A5089003870- Periodontal Regeneration and Treatments
- Mesenchymal stem cell research
- Cancer-related molecular mechanisms research
- Bone Tissue Engineering Materials
- Oral and Maxillofacial Pathology
- Dental Implant Techniques and Outcomes
- Bone Tumor Diagnosis and Treatments
- Oral and gingival health research
- Cancer, Hypoxia, and Metabolism
- Oral Health Pathology and Treatment
- Extracellular vesicles in disease
Shanghai East Hospital
2018-2025
The aim of the present study was to evaluate clinical efficacy platelet-rich fibrin (PRF) in preserving alveolar ridge following human tooth extraction. A total 28 patients were divided into two groups: experimental and control groups (n=14 each). Following extraction, group implanted with PRF membrane, whereas not. gingival healing effect assessed at 7 days, 1 3 months later. Cone-beam computed tomography performed immediately changes height, width, bone mineral density compared between...
Abstract Background Long non-coding RNAs (lncRNAs) have been widely known to an appreciable effect in physiology and pathology. In tooth regeneration, periodontal ligament stem cells (PDLSCs) are regarded as a key effector, whereas, how lncRNA acts the osteogenic differentiation of PDLSCs not completely understood. This study aims find out relationship between DANCR proliferation PDLSCs. Methods Microarray was used observe different expression lncRNAs differentiated undifferentiated And then...
Microvesicles (MVs) are membrane vesicles secreted by cells and present in the saliva of healthy individuals. It has various functions been reported to be a biomarker for malignant tumors. The changes levels MVs associated with disease(s) is unclear. This study aimed determine proportion salivary apoptotic their association oral ulcer(s) patients non-healing cancer. Saliva (5 mL) was collected from cancer (at time collection, participant have an cavity lesion; n = 73) volunteers (n 62). A...
Hypoxia-inducible factor (HIF)-1α protein, which is upregulated by hypoxia, serves an important role in angiogenesis during osteogenesis. The aim of the present study was to investigate effect HIF-1α on alveolar ridge preservation a dog tooth extraction model. Six beagle dogs were used study. second and fourth premolar teeth lower jaws both sides extracted. Two unilateral sockets randomly selected filled with Bio-Oss + HIF-1α. contralateral remained unfilled served as negative control....
Abstract Backgrounds: Long non-coding RNAs (lncRNAs) have been widely known to an appreciable effect in physiology and pathology. In tooth regeneration, periodontal ligament stem cells (PDLSCs) are regarded as a key effector, whereas, how lncRNA acts the osteogenic differentiation of PDLSCs haven’t completely understood. This study aims find out relationship between DANCR proliferation PDLSCs. Results: Compared with undifferentiated PDLSCs, alizarin red staining level was higher...
Abstract Backgrounds: Long non-coding RNAs (lncRNAs) have been widely known to an appreciable effect in physiology and pathology. In tooth regeneration, periodontal ligament stem cells (PDLSCs) are regarded as a key effector, whereas, how lncRNA acts the osteogenic differentiation of PDLSCs not completely understood. This study aims find out relationship between DANCR proliferation PDLSCs. Method: Microarray was used observe different expression lncRNAs differentiated undifferentiated And...