered structure of Azo smectic phases. The evolution chirality from terminal alkyl chain mesogen building blocks and further induction LC BCP during PICSA achieved. Morphologies such as...
Abstract Supramolecular chirality and its complete self‐recovery ability are highly mystical in nature biological systems, which remains a major challenge today. Herein, we demonstrate that partially cross‐linked azobenzene (Azo) units can be employed as the potential chiral trigger to fully heal destroyed helical superstructure achiral nematic polymer system. Combining self‐assembly of Azo terminal hydroxyl groups side chains allows vapor‐induced phase covalent fixation via acetal reaction....
While controlling the chirality and modulating helicity is a challenging task, it attracts great research interest for gaining better understanding of origin in nature. Herein, structurally similar azobenzene (Azo) vinyl monomers were designed which alkyl chains comprised chiral stereocenter with different achiral tail lengths. Combining synchronous polymerization, supramolecular stacking self-assembly, multiple chiroptical inversion Azo-polymer assemblies can be modulated by length DP Azo...
Controlling the secondary phase in chiral liquid-crystalline (LC) polymers is of great importance since it transfers and amplifies molecular information to macroscopic properties. However, superstructures LC are determined exclusively by inherent configuration parent source. Here, we report switchable supramolecular chirality heteronuclear structures untraditional command between common "sergeant" units various achiral "soldier" units. Different induction pathways sergeants soldiers were...
Abstract Chirality is a fundamental property in nature, which essential for the existence and survival of living organisms. Smart responsive chiroptical materials have garnered increasing attention due to their unique structural characteristics potential applications. Among these, azobenzene (Azo), as typical photoresponsive chromophore, plays crucial role constructing controlling chiral structures. The cis ‐ trans isomerization, liquid crystallinity, other physicochemical properties allow...
Abstract This paper presents a comprehensive multi-modal dataset capturing concurrent haptic, audio, and visual signals recorded from ten participants as they interacted with different textured surfaces using their bare fingers. The includes stereoscopic images of the textures, fingertip position, speed, applied load, emitted sound, friction-induced vibrations, providing an unprecedented insight into complex dynamics underlying human tactile perception. Our approach utilizes finger (while...
Unraveling the chirality transfer mechanism is key to governing chiral expression and structure–property relationships further constructing new functional devices. Herein, we have systematically investigated assembly, transfer, modulation of block copolymers (BCPs) at molecular, supramolecular, liquid-crystalline (LC) phase, macroscopic morphological levels. It revealed that strength LC ordering Azo mesogens, solvophobic length core-forming blocks, coupling effects between polymer side...
Precise control over the chirality and morphologies of polymer assemblies, a remaining challenge for both chemists materials scientists, is receiving ever-increasing attention in recent years. Herein, we report subtle manipulation achiral spacers from chiral stereocenter to azobenzene (Azo) unit, which chiroptical consistency or inversion self-assemblies could be successfully controlled present "two-fold" odd-even effect. Furthermore, morphological transitions 0D spherical micelles, 1D...
The synthesis of chiral substances, especially polymers is currently one the hottest issues in field materials and chemistry due to their unique structural characteristics potential applications. However, acquisition by chemical or asymmetric catalysis may often involve expensive reagents tedious routes. types substances nature are undoubtedly limited. Except for design compounds, utilizing external stimulus factors induce chirality achiral a promising approach. Inspired nature, researchers...
Soluble dietary fiber (SDF) benefits human health, and different extraction methods might modify the structure functions of SDFs. Radish is rich in fiber. To assess impact various techniques on properties radish SDF, SDFs were obtained from white pomace using alkaline, ultrasonic-assisted, fermentation-assisted methods. Analysis was conducted structure, physicochemical characteristics, thermal properties, functional attributes The study revealed that can monosaccharides composition...
A chiral liquid crystalline elastomer (CLCE) actuator is demonstrated. The solution-cast polydomain film of CLCE can twist upon order-disorder phase transition without any preset alignment mesogens. handedness twisting specific to the molecular chirality dopant in structure, while degree twisting, terms helical pitch and diameter, sensitive aspect ratio thickness strip as well content. This phenomenon appears stem from local forces deformations randomly oriented domains, which cannot cancel...
The evolution of hierarchical chirality at macromolecular and supramolecular levels in biological systems is ubiquitous; however, achieving precise control over transitions between them polymer still challenging. Here, we reported multiple chiroptical inversion phenomena side-chain azobenzene (Azo) polymers, PAzo-l/d-m (m = 3, 6, 7, 8, 9, 10, where m the total number atoms from chiral stereocenter to Azo unit), with different distances unit. In case an unexpected...
In nature, the communication of primary amino acids in polypeptides influences molecular-level packing, supramolecular chirality, and resulting protein structures. chiral side-chain liquid crystalline polymers (SCLCPs), however, hierarchical between mesogens is still determined by parent source due to intermolecular interactions. Herein, we present a novel strategy enable tunable chiral-to-chiral azobenzene (Azo) SCLCPs, which chiroptical properties are not dominated configurational point...
Macroscopic regulation of chiral supramolecular nanostructures in liquid-crystalline block copolymers is great significance photonics and nanotechnology. Although fabricating helical phase structures via doping microphase separation has been widely reported, the memory self-recovery capacity asymmetric are major challenge still deeply rely on presence additives. Herein, we demonstrate first controllable an achiral amphiphilic copolymer consisting poly(ethylene oxide) azobenzene (Azo) groups....
Abstract New insights are raised to interpret pathway complexity in the supramolecular assembly of chiral triarylamine tris‐amide (TATA) monomer. In cosolvent systems, monomer undergoes entirely different processes depending on chemical feature two solvents. Specifically, 1,2‐dichloroethane (DCE) and methylcyclohexane (MCH) trigger cooperative growth monomers with M helical arrangement, hierarchical thin nanobelts further formed. But DCE hexane (HE) combination, a occurs where go through...