A5037959136- Phytochemical compounds biological activities
- Biosensors and Analytical Detection
- Amino Acid Enzymes and Metabolism
- Gold and Silver Nanoparticles Synthesis and Applications
- Fungal Biology and Applications
- Polyamine Metabolism and Applications
- Pharmacological Effects of Natural Compounds
- Flavonoids in Medical Research
- Biological Activity of Diterpenoids and Biflavonoids
- Medicinal Plants and Bioactive Compounds
- Neonatal Respiratory Health Research
- Infant Nutrition and Health
- Electronic Health Records Systems
- Cell death mechanisms and regulation
- Survey Methodology and Nonresponse
- Bladder and Urothelial Cancer Treatments
- Mitochondrial Function and Pathology
- Anesthesia and Sedative Agents
- T-cell and Retrovirus Studies
- Natural product bioactivities and synthesis
- NF-κB Signaling Pathways
- Rheumatoid Arthritis Research and Therapies
- Patient Safety and Medication Errors
- Marine Sponges and Natural Products
- Optical Coatings and Gratings
National Pingtung University
2010-2025
Chung Shan Medical University
2005-2009
National Taiwan University
2002-2007
Chung Shan Medical University Hospital
2005
National Tsing Hua University
1996
Cancer diagnostics often faces challenges, such as invasiveness, high costs, and limited sensitivity for early detection, emphasizing the need improved approaches. We present a surface-enhanced Raman scattering (SERS)-based platform leveraging inverted pyramid SU-8 nanostructured substrates fabricated via nanoimprint lithography. These substrates, characterized by sharp apices edges, are further functionalized with (3-aminopropyl)triethoxysilane (APTES), enabling uniform self-assembly of...
The effects of the flavonoids from Scutellaria baicalensis Georgi (baicalein, baicalin and wogonin) in cultured human hepatoma cells (Hep G2, Hep 3B SK-Hep1) were compared by MTT assay flow cytometry. All three dose-dependently decreased cell viabilities accompanying collapse mitochondrial membrane potential depletion glutathione content. However, influence baicalein, or wogonin on cycle progression was different. resulted prominent increase G2/M population G2 cells, whereas an accumulation...
Calvatia lilacina (CL), Pleurotus ostreatus (PO) and Volvariella volvacea (VV) are widely distributed worldwide commonly eaten as mushrooms. In this study, cell viabilities were evaluated for a human colorectal adenocarcinoma line (SW480 cells) monocytic leukemia (THP-1 cells). Apoptotic mechanisms induced by the protein extracts of PO VV SW480 cells. The THP-1 cells decreased in concentration-dependent manner after 24 h treatment with CL, or VV. Apoptosis analysis revealed that percentage...
Bladder cancer is one of the most common malignancies in urinary system. Cystoscopy traditional standard diagnostic method for bladder with subsequent biopsy or surgery. However, this uncomfortable patients because it requires anesthesia and possibly causes infections. Because high recurrence rate cancer, a rapid, low-cost, high-sensitivity, noninvasive sensing needed. This study employed gold nanomushroom (AuNM) chips biomarker detection, combining benefits sandwich immunoassay localized...
Technological advances and critical needs have led to medication administration devices tools designed prevent reduce errors. They include smart carts, robots dispensers for professionals naive users. This paper describes architectures interfaces of these devices. It also discusses support environment that is needed increase their effectiveness missing standards will enable integration into process tool chain.
The paper presents a simple, fast, and cost-effective method for creating metal/SU-8 nanocomposites by applying metal precursor drop onto the surface or nanostructure of SU-8 exposing it to UV light. No pre-mixing with polymer pre-synthesis nanoparticles is required. A TEM analysis was conducted confirm composition depth distribution silver nanoparticles, which penetrate film uniformly form Ag/SU-8 nanocomposites. antibacterial properties were evaluated. Moreover, composite top layer gold...
Chemical examination of Sinularia querciformis afforded one new cembranoid, querciformolide F (1), along with four known cembranoids, sinulariolone (2), granosolide A (3), (4), and sinulariolide (5). The structures these compounds were determined by extensive spectroscopic (IR, ESIMS, 1 H NMR, 13 C NMR) analysis comparison those previously reported in the literature. Compounds 2 to 4 found exhibit significant anti-inflammatory activity lipopolysaccharide (LPS)-induced RAW264.7 mouse...
Background: Propofol, thiopental, citosol, and midazolam are widely used as sedatives for the critically ill in intensive care unit. These patients usually suffer from cellular injuries caused by oxidative stress free radicals, predominantly due to lack of a sufficient defense system against these species. Therefore, antioxidant activities sedative drugs may be clinically important. We attempt evaluate reactive oxygen species scavenging relevant intravenous sedatives. Methods: By using...