Jian Zhao

ORCID: 0009-0007-6536-2028
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About
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Research Areas
  • Lung Cancer Treatments and Mutations
  • Cancer, Lipids, and Metabolism
  • Cancer Diagnosis and Treatment
  • Machine Learning in Bioinformatics
  • Inflammatory Biomarkers in Disease Prognosis
  • Kruppel-like factors research
  • Muscle Physiology and Disorders
  • Molecular Biology Techniques and Applications
  • Medical Imaging and Pathology Studies
  • Radiopharmaceutical Chemistry and Applications
  • Multiple and Secondary Primary Cancers
  • Mesenchymal stem cell research
  • Prostate Cancer Diagnosis and Treatment
  • Extracellular vesicles in disease
  • Immune cells in cancer
  • Global Cancer Incidence and Screening
  • Radiomics and Machine Learning in Medical Imaging
  • Pancreatic and Hepatic Oncology Research
  • Toxin Mechanisms and Immunotoxins
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Bone Metabolism and Diseases
  • Esophageal Cancer Research and Treatment
  • Myeloproliferative Neoplasms: Diagnosis and Treatment
  • Protease and Inhibitor Mechanisms
  • PARP inhibition in cancer therapy

Jiangnan University
2025

University of Oklahoma Health Sciences Center
2024

Taian City Central Hospital
2023

Qingdao University
2023

Viva Biotech (China)
2023

Shandong University
2020

Guangdong Pharmaceutical University
2012

Guangzhou Medical University Cancer Hospital
2011

Guangzhou Medical University
2011

Quzhou City People's Hospital
2009

Microvesicles (MVs) are membrane vesicles secreted by cells and present in the saliva of healthy individuals. It has various functions been reported to be a biomarker for malignant tumors. The changes levels MVs associated with disease(s) is unclear. This study aimed determine proportion salivary apoptotic their association oral ulcer(s) patients non-healing cancer. Saliva (5 mL) was collected from cancer (at time collection, participant have an cavity lesion; n = 73) volunteers (n 62). A...

10.1038/s41598-025-93075-5 article EN cc-by-nc-nd Scientific Reports 2025-03-18

Poly ADP ribose polymerase (PARP) inhibitors are mainly used in treating BRCA-mutant cancers, and their application novel therapies to expand benefit is of interest personalized medicine.A recent report showed that pharmacological targeting PARP increases the sensitivity cancer cells EGFR inhibition, but therapeutic value this combination has not been fully determined.We propose a strategy combining with bispecific antibodies target both Notch signalling, highlighting difficulties posed by...

10.7150/thno.82144 article EN cc-by Theranostics 2023-01-01

Stable regulation of protein fate is a prerequisite for successful bone tissue repair. As ubiquitin-specific protease (USP), USP26 can stabilize the β-catenin to promote osteogenic activity mesenchymal cells (BMSCs) and significantly increased regeneration in defects aged mice. However, direct transfection Usp26 vivo inefficient. Therefore, improving efficient expression target key promoting Herein, 3D printing combined with microfluidic technology applied construct functional microunit...

10.1002/smtd.202301375 article EN Small Methods 2023-12-24

To analyze the association between platelet count of peripheral blood and clincopathologic parameters esophageal carcinoma.Platelets were measured in 415 cases carcinoma 325 healthy subjects as control. The correlation counts clinicopathological features cancer was analyzed.Platelet patients with carcinomas (286+/-88)x10(9)/L significantly higher than that control [(204+/-114)x10(9)/L, P<0.05 ]. Increased (>300 x 10(9)/L) associated tumor infiltration lymph node metastasis (P<0.05).Platelet...

10.3785/j.issn.1008-9292.2009.02.009 article EN PubMed 2009-03-01

Objective To investigate the perioperative weight loss and its influencing factors in patients with colorectal cancer, to provide evidence for development management of nutritional support strategies. Methods Ninety-one cancer were enrolled divided into observation group (n=61) degree less than 5% preoperative control (n=30) more weight. Change body composition compared between two groups by single factor multivariate analysis. Results Ninety-one had average 2.0 kg. Of changes...

10.3760/cma.j.issn.1674-635x.2019.05.006 article EN Zhonghua linchuang yingyang zazhi 2019-10-30

Abstract BackgroundWith the popularization of high-resolution computed tomography (HRCT), detection rate synchronous multiple primary lung cancer (SMPLC) is increasing. We retrospectively analyzed surgical results SMPLC patients in our hospital to determine best treatment, prognosis and survival analysis.MethodsA total 78 met diagnostic criteria underwent complete resection lymph node dissection or sampling without any preoperative induction therapy Department Thoracic Surgery, Qilu...

10.21203/rs.3.rs-135673/v1 preprint EN cc-by Research Square (Research Square) 2020-12-29
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