A5102924902- Machine Learning in Bioinformatics
- Antibiotic Resistance in Bacteria
- Bioinformatics and Genomic Networks
- Forecasting Techniques and Applications
- Genomics and Phylogenetic Studies
- Antibiotic Use and Resistance
- Data Mining and Machine Learning Applications
- Pneumonia and Respiratory Infections
- Biochemical and Structural Characterization
- Bacterial Infections and Vaccines
- Microbial infections and disease research
- Protein Structure and Dynamics
- Probabilistic and Robust Engineering Design
- Pneumocystis jirovecii pneumonia detection and treatment
- vaccines and immunoinformatics approaches
- Enterobacteriaceae and Cronobacter Research
- Bacteriophages and microbial interactions
- Statistical Distribution Estimation and Applications
- Healthcare Quality and Satisfaction
- Reliability and Maintenance Optimization
- Rabies epidemiology and control
- Enzyme Production and Characterization
- Food Safety and Hygiene
- Insurance and Financial Risk Management
- Stock Market Forecasting Methods
University of Indonesia
2015-2024
Rumah Sakit Umum Pusat Nasional Dr. Cipto Mangunkusumo
2013-2024
Osaka University
2024
Oxford University Clinical Research Unit Indonesia
2018
Eijkman Institute for Molecular Biology
2018
University of Oxford
2018
Padjadjaran University
2018
Fluconazole is the standard treatment for oropharyngeal candidiasis, which third most common opportunistic infection in human immunodeficiency virus (HIV)/AIDS patients Indonesia. Overuse of this drug could lead to emergence resistance. The objective study was analyse role ERG11, CDR1, CDR2 and MDR1 gene overexpression mutations ERG11 as a genetic mechanism fluconazole resistance Candida albicans isolated from HIV Overexpression analysed by real-time reverse transcription PCR, while mutation...
Little detailed knowledge is available regarding the etiology and outcome of CNS infection, particularly in HIV-infected individuals, low-resource settings.From January 2015 to April 2016, we prospectively included all adults with suspected infection a referral hospital Jakarta, Indonesia. Systematic screening HIV testing, CSF examination, neuroimaging.A total 274 patients (median age 26 years) presented after median 14 days headache (77%), fever (78%), seizures (27%), or loss consciousness...
Objective: The objectives of this study were to determine the minimum inhibitory concentration (MIC) Salam bark extract against Staphylococcusaureus, formulate and evaluate hand sanitizer gels containing extract, effectiveness bacteria on thepalms hands.Methods: gel base was optimized by preparing three formulations carbomer triethanolamine at ratios 0.25%:0.5%, 0.5%:1%,and 0.5%:2%. best formulation mixed with extract. physical stability 4.04% (formulation 1) 7.77%(formulation 2) measured...
A recent modeling study estimated that there could be as many 20,000 human melioidosis cases per year in Indonesia, with around 10,000 potential deaths annually. Nonetheless, the true burden of Indonesia is still unknown. The Melioidosis Network was formed during first workshop 2017. Here, we reviewed 101 (99 and two animal cases) previously reported described an additional 45 cases. All 146 culture-confirmed were found Sumatra (
Weibull distribution is the most popular in wind speed energy literature. However, real life, data may not always modelled by distribution. An alternative modeling inverse Inverse modifications from with transformation variables. Marshall and Olkin (1997) introduced an interesting method of adding a parameter to well established so we extend Invers Marshall-Olkin (IWMO). The probability density function (pdf), cumulative (cdf), hazard rate, survival function, moment quantiles IWMO are...
Markov Clustering is a grouping of graph algorithms based on stochastic flow simulation. This method consists three main steps such as expansion, inflation, and prune. MCL has the limitation finding effective parameter for inflation factor since it specified by user. In this research, we use Cuckoo Search Optimization Algorithm to find automatically from data PPI HIV applying in clustering interaction proteins presented form network where protein vertices edges. The result shows that optimal...
If information about the mortality rate for some future periods can be obtained in present time then financial planning and policy to taken are expected better directed. The model used calculate this paper is Lee-Carter model. There three parameters of model, that ax, bx kt. Parameter ax will estimate using average log while kt Singular Value Decomposition (SVD) method. Then rates forecast with use ARIMA (Auto Regressive Integrated Moving Average) Meanwhile, whole process study implemented...
Abstract Analysing the relationship between number of crime cases and affecting factors became an interesting research topic over last ten years. The total in Indonesia did not show a consistent decrease. In order to upgrade people safeness quality, government need know influence committing acts. Rather than using classical regression analysis, geographically weighted (GWR) was preferable since it gave better representative model by effectively resolve spatial non-stationary problem which is...
As a well-known clustering algorithm, Markov Clustering (MCL) has been used in many areas due to its simplicity and the ability detect cluster of different sizes shapes for example bioinformatics. MCL shows good performance as fast scalable unsupervised algorithm graphs. However, limitation is that results are mostly dependent on inflation parameter whose value user specified. In this paper, we develop new method named PIO-MCL detected protein-protein interaction network by using...
Penilitian ini bertujuan untuk mengetahui prevalensi MRSA penghasil Panton-Valentine leukocidin (PVL) dan pola kepekaannya. Sampel penelitian adalah isolat dari 315 pasien Rumah Sakit Umum Pusat Nasional Cipto Mangunkusumo (RSUPNCM) selama tahun 2011 2014, dengan melakukan identifikasi, uji kepekaan molekuler terhadap tersebut. Penelitian menunjukkan sebanyak 59% koloni yang ditemukan masih sensitif antibiotik golongan selain β-laktam, sehingga dapat diduga sebagai community-associated...
In any sport competition, there is a strong interest in knowing which team shall be the champion at end of championship and one sports football. Football match predictions are great to fans press. last few years, it has been focus several studies. this paper, researchers propose Poisson regression model predict final result football matches. The predicted average goals scored by each assuming that number followed univariate distribution. was formulated from four covariates: goal match,...
Dengue virus consists of 10 different constituent proteins and are classified into 4 major serotypes (DEN 1 - DEN 4). This study was designed to perform clustering against 30 protein sequences dengue taken from Virus Pathogen Database Analysis Resource (VIPR) using Regularized Markov Clustering (R-MCL) algorithm then we analyze the result. By Python program 3.4, R-MCL produces 8 clusters with more than one centroid in several clusters. The number shows density level interaction. Protein...
Proteins are bio-macromolecules that have an important role in living organisms. This type of protein consists a series combinations 20 amino acids. In organisms, Protein-Protein Interactions (PPIs) most biological processes so by detecting interactions will be able to understand molecular mechanisms systems. By using the calculation process and applying machine learning method, it more efficient than experimental method takes long time expensive cost. The novelty this paper we use Support...
Human Immunodeficiency Virus is a type of intracellular obligate retrovirus that attacks the human body's immune system. This virus by doing interaction between and proteins. research uses data amino acids sequence from protein feature will be modified using Global Encoding as extraction method then combined with Rotation Forest in predicting HIV The first group 20 types into 6 classes get 10 combinations each containing three different classes. Based on these combinations, transformed...
Protein plays a vital role in the structure and function of all living cell viruses. The protein will interact with each other molecules which regulate metabolism, cellular process system organism, so that protein-protein interactions networks have considerable size. To learn network interaction is required clustering algorithm. One most commonly used algorithms Markov algorithm (MCL). But results depend on its inflate parameters inputted by user. In this study, we combined Fruit Fly...
BACKGROUND: Antibiotic resistance has become a worldwide problem. Among Asia countries, Indonesia high prevalence of multi-drug resistant organisms mainly due to Gram-negative bacilli Enterobacteriaceae. This study aimed find out whether gene family AmpC and AmpC/ESBL-producing Enterobacteriaceae were present in the Intensive Care Unit (ICU) Cipto Mangunkusumo Hospital, Jakarta, Indonesia.METHODS: Specimens obtained from several body sites adult patients with infection hospitalised ICU...
BACKGROUND: Community-acquired pneumonia (CAP) is the most common infectious with serious rate of morbidity and mortality. Recent conventional method only described 30-50% CAP etiology. Sputum specimen quality assessment important to obtain an accessible CAP-causing pathogens identification.METHODS: This was a prospective descriptive study involving 100 specimens from CAP-diagnosed subjects in Budhi Asih Regional General Hospital inpatien tcare. We assessed three gram-staining criteria for...
Physical tests are an important part of forming high-achieving athletes and the main element in a coach's training program. This study aims to: (1) Produce physical fitness test based on Vald Performance with Nordbord tool for football school at Askot PSSI West Jakarta; (2) Determine feasibility response to use by athletes; (3) Analyze results athletes' abilities using test. uses qualitative method descriptive analysis. The development process involves validation experts field sports...
Pneumococcal pneumonia is a significant cause of illness and death globally, particularly among young children the elderly. The cpsB gene involved in biosynthesis capsule polysaccharide, polymorphisms are basis for sequetyping, molecular biology-based approach to serotyping. In this study, we attempted sequetyping pneumococci directly from clinical sputum specimens collected adult patients diagnosed with community-acquired (CAP). We performed conventional PCR gene, followed by TA cloning...
Abstract Tuberculosis is a disease that can affect socio-economic development. Based on data from the World Health Organization, there were 810,918 tuberculosis cases in Indonesia, which noted as third-highest number of Asia 2016. Prevention and control are considerable importance, especially insurance field, to cover cost treatment, so an accurate model morbidity needed. The method used forecasting rate Autoregressive Integrated Moving Average (ARIMA) method. ARIMA time series widely...