A5077920461- Renal cell carcinoma treatment
- Renal and related cancers
- Bladder and Urothelial Cancer Treatments
- Testicular diseases and treatments
- Acute Ischemic Stroke Management
- Prostate Cancer Diagnosis and Treatment
- Pediatric Urology and Nephrology Studies
- Diabetic Foot Ulcer Assessment and Management
- Renal and Vascular Pathologies
- Urological Disorders and Treatments
- Global Cancer Incidence and Screening
- Genital Health and Disease
- MRI in cancer diagnosis
- Primary Care and Health Outcomes
- Urinary and Genital Oncology Studies
- Pressure Ulcer Prevention and Management
- Pharmaceutical Practices and Patient Outcomes
- Pelvic floor disorders treatments
- Sarcoma Diagnosis and Treatment
- Urologic and reproductive health conditions
- Nursing Roles and Practices
- Wound Healing and Treatments
- Colorectal and Anal Carcinomas
- Neurosurgical Procedures and Complications
- Intracerebral and Subarachnoid Hemorrhage Research
The University of Texas MD Anderson Cancer Center
2019-2025
University of Oklahoma Health Sciences Center
2022-2024
Fox Chase Cancer Center
2018-2023
Philadelphia University
2015-2019
Heidenhain (Germany)
2019
Temple University Hospital
2018
Temple University Health System
2017-2018
Astley Ainslie Hospital
2015
The University of Texas at San Antonio
2012
University of Sheffield
1999-2010
Background The management of metastatic renal cell carcinoma (mRCC) has evolved rapidly, and results from the Cancer du Rein Metastatique Nephrectomie et Antiangiogéniques (CARMENA) trial bring into question utility cytoreductive nephrectomy (CN). objective this study was to examine overall survival (OS) identify risk factors associated with patients less likely benefit CN in targeted therapy era. Methods Patients mRCC undergoing 2005 2017 were identified. Kaplan‐Meier methods Cox...
<b>Aim:</b> To explore the factor structure, reliability, and potential usefulness of a patient safety climate questionnaire in UK health care. <b>Setting:</b> Four acute hospital trusts nine primary care England. <b>Methods:</b> The used was 27 item Teamwork Safety Climate Survey. Thirty three healthcare staff commented on wording relevance. then sent to 3650 within 13 NHS trusts, seeking achieve at least 600 responses as basis for analysis. 1307 questionnaires were returned (36% response)....
570 Background: The use of ctDNA-based molecular residual disease detection represents a promising prognostic biomarker in multiple solid tumors, yet limited data exist RCC. This study aims to prospectively assess the utility longitudinal ctDNA monitoring localized and metastatic Methods: We conducted retrospective analysis on testing single academic center for patients with RCC from 2022 - 2024. used clinically validated, personalized, tumor-informed, PCR-NGS assay (Signatera, Natera, Inc.)...
Objectives To develop a clinically applicable predictive model to quantitate the risk of estimated glomerular filtration rate (eGFR) decline ≤45 mL/min/1.73 m 2 after radical nephrectomy (RN) better inform decisions between RN and partial (PN). Patients Methods Our prospectively maintained kidney cancer registry was reviewed for patients with preoperative eGFR >60 who underwent localized renal mass. New baseline function indexed. We used multivariable logistic regression nomogram...
We evaluated oncologic risks in a large cohort of patients with radiographic cystic renal masses who underwent active surveillance or intervention.A single-institutional database 4,340 kidney lesions managed either intervention between 2000-2020 was queried for radiographically masses. Association tumor characteristics and high-grade pathology evaluated.We identified 387 confirmed 367 patients. Of these, 247 were resected (n=240) ablated (n=7; n=247, 203 immediate vs 44 delayed...
Methamphetamine use may be associated with increased risk of stroke in young adults. We describe two cases carotid artery dissection and ispilateral middle cerebral (MCA) following methamphetamine use. ### Patient 1. A 36-year-old right-handed woman had sudden onset speech difficulty right-sided weakness while eating lunch. She presented to the emergency department within 30 minutes. Her medical history was significant for migraine oral contraceptive use. smoking some left neck pain over...
Pharmacist prescribing is a relatively new initiative in the extension of responsibilities to non-medical healthcare professionals. supplementary was introduced 2003 and allowed accordance with clinical management plan agreed medical practitioner patient improve access medicines better utilize skills The objective this research examine volume, cost trends pharmacist community primary care using Prescription Analysis Cost (PACT) data suggest possible reasons for trends.Using PACT at national,...
To develop a model for using routine data monitoring in the evaluation of clinical guideline usage primary healthcare settings.A framework was developed following number semistructured interviews with potential users. These informed postal survey among random sample professionals. Then to test out framework, further interview study used explore practical issues relating use. Case studies were then undertaken investigate use evidence-based review criteria and patient-centred outcome measures...
<h3>Objectives</h3> To determine which of the two methods case note review provide most useful and reliable information for reviewing quality care. <h3>Design</h3> Retrospective, multiple reviews 692 notes were undertaken using both holistic (implicit) criterion-based (explicit) methods. Quality measures evidence-based criteria a care rating scale. <h3>Setting</h3> Nine randomly selected acute hospitals in England. <h3>Participants</h3> Sixteen doctors, 11 specialist nurses three clinically...
Abstract Objective To define the value of a digital rectal exam (DRE) in prostate‐magnetic resonance imaging (MRI) era. Prostate MRI is increasingly used men with elevated prostate‐specific antigen (PSA) prior to biopsy. Methods A retrospective study was performed PSA undergoing followed by fusion systematic biopsy and PSA/active surveillance negative Baseline clinicopathologic characteristics DRE findings were collected. We examined performance positive on sensitivity specificity diagnosing...
Background Postchemotherapy retroperitoneal lymphadenectomy (PC‐RPLND) is an essential, yet potentially morbid, therapy for the management of patients with advanced germ cell tumors. In current study, authors sought to define complication profile PC‐RPLND using validated grading systems intraoperative adverse events (iAEs) and early postoperative complications. Methods Between 2000 2018, all who underwent were analyzed iAEs complications Kaafarani Clavien‐Dindo classifications, respectively....
Aims and Method A pre-/post-intervention audit of 163 case notes was conducted to assess the efficacy printing information about identification treatment Wernicke–Korsakoff syndrome on hospital alcohol detoxification sheet. Results Parenteral thiamine indicated in 42 patients; 26 had symptoms suggestive Wernicke's encephalopathy 16 were at risk. The intervention increased chance appropriate parenteral by an odds ratio 5.9 (95% CI 1.3–27.8). Admission a specialist unit 7.0 1.52–32.25). mean...
Background: Radical cystectomy is associated with perioperative complication rates exceeding 50% in some series. Readmission are increasingly used as a surgical quality metric. White blood cell count crude surrogate for physiologic processes which may reflect postoperative complications leading to readmission. Objective: We assessed the association between final white at discharge and risk of readmission following radical cystectomy. Methods: Records on 477 patients undergoing from 2006-2013...
Penile cancer, most commonly squamous cell carcinoma (SCC), is rare in the United States and Europe but has an aggressive natural history. Due to disease rarity, randomized clinical trials demonstrating efficacious multimodal therapies for advanced are lacking. Multi-agent cisplatin-based neoadjuvant chemotherapy (NAC) utilizing “TIP” regimen (paclitaxel, ifosfamide, cisplatin) demonstrated good response rates TxN2-3 disease.1 Clinical responders NAC who undergo consolidative surgery show...